Results 1 to 10 of about 8,497 (207)

Clinical outcomes of boron neutron capture therapy for unresectable oral cancer: a retrospective analysis [PDF]

Frontiers in Oncology
BackgroundSurgery is the standard treatment for oral cancer but often causes functional and cosmetic problems, and reoperation is difficult. Radiotherapy (RT) is less effective, with reirradiation limited by normal tissue tolerance and salvage surgery ...
Yuki Yoshino, Yuki Yoshino, Yuki Yoshino, Satoshi Takeno, Satoshi Takeno, Teruhito Aihara, Teruhito Aihara, Naonori Hu, Naonori Hu, Akinori Sasaki, Kazuhiko Akita, Yasukazu Kanai, Yasukazu Kanai, Mai Nojiri, Tsuyoshi Jinnin, Tetsuya Terada, Shinichi Haginomori, Keiji Nihei, Keiji Nihei, Koji Ono, Koji Ono   +20 more
doaj   +2 more sources

Next-Generation Boron Drugs and Rational Translational Studies Driving the Revival of BNCT

Cells, 2023
BNCT is a high-linear-energy transfer therapy that facilitates tumor-directed radiation delivery while largely sparing adjacent normal tissues through the biological targeting of boron compounds to tumor cells.
danushka seneviratne, Yuri A Mackeyev, Sunil Krishnan   +2 more
exaly   +3 more sources

Accelerator-based BNCT [PDF]

Applied Radiation and Isotopes, 2014
The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented.
Kreiner, Andres Juan, Baldo, Monica Iris, Bergueiro, Rodolfo Javier, Cartelli, Daniel Enrique, Castell, W., Thatar Vento, Vladimir, Gomez Asoia, J., Mercuri, D., Padulo, J., Suarez Sandin, J. C., Erhardt, J., Kesque, J. M., Valda, A. A., Debray, Mario Ernesto, Somacal, Héctor Rubén, Igarzabal, M., Minsky, Daniel Mauricio, Herrera, Maria Silvia, Capoulat, Maria Eugenia, González, Sara Josefina, del Grosso, Mariela Fernanda, Gagetti, Leonardo, Suárez Anzorena; M., Gun, M., Carranza, O.   +24 more
exaly   +4 more sources

Clinical Veterinary Boron Neutron Capture Therapy (BNCT) Studies in Dogs with Head and Neck Cancer: Bridging the Gap between Translational and Clinical Studies

Biology, 2020
Translational Boron Neutron Capture Therapy (BNCT) studies performed by our group and clinical BNCT studies worldwide have shown the therapeutic efficacy of BNCT for head and neck cancer. The present BNCT studies in veterinary patients with head and neck
Amanda Elena Schwint, Andrea Monti Hughes, Marcela Alejandra Garabalino   +2 more
exaly   +3 more sources

Advances in Clinical Trials of Boron Neutron Capture Therapy [PDF]

Research
Boron neutron capture therapy (BNCT) is a targeted radiotherapy technique that enables dual targeting at the physico-biological level. Efficient neutron sources and specific boron carriers are essential for successful treatment. By exploiting the 10B(n,α)
Xiaoling Li, Zhijie Liu, Kejun Liu, Chunhong Wang, Zhigang Liu, Xiao Xu   +5 more
doaj   +2 more sources

Present status of Accelerator-Based BNCT [PDF]

Reports of Practical Oncology and Radiotherapy, 2016
This work aims at giving an updated report of the worldwide status of Accelerator-Based BNCT (AB-BNCT).There is a generalized perception that the availability of accelerators installed in hospitals, as neutron sources, may be crucial for the advancement of BNCT.
Kreiner, Andres Juan, Bergueiro, Rodolfo Javier, Cartelli, Daniel Enrique, Baldo, Matias Nicolas, Castello, Walter Braulio, Asoia, Javier Gomez, Padulo, Javier, Suárez Sandín, Juan Carlos, Igarzabal, Marcelo, Erhardt, Julian, Mercuri, Daniel, Valda, Alejandro A., Minsky, Daniel Mauricio, Debray, Mario Ernesto, Somacal, Héctor Rubén, Capoulat, Maria Eugenia, Herrera, Maria Silvia, del Grosso, Mariela Fernanda, Gagetti, Leonardo, Suarez Anzorena, Manuel, Canepa, Nicolas, Real, Nicolas, Gun, Marcelo, Tacca, Hernán Emilio   +23 more
exaly   +4 more sources

Boron neutron capture therapy preserves immune cells and induces robust anti-tumour immunity in preclinical mouse model [PDF]

Nature Communications
Radiotherapy can both activate and suppress immunity, making it difficult to predict or modulate these opposing effects for better cancer treatment.
Qi Sun, Yanping Zhao, Simiao Qiao, Kexuan Wang, Chuanjie Lu, Zizhu Zhang, Zhibin Guo, Zexuan Ding, Chunhong Wang, Jiyuan Li, Tong Liu, Zexian Zeng, Zhibo Liu   +12 more
doaj   +2 more sources

Boron neutron capture therapy for melanoma: recent advances and future prospects [PDF]

Frontiers in Oncology
Boron neutron capture therapy (BNCT) is a unique radiotherapy modality that targets and destroys selectively tumor cells that have absorbed boron, while leaving surrounding healthy cells unharmed.
Yuanyang Sun, Yun Wang, Shukun Mu, Xiaofeng Wu, Suchun Yu, Zhongming Wang   +5 more
doaj   +2 more sources

Mechanotransduction-related ferroptosis: Enhancing boron neutron capture therapy efficacy in glioblastoma using a spheroid model [PDF]

Molecular Therapy: Oncology
Boron neutron capture therapy (BNCT) shows potential for the treatment of glioblastoma, the most aggressive form of primary brain tumor. Recently, ferroptosis, a cell death triggered by phospholipid peroxidation, has been identified as an important ...
Lin-Sheng Yu, Jia-Jun Liu, Ming-Hung Yang, Yu-chun Lin, Chi-Shuo Chen   +4 more
doaj   +2 more sources

Development and evaluation of surface-guided patient position system for boron neutron capture therapy [PDF]

Scientific Reports
Boron Neutron Capture Therapy (BNCT) is an advanced form of radiotherapy that uses the neutron capture reaction of boron-10 to selectively destroy cancer cells.
Jiang Chen, Qiao-Lin Xie, Jing-Jing Ping, Ting-Ting Hou, Yuan-Hao Liu   +4 more
doaj   +2 more sources