Results 1 to 10 of about 5,770 (216)

Theranostics in Boron Neutron Capture Therapy [PDF]

Life, 2021
Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied ...
Wolfgang A. G. Sauerwein, Lucie Sancey, Evamarie Hey-Hawkins, Martin Kellert, Luigi Panza, Daniela Imperio, Marcin Balcerzyk, Giovanna Rizzo, Elisa Scalco, Ken Herrmann, PierLuigi Mauri, Antonella De Palma, Andrea Wittig   +12 more
doaj   +8 more sources

Boron Neutron Capture Therapy - A Literature Review [PDF]

Journal of Clinical and Diagnostic Research, 2016
Boron Neutron Capture Therapy (BNCT) is a radiation science which is emerging as a hopeful tool in treating cancer, by selectively concentrating boron compounds in tumour cells and then subjecting the tumour cells to epithermal neutron beam radiation ...
Kavitaa Nedunchezhian, Nalini Aswath, Manigandan Thiruppathy, Sarumathi Thirugnanamurthy   +3 more
doaj   +3 more sources

Boron‐10 carriers and their applications in boron neutron capture therapy [PDF]

Precis Radiat Oncol
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Tang D, Shi M, Mao Z, Chen W, Li X, Zhao X, Liu Z, Xu X.   +7 more
europepmc   +2 more sources

Potential targets for boron transport in boron neutron capture therapy [PDF]

Frontiers in Oncology
Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy that involves boron (10B) drug administration and epithermal/thermal neutron irradiation. The nuclear fission reaction between low-energy thermal neutrons and 10B atoms accumulated in cancer
Yucai Wei, Yucai Wei, Yucai Wei, Weijing Zhu, Weijing Zhu, Qian Chen, Huda Alnufaei, Yumin Li, Yumin Li, Kate Ricketts   +9 more
doaj   +2 more sources

Emerging agents for boron neutron capture therapy: Biomolecular carriers paving the way for precision radiotherapy [PDF]

Precis Radiat Oncol
Boron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chen C, Yang M, Wang J, Zhang L, Huang S, Xu X, Liu Y.   +6 more
europepmc   +2 more sources

Systemic Immunity Triggered by Boron Neutron Capture Therapy via Manganese-Borate Complex [PDF]

Materials Today Bio
Conventional radiotherapy compromises antitumor immunity through collateral damage to immune cells. While boron neutron capture therapy (BNCT) enables tumor-selective 10B (n, α) 7Li reactions, clinical agents like boronophenylalanine (BPA) suffer from ...
Chang Chen, Chao Wang, Lin Zhang, Yue Yu, Xu Li, Wenhao Pan, Yuanyu Liu, Jiheng Wang, Maosong Yang, Bing Hong, Xingguang Hu, Jichao Wang, Yuzhong Qian, Xiancai Meng, Yinghuai Zhu, Zhigang Liu, Shaobo Huang, Lizheng Liang, Jinhui Wu, Yang Liu   +19 more
doaj   +2 more sources

Clinical application of boron neutron capture therapy for cancer treatment: A systematic review [PDF]

Precision Radiation Oncology
Boron neutron capture therapy (BNCT) combines boron drug delivery and heavy‐ion therapy. The key factors in the application of BNCT are high‐quality neutron beams and boron‐containing compounds.
Ling Zhou, Yuming Chen, Meng Peng, Xiumao Yin, Huanqing Liang, Jieming Mo, Wan Zhang, Zhigang Liu   +7 more
doaj   +2 more sources

Boron neutron capture therapy for malignant gliomas

Annals of Medicine, 2000
Boron neutron capture therapy (BNCT) represents a promising modality for a relatively selective radiation dose delivery to the tumour tissue. Boron-10 nuclei capture slow 'thermal' neutrons preferentially and, upon capture, promptly undergo 10B(n,alpha)7Li reaction.
Aidnag Z Diaz, Jeffrey A Coderre, A D Chanana   +2 more
exaly   +3 more sources

Investigation of photon doses reaching healthy tissues in the use of different neutron energies in boron neutron capture therapy [PDF]

Nuclear Technology and Radiation Protection, 2022
Boron neutron capture therapy is a unique treatment method that aims to kill the tumor cells with the help of heavy particles. Particles resulting from the interaction of the tumor region containing 10B atoms with thermal or epithermal neutrons ...
Tugrul Taylan
doaj   +1 more source

Construction of targeted 10B delivery agents and their uptake in gastric and pancreatic cancer cells

Frontiers in Oncology, 2023
Boron Neutron Capture Therapy (BNCT) is a new binary radiation therapy for tumor tissue, which kills tumor cells with neutron capture reaction. Boron neutron capture therapy has become a technical means for glioma, melanoma, and other diseases has been ...
Song Wang, Song Wang, Zhengchao Zhang, Zhengchao Zhang, Lele Miao, Lele Miao, Jiaxing Zhang, Jiaxing Zhang, Futian Tang, Futian Tang, Muzhou Teng, Muzhou Teng, Yumin Li, Yumin Li   +13 more
doaj   +1 more source