Results 41 to 50 of about 46,694 (224)

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain

Iranian Journal of Microbiology, 2020
Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati, Ashraf Mohabati Mobarez, Seyed Davar Siadat, Mojtaba Noofeli   +3 more
doaj   +1 more source

Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009–2015

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim of this study was to investigate the possible source of laboratory‐confirmed pertussis in infants under 6 months of age. Methods This nationwide prospective study was based on laboratory‐confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed
Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist   +4 more
wiley   +1 more source

Seroprevalence of IgA and IgM antibodies to Bordetella pertussis in healthy Japanese donors: Assessment for the serological diagnosis of pertussis.

PLoS ONE, 2019
Pertussis is a human respiratory infection caused by the gram-negative bacterium, Bordetella pertussis. To evaluate the pertussis burden and vaccine efficacy, diagnosis and epidemiological surveillance should be based on accurate and valid diagnostic ...
Rei Fumimoto, Nao Otsuka, Hajime Kamiya, Tomimasa Sunagawa, Keiko Tanaka-Taya, Kazunari Kamachi, Keigo Shibayama   +6 more
doaj   +1 more source

Analysis of Bordetella pertussis populations in European countries with different vaccination policies. [PDF]

, 2005
Despite the widespread use of pertussis vaccines during the last decades, pertussis has remained an endemic disease with frequent epidemic outbreaks. Currently two types of vaccines are used: whole-cell vaccines (WCVs) and recently developed acellular ...
Amersfoorth, S C M van, Schouls, L M, Heide, H G J van der, Advani, A, Hallander, H O, Bondeson, K, König, C H W von, Riffelmann, M, Vahrenholz, C, Guiso, N, Caro, V, Njamkepo, E, He, Q, Mertsola, J, Mooi, F R   +14 more
core   +1 more source

Comparison of Bordetella species identification among differing rt-PCR assays in the United States

Microbiology Spectrum
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole, Ashley K. Simon, Amanda Faulkner, Tami Skoff, Maria L. Tondella, Clemente Montero, Melinda B. Nye, Margaret Williams   +7 more
doaj   +1 more source

The Eukaryotic Host Factor 14-3-3 Inactivates Adenylate Cyclase Toxins of Bordetella bronchiseptica and B. parapertussis, but Not B. pertussis

mBio, 2018
Bordetella pertussis, Bordetella bronchiseptica, and Bordetella parapertussis share highly homologous virulence factors and commonly cause respiratory infections in mammals; however, their host specificities and disease severities differ, and the reasons
Aya Fukui-Miyazaki, Hirono Toshima, Yukihiro Hiramatsu, Keisuke Okada, Keiji Nakamura, Keisuke Ishigaki, Naoaki Shinzawa, Hiroyuki Abe, Yasuhiko Horiguchi   +8 more
doaj   +1 more source

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis

mBio, 2022
Bordetella produces an array of virulence factors, including the adenylate cyclase toxin (ACT), which is essential, immunogenic in humans, and highly conserved.
Andrea M. DiVenere, Dzifa Amengor, Rui P. Silva, Jory A. Goldsmith, Jason S. McLellan, Jennifer A. Maynard   +5 more
doaj   +1 more source

Laboratory-based surveillance of pertussis using multitarget real-time PCR in Japan: evidence for Bordetella pertussis infection in preteens and teens

New Microbes and New Infections, 2015
Between January 2013 and December 2014, we conducted laboratory-based surveillance of pertussis using multitarget real-time PCR, which discriminates among Bordetella pertussis, Bordetella parapertussis, Bordetella holmesii and Mycoplasma pneumoniae.
K. Kamachi, S. Yoshino, C. Katsukawa, N. Otsuka, Y. Hiramatsu, K. Shibayama   +5 more
doaj   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Highlights of the 14th International Bordetella Symposium

mSphere
Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus Bordetella pertussis.
Kevin Munoz Navarrete, Kathryn M. Edwards, Kingston H. G. Mills, Jana Kamanová, María Eugenia Rodriguez, Andrew Gorringe, Andrew Preston, Beate Kampmann, Monica C. Gestal, Eric T. Harvill, Purnima Dubey, Dimitri A. Diavatopoulos, Seema Mattoo, Karen M. Scanlon, Camille Locht, Peter Sebo   +15 more
doaj   +1 more source