Results 31 to 40 of about 94,944 (270)

Macrolide-Resistant Bordetella pertussis, Vietnam, 2016−2017

open access: yesEmerging Infectious Diseases, 2020
Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016−2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA.
K. Kamachi   +8 more
semanticscholar   +1 more source

Immunization with whole cell but not acellular pertussis vaccines primes CD4 TRM cells that sustain protective immunity against nasal colonization with Bordetella pertussis

open access: yesEmerging Microbes and Infections, 2019
Protective immunity wanes rapidly after immunization of children with acellular pertussis (aP) vaccines and these vaccines do not prevent nasal colonization or transmission of Bordetella pertussis in baboons. In this study, we examined the role of tissue-
Mieszko M. Wilk   +5 more
semanticscholar   +1 more source

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue

open access: yesbioRxiv, 2020
Bordetella bronchiseptica and Bordetella pertussis are closely related respiratory pathogens that evolved from a common bacterial ancestor. While B. bronchiseptica has an environmental reservoir and mostly establishes chronic infections in a broad range ...
Jan Bayram   +9 more
semanticscholar   +1 more source

Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction.

open access: yesPLoS ONE, 2014
Bordetella holmesii, an emerging pathogen, can be misidentified as Bordetella pertussis by routine polymerase chain reaction (PCR). In some reports, up to 29% of the patients diagnosed with pertussis have in fact B.
Laure F Pittet   +8 more
doaj   +1 more source

Detection of opsonizing antibodies directed against a recently circulating Bordetella pertussis strain in paired plasma samples from symptomatic and recovered pertussis patients. [PDF]

open access: yes, 2018
Correlates of protection (CoPs) against the highly contagious respiratory disease whooping cough, caused by Bordetella pertussis, remain elusive. Characterizing the antibody response to this pathogen is essential towards identifying potential CoPs. Here,
Bonačić Marinović, Axel A.   +11 more
core   +7 more sources

Outer-Membrane-Vesicle-Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]

open access: yes, 2018
Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Bartel, Erika Belén   +8 more
core   +3 more sources

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015

open access: yesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019
Introduction Pertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN)-deficient Bordetella pertussis isolates has been found in these countries ...
A. Barkoff   +15 more
semanticscholar   +1 more source

A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including Pertactin Deficient Strains

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Pertussis is a respiratory infectious disease that has been resurged during the last decades. The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular pertussis (aP) vaccines that consist of a few antigens formulated ...
M. E. Zurita   +7 more
semanticscholar   +1 more source

A Newly Discovered Bordetella Species Carries a Transcriptionally Active CRISPR-Cas with a Small Cas9 Endonuclease [PDF]

open access: yes, 2015
Background Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (cas) are widely distributed among bacteria.
Dudley, Edward G.   +7 more
core   +2 more sources

Resurgence of Bordetella pertussis, including one macrolide-resistant isolate, France, 2024

open access: yesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
As other European countries, France is experiencing a resurgence of pertussis in 2024. Between 1 January and 31 May 2024, 5,616 (24.9%) positive Bordetella pertussis qPCR tests were identified, following a 3-year period of almost null incidence.
Carla Rodrigues   +41 more
semanticscholar   +1 more source

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