Results 31 to 40 of about 6,494 (198)
Application and Development of Tumor-Targeting Boron Carriers in Boron Neutron Capture Therapy
He huaxue yu fangshe huaxue, 2023 Boron neutron capture therapy(BNCT) is a promising therapeutic method for malignant tumors and has entered the clinical trials. As a binary cellular accurate therapy, BNCT relies on tumor-targeting boron delivery.
CHEN Kui, LYU Lin-wen, XING Geng-mei
doaj +1 more source
Scientific Reports, 2023 Boron neutron capture therapy (BNCT) is a high-LET particle radiotherapy clinically tested for treating malignant gliomas. Boronophenylalanine (BPA), a boron-containing phenylalanine derivative, is selectively transported into tumor cells by amino acid ...
Masao Fukumura +15 more
doaj +1 more source
Carborane Polypeptide Derivatives for Boron Neutron Capture Therapy
He huaxue yu fangshe huaxue, 2023 The design and application of carborane polypeptide derivatives have attracted more and more attention, especially as boron carrier in the treatment of malignant tumors(BNCT).
HAN Yi, LI Feng-lin, LUO Zhi-fu
doaj +1 more source
“Sequential” Boron Neutron Capture Therapy (BNCT): A Novel Approach to BNCT for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model [PDF]
, 2011 In the present study the therapeutic effect and potential toxicity of the novel "“Sequential"†boron neutron capture therapy (Seq-BNCT) for the treatment of oral cancer was evaluated in the hamster cheek pouch model at the RA-3 Nuclear Reactor.
Itoiz, María Elina +27 more
core +1 more source
PLoS ONE, 2019 Nine patients with recurrent head and neck (H&N) cancer received boron neutron capture therapy (BNCT) in one fraction at the Tsing-Hua Open pool reactor (THOR) utilizing the THORplan treatment planning system (TPS).
Jia-Cheng Lee +5 more
doaj +1 more source
Current development status of accelerator-based neutron source for boron neutron capture therapy
EPJ Techniques and Instrumentation, 2023 Recently, progress in technology for accelerator-based neutron sources has increased attention regarding boron neutron capture therapy (BNCT). BNCT is a type of radiotherapy that combines neutrons and boron drugs and is expected to be used in the ...
Hiroaki Kumada +2 more
doaj +1 more source
Journal of Physics: Conference Series, 2006 The experience from physical field for the BNCT project realized in NRI (Czech Republic) is presented. The physical methods and equipments for the design, construction and operation of facility for medical application are summarized. The comment is concentrated to the following items, especially: Sources for BNCT, calculation methods, measurement ...
J Burian +5 more
openaire +1 more source
FriXy gel dosimeters for fast neutron dose in BNCT epithermal beams
, 2007 BNCT thermal neutron beams, for their low penetration power, are useful only for shallow depth tumour treatments; the therapeutic benefits of neutron beams can be extended to deeper tissues (until depths of several centimeters) increasing their energy ...
G. BARTESAGHI
core +2 more sources
The Anti-Proliferative Effect of Boron Neutron Capture Therapy in a Prostate Cancer Xenograft Model. [PDF]
PLoS ONE, 2015 Boron neutron capture therapy (BNCT) is a selective radiation treatment for tumors that preferentially accumulate drugs carrying the stable boron isotope, 10B. BNCT has been evaluated clinically as an alternative to conventional radiation therapy for the
Kiyoshi Takahara +14 more
doaj +1 more source
Advances of LINAC-based boron neutron capture therapy in Korea
AAPPS Bulletin, 2022 Boron neutron capture therapy (BNCT) has been attracting interest as a new radiation modality for cancer therapy because it can selectively destroy cancer cells while maintaining the healthy state of surrounding normal cells.
Young-soon Bae +47 more
doaj +1 more source