Results 11 to 20 of about 4,643 (168)

Automatic detection of hippocampal sclerosis in patients with epilepsy. [PDF]

Epilepsia
Abstract Objective This study was undertaken to develop and validate an automatic, artificial intelligence‐enhanced software tool for hippocampal sclerosis (HS) detection, using a variety of standard magnetic resonance imaging (MRI) protocols from different MRI scanners for routine clinical practice.
Belke M, Zahnert F, Steinbrenner M, Halimeh M, Miron G, Tsalouchidou PE, Linka L, Keil B, Jansen A, Möschl V, Kemmling A, Nimsky C, Rosenow F, Menzler K, Knake S.   +14 more
europepmc   +2 more sources

The Double Legacy of Bernalism in Science Diplomacy. [PDF]

Ber Wiss, 2022
Abstract Recent debates in the history of science aimed at reconstructing the history of scientific diplomacy have privileged the analysis of forms of diplomacy coming from above. Instead, the objective of this paper is to raise awareness of these debates by looking at attempts at scientific diplomacy from below. Such a shift in perspective might allow
Ienna G.
europepmc   +2 more sources

A LEAP Forward in Wildlife Conservation: A Standardized Framework to Determine Mortality Causes in Large GPS-Tagged Birds. [PDF]

Ecol Evol
A novel framework for determining the causes of mortality of large GPS‐tagged birds, the LIFE EUROKITE Assessment Protocol (LEAP), was developed. LEAP integrates GPS tracking data, site investigation, and necropsy to derive mortality causes and a corresponding certainty score. Two case studies demonstrated improvements in mortality assessments compared
Panter CT, Nebel C, Raab M, Strauss V, Freytag C, Wojta M, Böing H, Hacker P, Raab R, Windt J, Posautz A, Kuebber-Heiss A, Scherler P, Grüebler MU, Kormann UG, Kolbe M, Millon A, de la Puente J, Viñuela J, Orr-Ewing D, Krone O, Langgemach T, Åkesson S, Mattsson B, Sumasgutner P, Alcántara de la Fuente M, Alvarez E, Arizaga J, Bach Pagès A, Bermejo A, Ceccolini G, Chakarov N, Derpmann-Hagenström P, Dostál M, Fabian G, Fiedler W, Galán M, Ganier C, Gärtner A, Glesener L, Godino A, Guziová Z, Haraszthy L, Karlsson C, Klein K, Literák I, Lorenzini N, Löwold M, Lüning C, Maderič B, Makoň K, Mammen K, Mammen U, Marczak T, Matušík H, Mionnet A, Morollón S, Mráz J, Nachtigall W, Nicolai B, Olalde Fernández M, Ottensmann M, Palacios González MJ, Paquet JY, Pečeňák V, Peške L, Pfeiffer T, Pudwill R, Rak D, Rapp TM, Resetaritz A, van Rijn S, Riols R, Rodríguez A, Scholze L, Schulte L, de Seynes A, Škrábal J, Spakovszky P, Steinborn E, Svetlík J, Talhoet S, Vaczi M, Verdier AG, Vermouzek Z, Villanúa Inglada D, Westphal J, Raab R.   +87 more
europepmc   +2 more sources

Authority Claims Situating Socialist Science Studies in the GDR*. [PDF]

Ber Wiss, 2021
Abstract This essay studies the narrative self‐positioning of Science Studies in the German Democratic Republic during the 1980s. Drawing on archival material on the foundation of the Council for Marxist‐Leninist Science Studies at the Academy of Sciences in East Berlin in March 1988, it analyses how boundaries between Science Studies as a lone ...
Cain F.
europepmc   +2 more sources

The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms. [PDF]

BMC Cancer, 2016
Background: Dual specificity phosphatases are a class of tumor-associated proteins involved in the negative regulation of the MAP kinase pathway. Downregulation of the dual specificity phosphatase 2 (DUSP2) has been reported in cancer.
Haag T, Richter AM, Schneider MB, Jiménez AP, Dammann RH.   +4 more
europepmc   +4 more sources

Comprehensive Fragment Screening of the SARS‐CoV‐2 Proteome Explores Novel Chemical Space for Drug Development

