Results 21 to 30 of about 29,875 (183)

The Role of the Aceullular Pertussis Vaccine and the Comeback of 'Pertussis Pete'?

open access: yesCanadian Journal of Infectious Diseases, 2001
Pertussis or whooping cough is an acute infectious disease of the respiratory tract caused principally by Bordetella pertussis and less commonly by Bordetella parapertussis (1).
John M Conly, B Lynn Johnston
doaj   +1 more source

Detection of small RNAs in Bordetella pertussis and identification of a novel repeated genetic element

open access: yesBMC Genomics, 2011
Background Small bacterial RNAs (sRNAs) have been shown to participate in the regulation of gene expression and have been identified in numerous prokaryotic species. Some of them are involved in the regulation of virulence in pathogenic bacteria. So far,
Wulbrecht Bérénice   +7 more
doaj   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson   +4 more
wiley   +1 more source

Pertussis in the Association of Southeast Asian Nations: epidemiology and challenges

open access: yesInternational Journal of Infectious Diseases, 2019
Pertussis is a highly infectious respiratory disease caused by Bordetella pertussis. Infants and young children are particularly at risk of severe and life-threatening disease. Infectious older individuals may transmit Bordetella pertussis to unprotected
Usa Thisyakorn   +3 more
doaj   +1 more source

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain

open access: yesIranian Journal of Microbiology, 2020
Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati   +3 more
doaj   +1 more source

Comparison of Bordetella species identification among differing rt-PCR assays in the United States

open access: yesMicrobiology Spectrum
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole   +7 more
doaj   +1 more source

Seroprevalence of IgA and IgM antibodies to Bordetella pertussis in healthy Japanese donors: Assessment for the serological diagnosis of pertussis.

open access: yesPLoS ONE, 2019
Pertussis is a human respiratory infection caused by the gram-negative bacterium, Bordetella pertussis. To evaluate the pertussis burden and vaccine efficacy, diagnosis and epidemiological surveillance should be based on accurate and valid diagnostic ...
Rei Fumimoto   +6 more
doaj   +1 more source

Laboratory-based surveillance of pertussis using multitarget real-time PCR in Japan: evidence for Bordetella pertussis infection in preteens and teens

open access: yesNew Microbes and New Infections, 2015
Between January 2013 and December 2014, we conducted laboratory-based surveillance of pertussis using multitarget real-time PCR, which discriminates among Bordetella pertussis, Bordetella parapertussis, Bordetella holmesii and Mycoplasma pneumoniae.
K. Kamachi   +5 more
doaj   +1 more source

The Eukaryotic Host Factor 14-3-3 Inactivates Adenylate Cyclase Toxins of Bordetella bronchiseptica and B. parapertussis, but Not B. pertussis

open access: yesmBio, 2018
Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki   +8 more
doaj   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

open access: yesImmunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude   +2 more
wiley   +1 more source

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