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Borna disease virus

Emerging Infectious Diseases, 2009
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Borna Disease in Horses

Veterinary Clinics of North America: Equine Practice, 2000
Borna disease is a sporadically occurring, progressive viral polioencephalomyelitis that primarily affects horses and sheep. The etiological agent, Borna disease virus (BDV), is an enveloped, single-stranded RNA virus that has been classified in the new virus family Bornaviridae within the order Mononegavirales.
J A, Richt, A, Grabner, S, Herzog
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Borna Disease Virus

Journal of Neurovirology, 2002
Borna disease virus, a negative-strand RNA virus, infects a wide variety of warm-blooded animals. Depending on the age of the host and the integrity of its immune response, infection may be asymptomatic or cause a broad spectrum of behavioral disorders.
Mady, Hornig, Thomas, Briese, W Ian, Lipkin   +2 more
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Neurotransmitter abnormalities in Borna disease

Brain Research, 1988
Borna disease (BD) agent is an infectious pathogen that causes progressive central nervous system (CNS) dysfunction in a wide range of vertebrate hosts. The course of BD in adult rats is biphasic. The acute phase is characterized by aggressive behavior and inflammatory cell infiltrates in brain.
W I, Lipkin, K M, Carbone, M C, Wilson, C S, Duchala, O, Narayan, M B, Oldstone   +5 more
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Dementia and Borna Disease Virus

Dementia and Geriatric Cognitive Disorders, 1997
Human Borna disease virus (BDV) infection has been reported to be a threat to mental health [1]. BDV is an unclassified, nonsegmented negative sense single-stranded RNA virus which naturally infects horses, cattle, cats and sheep [2, 3]. Infection causes disturbances in behavior and cognitive function [1].
T, Igata, K, Yamaguchi, R, Igata-Yi, K, Yoshiki, S, Takemoto, H, Yamasaki, M, Matuoka, T, Miyakawa   +7 more
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Immunopathogenesis of Borna Disease

1995
Diseases of the central nervous system are fearsome conditions due to their deleterious effects on physical and mental functions. In addition to acute diseases caused by viruses and bacteria infecting the meninges and the brain, disturbances of motility, disorders in sensory functions, behavioral abnormalities, personality changes and chronic debility ...
L, Stitz, B, Dietzschold, K M, Carbone
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Borna disease virus and schizophrenia

Psychiatry Research, 1995
The development of a new serological assay method to detect antibodies in human sera recognizing Borna disease virus (BDV) proteins and a clinical pilot study are presented. Psychiatric patients from a schizophrenia research clinic in Baltimore, Maryland, were examined for antibodies to BDV antigen with traditional indirect immunofluorescence assays ...
R W, Waltrip, R W, Buchanan, A, Summerfelt, A, Breier, W T, Carpenter, N L, Bryant, S A, Rubin, K M, Carbone   +7 more
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Borna—A slow virus disease

Comparative Immunology, Microbiology and Infectious Diseases, 1978
Abstract Borna is an ideal model for the study of the pathogenesis of slow virus diseases. Our present knowledge of the nature of the agent, the immunology, the pathogenesis, the different courses of infection and diagnosis is described. The wide host and cell spectrum of Borna virus leads one to suppose that Borna infections are more widespread ...
A, Mayr, K, Danner
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Borna Disease in a Dog in Japan

Journal of Comparative Pathology, 2002
Borna disease (BD) was diagnosed in a 3-year-old male Welsh corgi suffering from a severe and acute progressive disorder of the central nervous system. Histopathologically, neuronal lesions were characterized by a non-suppurative encephalomyelitis dominated by large perivascular cuffs consisting of lymphocytes, macrophages and plasma cells; also ...
M, Okamoto, Y, Kagawa, W, Kamitani, K, Hagiwara, R, Kirisawa, H, Iwai, K, Ikuta, H, Taniyama   +7 more
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Borna disease virus is not sensitive to amantadine

Archives of Virology, 1997
Successful inhibition of Borna disease virus (BDV) by amantadine in cultured cells and in an infected human individual has been reported [Bode et al. (1997) Lancet 349: 178-179]. We now found that infection of monkey Vero cells by laboratory strains of BDV was not influenced by amantadine under conditions that reduced the yields of influenza A virus by
Hallensleben, Wiebke, Zocher, Marcel, Stäheli, Peter   +2 more
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