Results 91 to 100 of about 8,047 (199)

Production and secretion of virulence factors in Bordetella pertussis

open access: yes, 2015
Bordetella pertussis is a strictly human pathogen and causative agent of infectious respiratory disease called whooping cough. In order to establish successful infection and colonization of the host, B.
Držmíšek, Jakub
core   +1 more source

Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion

open access: yesToxins, 2014
The past decade has seen a fundamental reappraisal of the protein structure-to-function paradigm because it became evident that a significant fraction of polypeptides are lacking ordered structures under physiological conditions.
Ana-Cristina Sotomayor-Pérez   +2 more
doaj   +1 more source

Bordetella Type III Secretion Injectosome and Effector Proteins

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Pertussis, also known as whooping cough, is a resurging acute respiratory disease of humans primarily caused by the Gram-negative coccobacilli Bordetella pertussis, and less commonly by the human-adapted lineage of B. parapertussisHU.
Jana Kamanova
doaj   +1 more source

Evolution of Physiology and Virulence in Bordetella

open access: yes
Pertussis (whooping cough) is an acute, re-emerging disease and global health threat. Bordetella pertussis, the causative agent, survives only in the human respiratory tract and briefly during transmission between hosts. B.
Wolber, Alexa Rae
core   +1 more source

Differential response of the bvg virulence regulon of Bordetella pertussis to MgSO4 modulation

open access: yes, 1991
Magnesium sulfate is known to repress the expression of the virulence factors of Bordetella pertussis that are coordinately regulated by the bvg locus.
Rappuoli R., Scarlato V.
core   +1 more source

Genome implosion elicits host-confinement in Alcaligenaceae: evidence from the comparative genomics of Tetrathiobacter kashmirensis, a pathogen in the making.

open access: yesPLoS ONE, 2013
This study elucidates the genomic basis of the evolution of pathogens alongside free-living organisms within the family Alcaligenaceae of Betaproteobacteria. Towards that end, the complete genome sequence of the sulfur-chemolithoautotroph Tetrathiobacter
Wriddhiman Ghosh   +10 more
doaj   +1 more source

TRANSCRIPTIONAL REGULATION AND PROTECTIVE EFFICACY OF BORDETELLA COLONIZATION FACTOR A (BcfA) IN BORDETELLA INFECTIONS

open access: yes, 2009
To successfully colonize their mammalian hosts many bacteria produce multiple virulence factors that play essential roles in disease processes and pathogenesis.
Sukumar, Neelima
core  

Strukturní hmotnostní spektrometrie faktorů virulence rodu Bordetella [PDF]

open access: yes, 2020
The Bordetellae are aerobic Gram-negative coccobacilli colonizing the upper respiratory tract of mammals and thereby causing diseases with similar symptoms but different host specificity.
Jurnečka, David
core  

The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis

open access: yesmBio
Bordetella pertussis is the causative agent of whooping cough in humans, a disease that has recently experienced a resurgence. In contrast, Bordetella bronchiseptica infects the respiratory tract of various mammalian species, causing a range of symptoms ...
Martin Zmuda   +9 more
doaj   +1 more source

Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

open access: yesToxins, 2017
Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease.
Helena Ostolaza   +4 more
doaj   +1 more source

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