Results 181 to 190 of about 46,694 (224)
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The detoxification of Bordetella pertussis with glutaraldehyde
Journal of Biological Standardization, 1987To improve the whole-cell pertussis vaccine we have studied the inactivation of the biological properties characteristic of Bordetella pertussis phase I bacteria, i.e. histamine-sensitizing, lymphocytosis-promoting and mouse protective activities, by treating a concentrated bacterial suspension with various concentrations of glutaraldehyde.
T, Iida, Y, Horiuchi
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Pertussis in the Era of New Strains of Bordetella pertussis
Infectious Disease Clinics of North America, 2015Despite implementation of a successful vaccination program, pertussis remains a significant health problem. Although the incidence of pertussis in the United States is reduced by approximately 80% compared with incidence before the introduction of vaccination in the 1940s, deaths still occur and the unrecognized disease burden remains high, with 1 ...
Emily, Souder, Sarah S, Long
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Pertussis toxin (Bordetella pertussis)
1997Abstract PT (Sekura et al. 1985) is a protein of 105 000 daltons composed of five noncovalently linked subunits named 51 through 55, and organized into two functional domains called A and B (Tamura et al. 1982). The A domain, which is composed of the 51 subunit, is an enzyme that intoxicates eukaryotic cells by ADP-ribosylating their GTP¬
R Rappuoli, M G Pizza
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Bordetella pertussis and Bordetella parapertussis
2010Nasopharyngeal aspirates, nasal swabs or throat swabs may be processed for Bordetella pertussis/parapertussis detection. Sputum, endotracheal tube aspirates, and BAL fluids are also occasionally processed for B. pertussis/parapertussis detection.
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Virulence factors of Bordetella pertussis
Antonie van Leeuwenhoek, 1988Clearly, B. pertussis has evolved very elaborate mechanisms to maintain itself in the human host. Three different proteins (FHA, pertussis toxin and fimbriae) have been implicated in adherence. Furthermore, a number of toxins are produced (pertussis toxin, adenylate cyclase, dermonecrotic toxin, and tracheal cytotoxin) which destroy the clearance ...
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Bordetella pertussis (Pertussis) and Other Bordetella Species
2012Long, SS, Edwards, KM, Mertsola, J
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Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host
Virulence, 2021Thomas Belcher +2 more
exaly
Genomic dissection of the microevolution of Australian epidemic Bordetella pertussis
Emerging Microbes and Infections, 2022Zheng Xu +2 more
exaly