Results 11 to 20 of about 7,855 (167)
First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies. [PDF]
Background Small molecule inhibition of BCL-XL with navitoclax resulted in on-target dose-limiting thrombocytopenia. DT2216 was more effective than navitoclax and reduced platelet toxicity in preclinical models by selectively degrading BCL-XL via the VHL
Mahadevan D +14 more
europepmc +2 more sources
Dialectics and dilemmas arising from Covid-19 immunity testing: presenting a workforce management paradox [PDF]
Purpose – Covid-19 has caused many businesses to rethink their short- and potentially long-term workforce operations. The use of lateral flow serology can provide a clinically convenient approach for the assessment of prior infection with Covid-19 ...
Steven Davies +3 more
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Determining and Grounding: The Twofold Function of the Transcendental Dialectic
For a long time, the transcendental dialectic was not at the center of Kant scholarship but was often treated simply as Kant’s reckoning with contemporary metaphysics.
Bunte Martin
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Fede, ragione e il principio di non-contraddizione in Pier Damiani
In literature Peter Damian has been often presented as an anti-dialectic thinker. Over time this statement has been subjected to careful historiographical revision.
Fabrizio Amerini
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The present paper is a practical supplement to an earlier theoretical work by the author, published in a preceding issue, on methodological foundations of the European philosophizing in the aspect of sophical synthesis.
Yuriy Svatko
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Dialectic and Refutation in Plato. On the Role of Refutation in the Search for Truth
While refutation is usually related to Plato's early, Socratic, dialogues, this paper is aimed at exploring the link between refutation and dialectic in some of his middle and late dialogues.
Graciela Marcos
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Dialectic and Refutation in Plato and Aristotle
The papers in this dossier were written within the framework of two research projects on the refutation strategies of radical adversaries in Plato’s and Aristotle’s writings.
Pilar Spangenberg
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The Effect of Health on Human’s Moral Identity from Avicenna’s Point of View (Focusing on Exercise, Nutrition, and Sleep) [PDF]
Moral identity refers to those characteristics and attributes that play an important role in the formation of an individual’s identity. Indeed, the role performed by moral attributes in the evolution of a person’s identity is such that quite a few of ...
Aysooda Hashempur, Forough Rahimpoor
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Este trabalho objetiva caracterizar a lógica e a dialética, conforme a Enéada I, 3 [20] 4-5. Para Plotino, a lógica consiste em um conjunto de procedimentos que trata de proposições e silogismos.
Loraine Oliveira
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Aristotle’s Topics in the Greek Neoplatonic Commentaries on the Categories
This paper lists and examines the explicit references to Aristotle’s Topics in the Greek Neoplatonic commentaries on the Categories. The references to the Topics by Porphyry, Dexippus, Ammonius, Simplicius, Olympiodorus, Philoponus and David (Elias) are ...
Chiara Militello
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