Results 91 to 100 of about 13,827 (215)

The BvgAS Regulon of Bordetella pertussis

mBio, 2017
Nearly all virulence factors in Bordetella pertussis are activated by a master two-component system, BvgAS, composed of the sensor kinase BvgS and the response regulator BvgA.
Kyung Moon, Richard P. Bonocora, David D. Kim, Qing Chen, Joseph T. Wade, Scott Stibitz, Deborah M. Hinton   +6 more
doaj   +1 more source

Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]

, 2014
Bis-(3 ',5 ') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence.
A Teplyakov, C Momany, C Saveanu, CD Boyd, CR Guzzo, D-G Ha, David Mackey, Delphine L. Caly, F Tao, GG Anderson, H Mulcahy, H Slater, H Sondermann, IS Pultz, J Duevel, J Mansfield, J Nesper, J. Maxwell Dow, Joseph Ward, K-H Chin, KB Twomey, Melanie Febrer, MY Galperin, R Hengge, Robert P. Ryan, RP Ryan, RP Ryan, RP Ryan, RP Ryan, RP Ryan, RP Ryan, S Moreau-Marquis, S-Q An, S-Q An, S-Q An, Sarah L. Murdoch, SE Maddocks, Shi-qi An, T Lundback, T Schirmer, U Romling, X Qiao, X-H Lu, Y Fouhy, Y McCarthy, Y McCarthy, Yvonne McCarthy   +46 more
core   +5 more sources

The importance of Bordetella pertussis strains which do not produce virulence factors in the epidemiology of pertussis

Postępy Higieny i Medycyny Doświadczalnej, 2017
Bordetella pertussis strains, which have lost the ability to produce antigens, such as pertactin - Prn, pertussis toxin - Ptx, filamentous haemagglutinin - FHA, fimbriae type 2 and 3 - Fim 2 and 3, tracheal colonization factor - TcfA, have recently been isolated in countries with a high vaccination coverage.
Maciej, Polak, Anna, Lutyńska
openaire   +2 more sources

Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert, Klaudia Naegele, Marvin Weiss, Roland Bingisser, Christian H. Nickel, Jakob Meyer, Martin Siegemund, Stefano Bassetti, Sarah Dräger, Christoph T. Berger, Fabian Franzek, Ulrich Heininger, Julia Bielicki, Hans H. Hirsch, Peter M. Keller, Maja Weisser, Nina Khanna, Sarah Tschudin‐Sutter, Karoline Leuzinger   +18 more
wiley   +1 more source

Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]

, 1991
Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred, Timmis, Kenneth N., Walker, Mark J., Wehland, Jurgen   +3 more
core  

Virulence factors of Bordetella bronchiseptica associated with the production of infectious atrophic rhinitis and pneumonia in experimentally infected neonatal swine [PDF]

Infection and Immunity, 1987
Four strains of Bordetella bronchiseptica (CSU-P-1, 64-C-0406, 1120-A-83-013, and B205BT) with defined virulence for neonatal swine were examined, and an attempt was made to correlate the presence of certain in vitro phenotypic characteristics with the ability of a particular B.
R M, Roop, H P, Veit, R J, Sinsky, S P, Veit, E L, Hewlett, E T, Kornegay   +5 more
openaire   +2 more sources

Significance of Bordetella bronchiseptica in Respiratory Tract Infections of Canines

International Journal of Bio-Resource and Stress Management
Bordetella bronchiseptica is one of the major pathogens affecting canine respiratory tract. The agent is transmitted through aerosol mode, contact with contaminated faces or urine as well as through infected fomites. The agent affects all age groups and
Kh. Thanila Rose, J. B. Rajesh, S. C. Marwein, P. Kar, S. K. Behera, G. E. Chethan, H. Bayan, J. M. Rao, K. Sarma, H. Prasad   +9 more
doaj   +1 more source

Targeting virulence not viability in the search for future antibacterials [PDF]

, 2014
New antibacterials need new approaches to overcome the problem of rapid antibiotic resistance. Here we review the development of potential new antibacterial drugs that do not kill bacteria or inhibit their growth, but combat disease instead by targeting ...
Aberg, Arnon, Babcock, Bader, Bardwell, Bardwell, Bebbington, Bouckaert, Busch, Cegelski, Cegelski, Chan, Chatterjee, Chorell, Dailey, Duncan, Enquist, Escaich, Felise, Fruh, Garcia-Contreras, Ha, Hentzer, Heras, Hirakawa, Hu, Hu, Hung, Inaba, Infectious Disease Society of America, Ireland, Jacob-Dubuisson, Jang, Jubb, Keller, LaSarre, Lazar, Maeda, Maresso, Miki, Miller, Mitchell, Miyairi, Mohamed, Morkunas, Ochsner, Peek, Piatek, Pinkner, Qin, Rasko, Rasmussen, Riddle, Romero, Russell, Sarkar-Tyson, Schmitt, Sheoran, Sintim, Slepenkin, Stenson, Stevens, Subramanian, Suree, Suree, Tay, Tinsley, Tomb, Totsika, Totsika, Touaibia, Ur-Rehman, Vitale, Watarai, Wolf, Zhang, Zhu, Zucca   +77 more
core   +1 more source

Soil Properties Induced Changes in the Microbial Communities Associated With Potato Tubers Grown in Different Lowland Fields of Northern Thailand

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
Microbial communities on potato tubers in northern Thailand were studied with 16S and ITS amplicon sequencing. It was found that soil pH and organic matter are key drivers of bacterial and fungal composition, affecting the balance between pathogens and beneficial microbes.
Pipat Macharoen, Wuttichai Mhuantong, Thippawan Wannawong, Wiphawee Leesutthiphonchai, Onuma Piasai, Somboon Tanasupawat, Nakarin Suwannarach, Nattakorn Kuncharoen   +7 more
wiley   +1 more source

Practical Application of Disease Risk Assessment in Native Species Reintroductions: A Case Study of a European Wildcat (Felis silvestris) Population Reinforcement in the Cairngorms National Park

Mammal Review, Volume 55, Issue 4, October 2025.
Disease risk assessment was conducted for the Saving Wildcats reintroduction project of captive‐bred European Wildcats (Felis silvestris) to the Cairngorms National Park. Hazards were identified, and appropriate pre‐and post‐release mitigation strategies were identified and implemented, illustrating the direct conservation application and significance ...
Alice Bacon, Beatriz S. G. Alves, Simon Girling, Adam Naylor   +3 more
wiley   +1 more source