Results 61 to 70 of about 13,827 (215)

PTX Instructs the Development of Lung-Resident Memory T Cells in Bordetella pertussis Infected Mice

Toxins, 2021
Whooping cough is a severe, highly contagious disease of the human respiratory tract, caused by Bordetellapertussis. The pathogenicity requires several virulence factors, including pertussis toxin (PTX), a key component of current available vaccines ...
Julie Tomas, Yoon Koo, Dimitri Popoff, Vilma Arce-Gorvel, Sean Hanniffy, Jean-Pierre Gorvel, Cyrille Mionnet   +6 more
doaj   +1 more source

Detection of small RNAs in Bordetella pertussis and identification of a novel repeated genetic element [PDF]

, 2011
Background Small bacterial RNAs (sRNAs) have been shown to participate in the regulation of gene expression and have been identified in numerous prokaryotic species. Some of them are involved in the regulation of virulence in pathogenic bacteria. So far,
David Hot, Stéphanie Slupek, Bérénice Wulbrecht, Anthony D'Hondt, Christine Hubans, Rudy Antoine, Camille Locht, Yves Lemoine   +7 more
core   +1 more source

Differential Regulation of Bvg-Activated Virulence Factors Plays a Role in Bordetella pertussis Pathogenicity [PDF]

Infection and Immunity, 2001
ABSTRACT Bordetella pertussis , the causative agent of whooping cough, regulates expression of many virulence factors via a two-component signal transduction system encoded by the bvgAS regulatory locus.
S M, Kinnear, R R, Marques, N H, Carbonetti   +2 more
openaire   +2 more sources

Clinical and computed tomography findings of fatal poxviral vasculitis in a domestic shorthair cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract This report describes the clinical presentation, haematological abnormalities and imaging findings of systemic poxvirus infection in a cat that resulted in widespread severe dermal oedema and systemic inflammatory response syndrome. The cat lacked cutaneous lesions before the onset of dermal oedema, but developed crusting skin lesions and a ...
Mica Taylor, Harriet R. Hall, Hannah Wong, Lorraine Peschard, Emanuele Ricci, Katie E. McCallum   +5 more
wiley   +1 more source

Genome dynamics of Bartonella grahamii in micro-populations of woodland rodents [PDF]

, 2010
Background Rodents represent a high-risk reservoir for the emergence of new human pathogens. The recent completion of the 2.3 Mb genome of Bartonella grahamii, one of the most prevalent blood-borne bacteria in wild rodents, revealed a higher abundance of
Eva C Berglund, Christian Ehrenborg, Olga Vinnere Pettersson, Fredrik Granberg, Kristina Näslund, Martin Holmberg, Siv GE Andersson   +6 more
core   +2 more sources

Orthoquinone, Cyclic, and Acyclic α‐Diketone Natural Products: From Food Applications to Pharmacotherapy

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain, Daijie Wang, Satyajit D. Sarker, Lutfun Nahar, Nilufar Z. Mamadalieva, Jianbo Xiao   +5 more
wiley   +1 more source

The diverse landscape of AB5-type toxins

Engineering Microbiology, 2023
AB5-type toxins are a group of secreted protein toxins that are central virulence factors for bacterial pathogens such as Shigella dysenteriae, Vibrio cholerae, Bordetella pertussis, and certain lineages of pathogenic Escherichia coli and Salmonella ...
Paris I. Brown, Adaobi Ojiakor, Antonio J. Chemello, Casey C. Fowler   +3 more
doaj   +1 more source

Polymorphism inBordetella pertussisPertactin and Pertussis Toxin Virulence Factors in the United States, 1935–1999 [PDF]

The Journal of Infectious Diseases, 2000
To elucidate the potential role of the etiologic agent in recent increases of pertussis incidence in the United States, we studied the polymorphism in pertactin and pertussis toxin, which are Bordetella pertussis proteins important for pathogenesis and immunity. We sequenced regions of their genes (prn and ptx) in 152 B. pertussis strains isolated from
Cassiday, P, Sanden, G, Heuvelman, Krivm, Mooi, Frivm, Bisgard, KM, Popovic, T   +5 more
openaire   +4 more sources

The contribution of BvgR, RisA, and RisS to global gene regulation, intracellular cyclic-di-GMP levels, motility, and biofilm formation in Bordetella bronchiseptica

Frontiers in Microbiology
Bordetella bronchiseptica is a highly contagious respiratory bacterial veterinary pathogen. In this study the contribution of the transcriptional regulators BvgR, RisA, RisS, and the phosphorylation of RisA to global gene regulation, intracellular cyclic-
Tracy L. Nicholson, Ursula Waack, Ursula Waack, Damarius S. Fleming, Qing Chen, Laura C. Miller, Tod J. Merkel, Scott Stibitz   +7 more
doaj   +1 more source

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń, Julia Karbowska, Wiktoria Pietrowicz, Robert Stasiuk, Łukasz Drewniak   +4 more
wiley   +1 more source