Results 81 to 90 of about 13,827 (215)

The Role of Virulence Proteins in Protection Conferred by Bordetella pertussis Outer Membrane Vesicle Vaccines

Vaccines, 2020
The limited protective immunity induced by acellular pertussis vaccines demands development of novel vaccines that induce broader and longer-lived immunity.
René H. M. Raeven, Naomi van Vlies, Merijn L. M. Salverda, Larissa van der Maas, Joost P. Uittenbogaard, Tim H. E. Bindels, Jolanda Rigters, Lisa M. Verhagen, Sabine Kruijer, Elly van Riet, Bernard Metz, Arno A. J. van der Ark   +11 more
doaj   +1 more source

Genome characterization and population genetic structure of the zoonotic pathogen, streptococcus canis [PDF]

, 2012
Background - Streptococcus canis is an important opportunistic pathogen of dogs and cats that can also infect a wide range of additional mammals including cows where it can cause mastitis. It is also an emerging human pathogen.
Lang, P., Lefébure, T., Moroni, P., Pavinski Bitar, P.D., Richards, V.P., Stanhope, M.J., Tikofsky, L., Werner, B., Zadoks, R.N.   +8 more
core   +5 more sources

Effect of mutations causing overexpression of RNA polymerase alpha subunit on regulation of virulence factors in Bordetella pertussis [PDF]

Journal of Bacteriology, 1994
In Bordetella pertussis, expression of virulence factors is controlled by the Bvg proteins, which comprise a sensor-regulator two-component signal transduction system. Previously, we described a mutant strain of B. pertussis that had reduced transcription of pertussis toxin and adenylate cyclase toxin genes, while other virulence factors were ...
N H, Carbonetti, T M, Fuchs, A A, Patamawenu, T J, Irish, H, Deppisch, R, Gross   +5 more
openaire   +2 more sources

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa, Aryan Shiari, Marina Antic, Buddhi P. Hatharaliyadda, Juan Vera Gomez, David Ladin, Igor Dumic, Tun-Chieh Chen   +7 more
wiley   +1 more source

Allelic variations between vaccine strains and circulating strains in pxtP of Bordetella pertussis in Iran

Vaccine Research, 2015
Introduction: Despite high level of vaccination against pertussis‚ whooping cough has re-emerged as a health threat, especially in infants. This could be related to expansion of Bordetella pertussis with novel alleles for virulence factors including the ...
F Sadeghpour Heravi, VS Nikbin, F Shahcheraghi   +2 more
doaj  

Genetic relatedness and antimicrobial susceptibility of porcine respiratory tract pathogens Streptococcus suis, Bordetella bronchiseptica and Pasteurella multocida [PDF]

, 2019
Streptococcus suis is a Gram-positive bacterium and a commensal colonizing the porcine respiratory tract. However, some serotypes have a higher virulence and can cause pneumonia, meningitis, septicaemia, arthritis, endocarditis, polyserositis or abortion
Niemann, Lisa
core   +1 more source

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis.

Proceedings of the National Academy of Sciences, 1990
Regulation of the genes coding for virulence factors in Bordetella pertussis is controlled by the bvg locus, which encodes one putative sensory protein (BvgS) and one positive regulator of transcription (BvgA). We have studied the transcription of the bvg locus and found that this is controlled by a 350-base-pair DNA fragment, which contains five ...
Scarlato V., Prugnola A., Arico B., Rappuoli R.   +3 more
openaire   +4 more sources

Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species [PDF]

BMC Genomics, 2016
The genus Bordetella consists of nine species that include important respiratory pathogens such as the 'classical' species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and less extensively studied species. Here we analyze sequence diversity and gene content of 128 genome sequences from all nine species with focus ...
Linz, Bodo, Ivanov, Yury V., Preston, Andrew, Brinkac, Lauren, Parkhill, Julian, Kim, Maria, Harris, Simon R., Goodfield, Laura L., Fry, Norman K., Gorringe, Andrew R., Nicholson, Tracy L., Register, Karen B., Losada, Liliana, Harvill, Eric T.   +13 more
openaire   +3 more sources

A Deep Metagenomic Snapshot as a Proof‐of‐Concept for Resource Generation: Simultaneous Assembly of Host, Food, and Microbiome Genomes From Stingless Bee Larval Food

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study serves as a proof‐of‐concept, demonstrating that deep shotgun sequencing of a single complex sample—stingless bee larval food—can simultaneously generate multiple genomic resources. From this dataset, we assembled three genomes (a near‐complete bacterium, a draft host mitochondrion, and a fragmented plant chloroplast) with varying ...
Carlos Ueira‐Vieira, Ana Carolina Costa Santos, Thayane Nogueira Araújo, Solange Cristina Augusto, Natanael Borges de Avila, Ana Maria Bonetti, Anderson Rodrigues dos Santos   +6 more
wiley   +1 more source

Phylogeny, Synteny, and Distribution of Type III Secretion Systems in Burkholderia cenocepacia: A Closer Look Into Host Span

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
T3SS is a dedicated machinery that mediates interactions between bacteria and eukaryotic cells, providing a functional interface in pathogenic or symbiotic associations. Phylogenetic analyses and T3SS‐gene synteny revealed nine gene clusters, with no needle protein gene (sctF). However, an orphan CDS encoding a putative SctF was found.
Gabrielle Tomé Cordeiro, Hadassa Loth de Oliveira, Danielly C. O. Mariano, Yasmin Salazar Torres, Graciela Maria Dias, Bianca C. Neves   +5 more
wiley   +1 more source