Results 31 to 40 of about 29,875 (183)

Emergence of Bordetella holmesii–Associated Pertussis-Like Illness, Northern India, 2019–2023

Emerging Infectious Diseases
We investigated Bordetella holmesii and Bordetella pertussis in 935 suspected pertussis cases in northern India (2019–2023) using PCR and serology. B. holmesii showed increased prevalence in pertussis cases, particularly in older children, highlighting ...
Nishant Shekhar, Deepa Sharma, Surajit Chakraborty, Rajesh Kumar, Rajneesh Singh Rawat, Nirmal Kaundal, Pawan Kumar, Tigran Avagyan, Deeksha Chauhan, Neha Jain, Megha Sharma, Arun Kumar, Vikas Gautam   +12 more
doaj   +1 more source

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis

mBio, 2022
Bordetella produces an array of virulence factors, including the adenylate cyclase toxin (ACT), which is essential, immunogenic in humans, and highly conserved.
Andrea M. DiVenere, Dzifa Amengor, Rui P. Silva, Jory A. Goldsmith, Jason S. McLellan, Jennifer A. Maynard   +5 more
doaj   +1 more source

Phenotypic expression of the gene‐for‐gene interaction in plant pathogenic bacteria: An implication for resistance to bacterial diseases by plants

Agrosystems, Geosciences &Environment, Volume 9, Issue 3, September 2026.
Abstract Plant pathogenic bacteria cause massive losses in agriculture and damage to natural plant habitats. Bacterial pathogens not only reduce crop production, but they also reduce crop quality by releasing toxins into the environment. Pathogenic bacteria that invade plant tissues must overcome the plant's defense mechanisms. Plants possess an innate
Muluken Getahun, Zelalem Bekeko
wiley   +1 more source

Highlights of the 14th International Bordetella Symposium

mSphere
Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus Bordetella pertussis.
Kevin Munoz Navarrete, Kathryn M. Edwards, Kingston H. G. Mills, Jana Kamanová, María Eugenia Rodriguez, Andrew Gorringe, Andrew Preston, Beate Kampmann, Monica C. Gestal, Eric T. Harvill, Purnima Dubey, Dimitri A. Diavatopoulos, Seema Mattoo, Karen M. Scanlon, Camille Locht, Peter Sebo   +15 more
doaj   +1 more source

AF‐CALVADOS: AlphaFold‐guided simulations of multi‐domain proteins at the proteome level

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Deep‐learning methods have transformed our ability to predict the three‐dimensional structures of folded proteins from sequence, and coarse‐grained simulations have made it possible to study intrinsically disordered proteins at the proteome scale. More than half of human proteins, however, contain mixtures of disordered regions and one or more
Sören von Bülow, Kristoffer E. Johansson, Kresten Lindorff‐Larsen   +2 more
wiley   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, Volume 13, Issue 37, 3 July 2026.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Donor Pooling as an Effective Method to Increase MSC EV Production Without Compromising Therapeutic Potential

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Mesenchymal stromal cell extracellular vesicles (MSC EVs) hold great therapeutic potential. Their immunomodulatory abilities make them suitable candidates to treat autoimmune diseases, such as rheumatoid arthritis. However, MSC EV production must be reproducibly scaled to meet the demand of research and therapeutics.
Rebecca Davies, Claire Mennan, Anaïs Makos, Tian Lan, Charlotte Hulme, Mark Platt, Karina Wright, Oksana Kehoe   +7 more
wiley   +1 more source

A rapid and sensitive recombinase aided amplification assay incorporating competitive internal control to detect Bordetella pertussis using the DNA obtained by boiling

International Journal of Infectious Diseases, 2019
Objectives: Pertussis is a highly transmissible acute respiratory infection caused by the bacterial pathogen Bordetella pertussis. The purpose of this study was to develop a rapid, simple and sensitive diagnostic test for detecting this pathogen. Methods:
Rui-qing Zhang, Gui-xia Li, Xin-na Li, Xin-xin Shen, Yuan Gao, Le Wang, Tao Fan, Qing-xia Duan, Ya-kun Wang, Ji Wang, Zhi-shan Feng, Xue-jun Ma   +11 more
doaj   +1 more source

Characteristics and Risk Factors Associated With Hospitalization and Severe Disease in Patients Aged ≥ 60 Years With Human Metapneumovirus Infection Over Three Consecutive Seasons (2021–2024) in Valladolid, Spain. The VALLAVIRUS Study

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Human metapneumovirus (hMPV) is a respiratory pathogen often underestimated in the elderly. Although studies suggest it causes around 10% of respiratory hospitalizations in the United States, national and local data remain scarce.
Iván Sanz‐Muñoz, Silvia Galindo‐Carretero, Marina Toquero‐Asensio, Alejandro Martín‐Toribio, Raquel Iglesia‐Aparicio, Celia López‐Gonzalo, Diana Rodríguez‐González, Laura Tamayo‐Pérez, Javier Sánchez‐Martínez, Carla Rodríguez‐Crespo, Alberto Caballero‐García, Marta Domínguez‐Gil, Silvia Rojo‐Rello, José María Eiros   +13 more
wiley   +1 more source

Do not let perfect be the enemy of good: the current reality of Bordetella testing

Microbiology Spectrum
Diagnosis of Bordetella pertussis is made by using polymerase chain reaction (PCR) to detect insertion sequence 481 (IS481). However, IS481 is found in both B. pertussis and Bordetella holmesii. In a recent study, Cole et al.
Rebecca Yee
doaj   +1 more source