Organosilica nanoparticles containing sodium borocaptate (BSH) provide new prospects for boron neutron capture therapy (BNCT): efficient cellular uptake and enhanced BNCT efficacy. [PDF]
Laird M +7 more
europepmc +1 more source
Boron neutron capture therapy (BNCT) for head and neck tumor
ホウ素中性子捕捉療法(Boron neutron capture therapy, 以下BNCT)は,主として悪性脳腫瘍,悪性黒色腫に対して施行されてきた。2001年に標準治療後の再発耳下腺癌に対して,BNCTが世界初の試みとして実施され,放射線治療後の再照射であったにもかかわらず,重篤な有害事象を引き起こさずに腫瘍が著しく縮小した。それ以来,頭頸部腫瘍に対するBNCTの施行例は増加しており,日本とフィンランドから,頭頸部腫瘍に対するBNCTの治療効果として,重篤な有害事象は認めず,良好な局所治療効果が得られているとの報告がされている。今後,BNCTが頭頸部腫瘍の臨床現場に対して大きな貢献をするためには,原子炉を中性子源とするBNCTでは,症例数の限界がある。その現状を打破するため ...
openaire +1 more source
Diastereoselective Synthesis of the Borylated d-Galactose Monosaccharide 3-Boronic-3-Deoxy-d-Galactose and Biological Evaluation in Glycosidase Inhibition and in Cancer for Boron Neutron Capture Therapy (BNCT). [PDF]
Simone MI.
europepmc +1 more source
Cobaltabis(dicarbollide) ([o-COSAN]-) as Multifunctional Chemotherapeutics: A Prospective Application in Boron Neutron Capture Therapy (BNCT) for Glioblastoma. [PDF]
Nuez-Martinez M +12 more
europepmc +1 more source
Boron neutron capture therapy (BNCT) is a radiotherapy treatment based on the accumulation in the tumor of a 10B-containing drug and subsequent irradiation with low energy neutrons, which bring about the decay of 10B to 7Li and an particle, causing the ...
ACHILLI, CESARE +14 more
core +1 more source
Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry Imaging of L-4-Phenylalanineboronic Acid (BPA) in a Brain Tumor Model Rat for Boron Neutron Capture Therapy (BNCT). [PDF]
Miyake Y, Kusaka S, Murata I, Toyoda M.
europepmc +1 more source
Nanocarriers have been researched comprehensively for the development of novel boron-containing agents in boron neutron capture therapy (BNCT). We designed and synthesized a multifunctional mesoporous silica nanoparticle (MSN)-based boron-containing ...
Fan Hu (277859) +23 more
core +1 more source
Response of Normal Tissues to Boron Neutron Capture Therapy (BNCT) with 10B-Borocaptate Sodium (BSH) and 10B-Paraboronophenylalanine (BPA). [PDF]
Fukuda H.
europepmc +1 more source
Abstrak – Cancer is a dangerous disease which is one of the main causes of death in the world, which is 8.8 million deaths in 2015. A new method has been developed for the treatment of cancer with small side effects, Boron Neutron Capture Therapy (BNCT).
Laura Laudensia Senly Jalut +2 more
doaj
Evaluation of local, regional and abscopal effects of Boron Neutron Capture Therapy (BNCT) combined with immunotherapy in an ectopic colon cancer model. [PDF]
Trivillin VA +15 more
europepmc +1 more source

