Results 151 to 160 of about 4,924 (198)

Neurotransmitter abnormalities in Borna disease

Brain Research, 1988
Borna disease (BD) agent is an infectious pathogen that causes progressive central nervous system (CNS) dysfunction in a wide range of vertebrate hosts. The course of BD in adult rats is biphasic. The acute phase is characterized by aggressive behavior and inflammatory cell infiltrates in brain.
W I, Lipkin, K M, Carbone, M C, Wilson, C S, Duchala, O, Narayan, M B, Oldstone   +5 more
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Immunopathogenesis of Borna Disease

1995
Diseases of the central nervous system are fearsome conditions due to their deleterious effects on physical and mental functions. In addition to acute diseases caused by viruses and bacteria infecting the meninges and the brain, disturbances of motility, disorders in sensory functions, behavioral abnormalities, personality changes and chronic debility ...
L, Stitz, B, Dietzschold, K M, Carbone
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Dementia and Borna Disease Virus

Dementia and Geriatric Cognitive Disorders, 1997
Human Borna disease virus (BDV) infection has been reported to be a threat to mental health [1]. BDV is an unclassified, nonsegmented negative sense single-stranded RNA virus which naturally infects horses, cattle, cats and sheep [2, 3]. Infection causes disturbances in behavior and cognitive function [1].
T, Igata, K, Yamaguchi, R, Igata-Yi, K, Yoshiki, S, Takemoto, H, Yamasaki, M, Matuoka, T, Miyakawa   +7 more
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Borna disease virus and schizophrenia

Psychiatry Research, 1995
The development of a new serological assay method to detect antibodies in human sera recognizing Borna disease virus (BDV) proteins and a clinical pilot study are presented. Psychiatric patients from a schizophrenia research clinic in Baltimore, Maryland, were examined for antibodies to BDV antigen with traditional indirect immunofluorescence assays ...
R W, Waltrip, R W, Buchanan, A, Summerfelt, A, Breier, W T, Carpenter, N L, Bryant, S A, Rubin, K M, Carbone   +7 more
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Borna—A slow virus disease

Comparative Immunology, Microbiology and Infectious Diseases, 1978
Abstract Borna is an ideal model for the study of the pathogenesis of slow virus diseases. Our present knowledge of the nature of the agent, the immunology, the pathogenesis, the different courses of infection and diagnosis is described. The wide host and cell spectrum of Borna virus leads one to suppose that Borna infections are more widespread ...
A, Mayr, K, Danner
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Borna Disease in a Dog in Japan

Journal of Comparative Pathology, 2002
Borna disease (BD) was diagnosed in a 3-year-old male Welsh corgi suffering from a severe and acute progressive disorder of the central nervous system. Histopathologically, neuronal lesions were characterized by a non-suppurative encephalomyelitis dominated by large perivascular cuffs consisting of lymphocytes, macrophages and plasma cells; also ...
M, Okamoto, Y, Kagawa, W, Kamitani, K, Hagiwara, R, Kirisawa, H, Iwai, K, Ikuta, H, Taniyama   +7 more
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Immune-Mediated Pathogenesis of Borna Disease

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology, 1988
Borna disease is an endemic progressive encephalomyelitis of horses and sheep prevalent in central Europe. A wide variety of animal species, ranging from chickens to primates can be infected experimentally with the causative virus, which is only poorly characterized. Furthermore, BD virus-specific antibodies have been detected in sera and cerebrospinal
R, Rott, S, Herzog, J, Richt, L, Stitz
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Borna disease virus and infection in humans

Frontiers in Bioscience, 2002
Borna disease virus (BDV) is a nonsegmented, negative-, single-stranded, highly neurotropic RNA virus with noncytolytic replication in the central nervous system. This virus causes neurological and behavioral disturbances primarily in horses and sheep, in addition to a variety of other vertebrate animal species and in laboratory animal models.
Kazuyoshi, Ikuta, Madiha S, Ibrahim, Takeshi, Kobayashi, Keizo, Tomonaga   +3 more
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Borna disease virus is not sensitive to amantadine

Archives of Virology, 1997
Successful inhibition of Borna disease virus (BDV) by amantadine in cultured cells and in an infected human individual has been reported [Bode et al. (1997) Lancet 349: 178-179]. We now found that infection of monkey Vero cells by laboratory strains of BDV was not influenced by amantadine under conditions that reduced the yields of influenza A virus by
Hallensleben, Wiebke, Zocher, Marcel, Stäheli, Peter   +2 more
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[Borna disease].

Immunitat und Infektion, 1989
Using Borna disease as a model, the consequences of persistent virus infections of the central nervous system, in particular of "slow virus diseases", are briefly described. Both latent and active forms of the disease have much in common with chronically progressive diseases of the central nervous system in animals and man which have until now remained
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