Results 71 to 80 of about 8,047 (199)

Variation in the Bordetella pertussis Virulence Factors Pertussis Toxin and Pertactin in Vaccine Strains and Clinical Isolates in Finland [PDF]

Infection and Immunity, 1999
ABSTRACT There is evidence that pertussis is reemerging in vaccinated populations. We have proposed, and provided evidence for, one explanation for this phenomenon in The Netherlands: antigenic divergence between vaccine strains and circulating strains.
Mooi, FR, He, Q, van Oirschot, H, Mertsola, J   +3 more
openaire   +4 more sources

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa, Aryan Shiari, Marina Antic, Buddhi P. Hatharaliyadda, Juan Vera Gomez, David Ladin, Igor Dumic, Tun-Chieh Chen   +7 more
wiley   +1 more source

Allelic variations between vaccine strains and circulating strains in pxtP of Bordetella pertussis in Iran

Vaccine Research, 2015
Introduction: Despite high level of vaccination against pertussis‚ whooping cough has re-emerged as a health threat, especially in infants. This could be related to expansion of Bordetella pertussis with novel alleles for virulence factors including the ...
F Sadeghpour Heravi, VS Nikbin, F Shahcheraghi   +2 more
doaj  

New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

Vaccines, 2015
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez, Nicolas Hegerle, Francesco Strati, Elisabeth Njamkepo, Nicole Guiso   +4 more
doaj   +1 more source

The Role of Virulence Proteins in Protection Conferred by Bordetella pertussis Outer Membrane Vesicle Vaccines

Vaccines, 2020
The limited protective immunity induced by acellular pertussis vaccines demands development of novel vaccines that induce broader and longer-lived immunity.
René H. M. Raeven, Naomi van Vlies, Merijn L. M. Salverda, Larissa van der Maas, Joost P. Uittenbogaard, Tim H. E. Bindels, Jolanda Rigters, Lisa M. Verhagen, Sabine Kruijer, Elly van Riet, Bernard Metz, Arno A. J. van der Ark   +11 more
doaj   +1 more source

Effect of mutations causing overexpression of RNA polymerase alpha subunit on regulation of virulence factors in Bordetella pertussis [PDF]

Journal of Bacteriology, 1994
In Bordetella pertussis, expression of virulence factors is controlled by the Bvg proteins, which comprise a sensor-regulator two-component signal transduction system. Previously, we described a mutant strain of B. pertussis that had reduced transcription of pertussis toxin and adenylate cyclase toxin genes, while other virulence factors were ...
N H, Carbonetti, T M, Fuchs, A A, Patamawenu, T J, Irish, H, Deppisch, R, Gross   +5 more
openaire   +2 more sources

Isolation and Characterization of a Highly Virulent Getah Virus Causing Acute Lethal Infection in Neonatal Piglets

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Getah virus (GETV) is a mosquito‐borne alphavirus with an expanding host range and an increasing impact on swine production, particularly in neonatal piglets. In this study, a severe disease outbreak characterized by acute diarrhea and high mortality occurred among suckling piglets on a commercial pig farm in central China.
Zhengxin Yang, Weidong Yan, Xuefei Wang, Mengjia Zhang, Zongyang Peng, Mengdi Zhang, Ahmed H. Ghonaim, Xuexiang Yu, Thi Trang Vy, Xugang Ku, Mingguang Zhou, Gaoyuan Xu, Anan Jongkaewwattana, Qigai He, Wentao Li, Shao-Lun Zhai   +15 more
wiley   +1 more source

Epidemiology, Phylogenetic Divergence, and Differential Pathogenicity of Feline Respiratory Mycoplasma in China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Mycoplasma felis (M. felis) is a wall‐less pathogen known to induce respiratory diseases in felines. Current research on respiratory M. felis infections is scant, lacking established typing system and nationwide epidemiological survey. This study investigated the prevalence of M.
Zijun Ye, Congrong Wang, Quanhui Yan, Weihui Li, Mingjun Ye, Yan Zhang, Luying Li, Qiuyan Li, Shengbo Cao, Yong-guo Cao   +9 more
wiley   +1 more source

Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species [PDF]

BMC Genomics, 2016
The genus Bordetella consists of nine species that include important respiratory pathogens such as the 'classical' species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and less extensively studied species. Here we analyze sequence diversity and gene content of 128 genome sequences from all nine species with focus ...
Linz, Bodo, Ivanov, Yury V., Preston, Andrew, Brinkac, Lauren, Parkhill, Julian, Kim, Maria, Harris, Simon R., Goodfield, Laura L., Fry, Norman K., Gorringe, Andrew R., Nicholson, Tracy L., Register, Karen B., Losada, Liliana, Harvill, Eric T.   +13 more
openaire   +3 more sources

A Deep Metagenomic Snapshot as a Proof‐of‐Concept for Resource Generation: Simultaneous Assembly of Host, Food, and Microbiome Genomes From Stingless Bee Larval Food

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study serves as a proof‐of‐concept, demonstrating that deep shotgun sequencing of a single complex sample—stingless bee larval food—can simultaneously generate multiple genomic resources. From this dataset, we assembled three genomes (a near‐complete bacterium, a draft host mitochondrion, and a fragmented plant chloroplast) with varying ...
Carlos Ueira‐Vieira, Ana Carolina Costa Santos, Thayane Nogueira Araújo, Solange Cristina Augusto, Natanael Borges de Avila, Ana Maria Bonetti, Anderson Rodrigues dos Santos   +6 more
wiley   +1 more source