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Borna disease virus and infection in humans
Frontiers in Bioscience, 2002Borna disease virus (BDV) is a nonsegmented, negative-, single-stranded, highly neurotropic RNA virus with noncytolytic replication in the central nervous system. This virus causes neurological and behavioral disturbances primarily in horses and sheep, in addition to a variety of other vertebrate animal species and in laboratory animal models.
Kazuyoshi, Ikuta +3 more
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Activated Borna Disease Virus in Affective Disorders
Pharmacopsychiatry, 1999Borna disease virus (BDV) is an animal pathogen that causes behavioral changes in animals. Previous studies have found a high prevalence of serum antibodies as well as Borna disease viral antigens (BDVAGs) and RNA in the white blood cells of psychiatric patients, especially those with affective disorders.
R, Ferszt +6 more
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Fatal Encephalitic Borna Disease Virus 1 in Solid-Organ Transplant Recipients.
New England Journal of Medicine, 2018Fatal Zoonotic Viral Infection after Transplantation Evidence of Borna disease virus 1 infection in humans is limited; in this report, donor-derived Borna virus encephalitis is shown to occur in three solid-organ transplant recipients.
Kore Schlottau +34 more
semanticscholar +1 more source
Borna Disease Virus infection in young children
APMIS, 2008Borna Disease Virus infection (BDV) is a well known animal disease. It got its name from a disease outbreak among horses around the small town ‘‘Borna’’, 26 km south-east of Leipzig in the late 19th century. The symptoms in horses have been described in detail and involve neurologic as well as mental and behavioral disorders.
Thomas, Scholbach, Liv, Bode
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Borna Disease Virus Molecular Virology
2014Borna disease virus (BDV) infectivity and RNA have been detected in bodily secretions and excretions, suggesting that BDV can be transmitted through salival, nasal, and conjunctival secretions and, particularly, urine and feces. BDV infection produces a range of phenotypic disease expression. BDV has a non-segmented, negative-stranded (NNS) RNA genome.
Masahiko Kishi +3 more
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Human Borna Disease Virus Infection
2014A study to find borna disease (BD) virus (BDV)-specific serum antibodies in psychiatric patients with major depression but not in healthy controls suggested a possible causal relationship between BDV infection and depressive disorders. Serological assay including such as IFA, WBA and ELISA are discussed.
Oliver Planz +2 more
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Borna disease virus and depression
Trends in Microbiology, 2001High amounts of circulating immune complexes of Borna disease virus correlates with severity of depression, according to Dr Liv Bode of the Robert Koch-Institut in Berlin, Germany. The virus targets limbic structure neurons and is known to cause behavioral abnormalities in animals.
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Cerebrospinal fluid in Borna disease virus 1 (BoDV-1) encephalitis
Journal of Neurological Sciences, 2023Bernhard Neumann +16 more
semanticscholar +1 more source
Borna Disease (Borna Disease Virus-1, BoDV-1)
2023Merle M. Böhmer, Markus Bauswein
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Does Borna disease virus infect humans?
Nature Medicine, 1995Borna virus causes neurological disease in animals. It may be responsible for human disorders as well (pp. 232–236).
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