Angewandte Chemie, Volume 134, Issue 46, November 14, 2022., 2022
Using a fragment‐based screening strategy by NMR, we identified 311 small molecule binders of 25 SARS‐CoV‐2 proteins, thus expanding the previously unexplored chemical and target space. Further, using experimental and bioinformatic analysis we identify potential binding sites.
Hannes Berg, Maria A. Wirtz Martin, Nadide Altincekic, Islam Alshamleh, Jasleen Kaur Bains, Julius Blechar, Betül Ceylan, Vanessa de Jesus, Karthikeyan Dhamotharan, Christin Fuks, Santosh L. Gande, Bruno Hargittay, Katharina F. Hohmann, Marie T. Hutchison, Sophie Marianne Korn, Robin Krishnathas, Felicitas Kutz, Verena Linhard, Tobias Matzel, Nathalie Meiser, Anna Niesteruk, Dennis J. Pyper, Linda Schulte, Sven Trucks, Kamal Azzaoui, Marcel J. J. Blommers, Yojana Gadiya, Reagon Karki, Andrea Zaliani, Philip Gribbon, Marcius da Silva Almeida, Cristiane Dinis Anobom, Anna L. Bula, Matthias Bütikofer, Ícaro Putinhon Caruso, Isabella Caterina Felli, Andrea T. Da Poian, Gisele Cardoso de Amorim, Nikolaos K. Fourkiotis, Angelo Gallo, Dhiman Ghosh, Francisco Gomes‐Neto, Oksana Gorbatyuk, Bing Hao, Vilius Kurauskas, Lauriane Lecoq, Yunfeng Li, Nathane Cunha Mebus‐Antunes, Miguel Mompeán, Thais Cristtina Neves‐Martins, Martí Ninot‐Pedrosa, Anderson S. Pinheiro, Letizia Pontoriero, Yulia Pustovalova, Roland Riek, Angus J. Robertson, Marie Jose Abi Saad, Miguel Á. Treviño, Aikaterini C. Tsika, Fabio C. L. Almeida, Ad Bax, Katherine Henzler‐Wildman, Jeffrey C. Hoch, Kristaps Jaudzems, Douglas V. Laurents, Julien Orts, Roberta Pierattelli, Georgios A. Spyroulias, Elke Duchardt‐Ferner, Jan Ferner, Boris Fürtig, Martin Hengesbach, Frank Löhr, Nusrat Qureshi, Christian Richter, Krishna Saxena, Andreas Schlundt, Sridhar Sreeramulu, Anna Wacker, Julia E. Weigand, Julia Wirmer‐Bartoschek, Jens Wöhnert, Harald Schwalbe   +82 more
wiley   +2 more sources

Bausteine zu einer Oral History der Wissenschaftsgeschichte Interview mit Dieter Hoffmann

Berichte zur Wissenschaftsgeschichte, Volume 46, Issue 4, Page 378-412, December 2023., 2023
Abstract Wie kann man einen historischen Blick auf das eigene Fach werfen? Diese Frage ist nicht einfach zu beantworten – will man einerseits nicht in einer Nabelschau und Hagiographie enden, andererseits aber auch keinen umfassenden Entwurf einer zukünftigen Historiographie vorlegen.
Mathias Grote, Anke te Heesen, Dieter Hoffmann   +2 more
wiley   +1 more source

Site‐Specific Labeling of RNAs with Modified and 19F‐Labeled Nucleotides by Chemo‐Enzymatic Synthesis

Chemistry – A European Journal, Volume 29, Issue 25, May 2, 2023., 2023
A library of post‐transcriptional modifications and synthetic modified nucleosides for the site‐specific alteration of RNAs applying a chemo‐enzymatic method is presented. This method overcomes the limitations of other established and well‐known RNA synthesis techniques.
Alexey Sudakov, Bozana Knezic, Martin Hengesbach, Boris Fürtig, Elke Stirnal, Harald Schwalbe   +5 more
wiley   +1 more source

Das COVID19‐NMR‐Konsortium: Ein öffentlicher Bericht über den Einfluss dieser neuen globalen Kollaboration

Angewandte Chemie, Volume 135, Issue 14, March 27, 2023., 2023
Dieser Viewpoint Article beschreibt die Selbstorganisation der weltweiten NMR‐Gemeinschaft, um einen zeitnahen Beitrag zur Bekämpfung von SARS‐CoV‐2 zu leisten. Diese neue Art der kollaborativen Forschung könnte als Modell für die Bewältigung weiterer aktueller und künftiger großer gesellschaftlicher Bedürfnisse dienen, ohne dabei mit ...
Elke Duchardt‐Ferner, Jan Ferner, Boris Fürtig, Martin Hengesbach, Christian Richter, Andreas Schlundt, Sridhar Sreeramulu, Anna Wacker, Julia E. Weigand, Julia Wirmer‐Bartoschek, Harald Schwalbe   +10 more
wiley   +1 more source

The COVID19‐NMR Consortium: A Public Report on the Impact of this New Global Collaboration

Angewandte Chemie International Edition, Volume 62, Issue 14, March 27, 2023., 2023
This Viewpoint Article discusses how the global NMR community organized itself to rapidly contribute to combat SARS‐CoV‐2. This new collaborative research might serve as model for future ways to address great societal needs, without competing with curiosity‐driven research.
Elke Duchardt‐Ferner, Jan Ferner, Boris Fürtig, Martin Hengesbach, Christian Richter, Andreas Schlundt, Sridhar Sreeramulu, Anna Wacker, Julia E. Weigand, Julia Wirmer‐Bartoschek, Harald Schwalbe   +10 more
wiley   +1 more source