Results 61 to 70 of about 7,870 (170)

The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System. [PDF]

open access: yesPLoS ONE, 2015
Bordetella bronchiseptica is genetically related to B. pertussis and B. parapertussis, which cause respiratory tract infections in humans. These pathogens possess a large number of virulence factors, including the type III secretion system (T3SS), which ...
Akio Abe   +4 more
doaj   +1 more source

Perspectives on Pertussis Prevention

open access: yes
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Variation in the Bordetella pertussis Virulence Factors Pertussis Toxin and Pertactin in Vaccine Strains and Clinical Isolates in Finland [PDF]

open access: yesInfection and Immunity, 1999
ABSTRACT There is evidence that pertussis is reemerging in vaccinated populations. We have proposed, and provided evidence for, one explanation for this phenomenon in The Netherlands: antigenic divergence between vaccine strains and circulating strains.
Mooi, FR   +3 more
openaire   +4 more sources

New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

open access: yesVaccines, 2015
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez   +4 more
doaj   +1 more source

Chronic Productive Cough in an Immunosuppressed Patient due to Biologics: A Rare Case of Bordetella bronchiseptica Pulmonary Infection

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
This case illustrates features of ground glass changes on radiology in a patient who was immunosuppressed with biologics. Microbiology confirmed infection with Bordetella bronchiseptica, highlighting the importance of looking for atypical infections in patients receiving biologics and the importance of pet ownership history.
Debashree Banerjee   +5 more
wiley   +1 more source

The Role of Virulence Proteins in Protection Conferred by Bordetella pertussis Outer Membrane Vesicle Vaccines

open access: yesVaccines, 2020
The limited protective immunity induced by acellular pertussis vaccines demands development of novel vaccines that induce broader and longer-lived immunity.
René H. M. Raeven   +11 more
doaj   +1 more source

Metagenomic and Phenotypic Insights Into Biofilm‐Forming Pathogens in Patients With Nosocomial Sepsis

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Biofilm‐related infections significantly contribute to bacterial diseases, with estimates suggesting that at least 80% of such infections are associated with biofilms. These infections often involve opportunistic pathogens, which not only influence the type of infection but also impact the microenvironment by interacting with other polymicrobial ...
Haleema Sadia   +3 more
wiley   +1 more source

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis.

open access: yesProceedings of the National Academy of Sciences, 1990
Regulation of the genes coding for virulence factors in Bordetella pertussis is controlled by the bvg locus, which encodes one putative sensory protein (BvgS) and one positive regulator of transcription (BvgA). We have studied the transcription of the bvg locus and found that this is controlled by a 350-base-pair DNA fragment, which contains five ...
Scarlato V.   +3 more
openaire   +4 more sources

Effect of mutations causing overexpression of RNA polymerase alpha subunit on regulation of virulence factors in Bordetella pertussis [PDF]

open access: yesJournal of Bacteriology, 1994
In Bordetella pertussis, expression of virulence factors is controlled by the Bvg proteins, which comprise a sensor-regulator two-component signal transduction system. Previously, we described a mutant strain of B. pertussis that had reduced transcription of pertussis toxin and adenylate cyclase toxin genes, while other virulence factors were ...
N H, Carbonetti   +5 more
openaire   +2 more sources

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

open access: yesCase Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa   +7 more
wiley   +1 more source

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