Results 31 to 40 of about 2,179 (173)

Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors

open access: yesВестник рентгенологии и радиологии, 2016
Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers.
V. V. Kanygin   +3 more
doaj   +1 more source

Current development status of accelerator-based neutron source for boron neutron capture therapy

open access: yesEPJ Techniques and Instrumentation, 2023
Recently, progress in technology for accelerator-based neutron sources has increased attention regarding boron neutron capture therapy (BNCT). BNCT is a type of radiotherapy that combines neutrons and boron drugs and is expected to be used in the ...
Hiroaki Kumada   +2 more
doaj   +1 more source

A comparison of dose distributions in gross tumor volume between boron neutron capture therapy alone and combined boron neutron capture therapy plus intensity modulation radiation therapy for head and neck cancer.

open access: yesPLoS ONE, 2019
Nine patients with recurrent head and neck (H&N) cancer received boron neutron capture therapy (BNCT) in one fraction at the Tsing-Hua Open pool reactor (THOR) utilizing the THORplan treatment planning system (TPS).
Jia-Cheng Lee   +5 more
doaj   +1 more source

An Introduction to Boron Neutron Therapy (BNCT): Current Status and Future Outlook

open access: yesIranian South Medical Journal, 2021
Boron neutron capture therapy (BNCT) is based on the nuclear reaction, such that B-10 irradiated with low-energy thermal neutrons produces alpha particles with high linear energy transfer and lithium-7. Clinically, BNCT is used primarily for treatment of
Malehe Omrani   +3 more
doaj  

The Anti-Proliferative Effect of Boron Neutron Capture Therapy in a Prostate Cancer Xenograft Model. [PDF]

open access: yesPLoS ONE, 2015
Boron neutron capture therapy (BNCT) is a selective radiation treatment for tumors that preferentially accumulate drugs carrying the stable boron isotope, 10B. BNCT has been evaluated clinically as an alternative to conventional radiation therapy for the
Kiyoshi Takahara   +14 more
doaj   +1 more source

Salvage Boron Neutron Capture Therapy for Malignant Brain Tumor Patients in Compliance with Emergency and Compassionate Use: Evaluation of 34 Cases in Taiwan

open access: yesBiology, 2021
Although boron neutron capture therapy (BNCT) is a promising treatment option for malignant brain tumors, the optimal BNCT parameters for patients with immediately life-threatening, end-stage brain tumors remain unclear.
Yi-Wei Chen   +34 more
doaj   +1 more source

Advances of LINAC-based boron neutron capture therapy in Korea

open access: yesAAPPS Bulletin, 2022
Boron neutron capture therapy (BNCT) has been attracting interest as a new radiation modality for cancer therapy because it can selectively destroy cancer cells while maintaining the healthy state of surrounding normal cells.
Young-soon Bae   +47 more
doaj   +1 more source

Chitosan-lactobionic acid-thioctic acid-modified hollow mesoporous silica composite loaded with carborane for boron neutron capture therapy of hepatocellular carcinoma

open access: yesMaterials & Design, 2022
Nanocarriers have been recognized as an effective strategy for developing novel boron-containing delivery agents for boron neutron capture therapy (BNCT) of refractory tumors.
Taofeng Zhang   +13 more
doaj   +1 more source

Synthesis and Functional Properties of Fluorinated Phosphonate‐Substituted Porphyrins: Excellent Photosensitizers and Robust Precursors for Photoactive Langmuir–Schaefer Films

open access: yesChemistry – A European Journal, EarlyView.
This is a comprehensive study of new family of high functionalized meso‐tetraarylporphyrins. A synthetic approach to phosphonate‐substituted fluorinated porphyrins was developed. These compounds were investigated with respect to singlet oxygen generation and photostability.
Azhar Kechiche   +8 more
wiley   +1 more source

Extracellular Release of HMGB1 as an Early Potential Biomarker for the Therapeutic Response in a Xenograft Model of Boron Neutron Capture Therapy

open access: yesBiology, 2022
Boron neutron capture therapy (BNCT) is a non-invasive therapeutic technique for treating malignant tumors, however, methods to evaluate its therapeutic efficacy and adverse reactions are lacking.
Shoji Imamichi   +14 more
doaj   +1 more source

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