Results 71 to 80 of about 13,827 (215)

Differential and Temporal Immunomodulation of alpha4 Integrins on CD4+ Memory Cells by Bordetella pertussis and Bordetella parapertussis [PDF]

, 2012
Pertussis, caused by Bordetella pertussis (B. pertussis), is reemerging worldwide due to vaccine inefficacy. The hallmarks of infection are extreme lymphocytosis and delayed recovery, which are partially associated with pertussis toxin.
Ravindra, Dipti
core   +1 more source

Regulation of Protein Secretion Systems Mediated by Cyclic Diguanylate in Plant-Interacting Bacteria [PDF]

, 2019
The ubiquitous second messenger cyclic diguanylate (c-di-GMP) is involved in the regulation of different processes in bacteria. In phytopathogens, intracellular fluctuations in the concentration of this molecule contribute to the lifestyle switching from
López Baena, Francisco Javier, Medina Morillas, Carlos, Vinardell González, José María   +2 more
core   +1 more source

The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model.

PLoS Pathogens, 2022
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in characterization of B. pertussis virulence mechanisms.
Jana Holubova, Ondrej Stanek, Attila Juhasz, Illiassou Hamidou Soumana, Peter Makovicky, Peter Sebo   +5 more
doaj   +1 more source

Chronic Productive Cough in an Immunosuppressed Patient due to Biologics: A Rare Case of Bordetella bronchiseptica Pulmonary Infection

Respirology Case Reports, Volume 14, Issue 1, January 2026.
This case illustrates features of ground glass changes on radiology in a patient who was immunosuppressed with biologics. Microbiology confirmed infection with Bordetella bronchiseptica, highlighting the importance of looking for atypical infections in patients receiving biologics and the importance of pet ownership history.
Debashree Banerjee, Eman Ayaz, Abby Hudson, Eamonn Trainor, Bavithra Vijayakumar, Harshana Bandara   +5 more
wiley   +1 more source

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Toxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez, Thibaut Douché, Mélody Dazas, Sophie Delaplane, Mariette Matondo, Julia Chamot-Rooke, Nicole Guiso   +6 more
doaj   +1 more source

The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System. [PDF]

PLoS ONE, 2015
Bordetella bronchiseptica is genetically related to B. pertussis and B. parapertussis, which cause respiratory tract infections in humans. These pathogens possess a large number of virulence factors, including the type III secretion system (T3SS), which ...
Akio Abe, Ryutaro Nishimura, Naomichi Tanaka, Jun Kurushima, Asaomi Kuwae   +4 more
doaj   +1 more source

Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains [PDF]

, 2007
BACKGROUND: Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to
Allison Kang, Becky Drees, Byron Gallis, Christine Fong, Colin Manoil, Danielle Buckley, David A D'Argenio, David R Goodlett, Don Guenthener, Donald Bovee, Eric Haugen, Greg Taylor, Hillary S Hayden, Jean Chang, Jinzhi Chen, Kerstin Svensson, Larry A Gallagher, Laurence Rohmer, Mats Forsman, Matthew Radey, Maynard V Olson, Michael Jacobs, Michael Wasnick, Mitchell J Brittnacher, Rajinder Kaul, Regina Lim, Robert K Ernst, Ruth Levy, Samuel I Miller, Scott A Shaffer, Simone Abmayr, Theodore Larson Freeman, Tina Guina, Will Gillett, Yang Zhou   +34 more
core   +2 more sources

Variation in the Bordetella pertussis Virulence Factors Pertussis Toxin and Pertactin in Vaccine Strains and Clinical Isolates in Finland [PDF]

Infection and Immunity, 1999
ABSTRACT There is evidence that pertussis is reemerging in vaccinated populations. We have proposed, and provided evidence for, one explanation for this phenomenon in The Netherlands: antigenic divergence between vaccine strains and circulating strains.
Mooi, FR, He, Q, van Oirschot, H, Mertsola, J   +3 more
openaire   +4 more sources

Metagenomic and Phenotypic Insights Into Biofilm‐Forming Pathogens in Patients With Nosocomial Sepsis

BioMed Research International, Volume 2026, Issue 1, 2026.
Biofilm‐related infections significantly contribute to bacterial diseases, with estimates suggesting that at least 80% of such infections are associated with biofilms. These infections often involve opportunistic pathogens, which not only influence the type of infection but also impact the microenvironment by interacting with other polymicrobial ...
Haleema Sadia, Arshia Amin, Iftikhar Ahmed, Baisakhi Banerjee   +3 more
wiley   +1 more source

New Data on Vaccine Antigen Deficient Bordetella pertussis Isolates

Vaccines, 2015
Evolution of Bordetella pertussis is driven by natural and vaccine pressures. Isolates circulating in regions with high vaccination coverage present multiple allelic and antigenic variations as compared to isolates collected before introduction of ...
Valérie Bouchez, Nicolas Hegerle, Francesco Strati, Elisabeth Njamkepo, Nicole Guiso   +4 more
doaj   +1 more source