Results 1 to 10 of about 126,053 (159)

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies [PDF]

open access: yesJournal of Hematology & Oncology
Background Small molecule inhibition of BCL-XL with navitoclax resulted in on-target dose-limiting thrombocytopenia. DT2216 was more effective than navitoclax and reduced platelet toxicity in preclinical models by selectively degrading BCL-XL via the VHL
Daruka Mahadevan   +14 more
doaj   +2 more sources

RoCo: Dialectic Multi-Robot Collaboration with Large Language Models [PDF]

open access: yesIEEE International Conference on Robotics and Automation, 2023
We propose a novel approach to multi-robot collaboration that harnesses the power of pre-trained large language models (LLMs) for both high-level communication and low-level path planning.
Man-Di Zhao, Shreeya Jain, Shu-Ran Song
semanticscholar   +1 more source

Dialectics and dilemmas arising from Covid-19 immunity testing: presenting a workforce management paradox [PDF]

open access: yesJournal of Work-Applied Management, 2021
Purpose – Covid-19 has caused many businesses to rethink their short- and potentially long-term workforce operations. The use of lateral flow serology can provide a clinically convenient approach for the assessment of prior infection with Covid-19 ...
Steven Davies   +3 more
doaj   +1 more source

Determining and Grounding: The Twofold Function of the Transcendental Dialectic

open access: yesOpen Philosophy, 2022
For a long time, the transcendental dialectic was not at the center of Kant scholarship but was often treated simply as Kant’s reckoning with contemporary metaphysics.
Bunte Martin
doaj   +1 more source

Fede, ragione e il principio di non-contraddizione in Pier Damiani

open access: yesNoctua, 2021
In literature Peter Damian has been often presented as an anti-dialectic thinker. Over time this statement has been subjected to careful historiographical revision.
Fabrizio Amerini
doaj   +1 more source

An Opuscule on Method, or how Philosophers Mark out Textually their Methodo- logical Stance (a Text Following up a Text)

open access: yesНаукові записки НаУКМА: Філософія та релігієзнавство, 2021
The present paper is a practical supplement to an earlier theoretical work by the author, published in a preceding issue, on methodological foundations of the European philosophizing in the aspect of sophical synthesis.
Yuriy Svatko
doaj   +1 more source

The dialectic of democracy: modernization, emancipation and the great regression

open access: yesDemocratization, 2020
In some of the most established and supposedly immutable liberal democracies, diverse social groups are losing confidence not only in established democratic institutions, but in the idea of liberal representative democracy itself. Meanwhile, an illiberal
I. Blühdorn
semanticscholar   +1 more source

Dialectic and Refutation in Plato. On the Role of Refutation in the Search for Truth

open access: yesArchai: Revista de Estudos sobre as Origens do Pensamento Ocidental, 2022
While refutation is usually related to Plato's early, Socratic, dialogues, this paper is aimed at exploring the link between refutation and dialectic in some of his middle and late dialogues.
Graciela Marcos
doaj   +1 more source

Dialectic and Refutation in Plato and Aristotle

open access: yesArchai: Revista de Estudos sobre as Origens do Pensamento Ocidental, 2022
The papers in this dossier were written within the framework of two research projects on the refutation strategies of radical adversaries in Plato’s and Aristotle’s writings.
Pilar Spangenberg
doaj   +1 more source

The Effect of Health on Human’s Moral Identity from Avicenna’s Point of View (Focusing on Exercise, Nutrition, and Sleep) [PDF]

open access: yesPizhūhish/hā-yi Falsafī- Kalāmī
Moral identity refers to those characteristics and attributes that play an important role in the formation of an individual’s identity. Indeed, the role performed by moral attributes in the evolution of a person’s identity is such that quite a few of ...
Aysooda Hashempur, Forough Rahimpoor
doaj   +1 more source

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