Results 21 to 30 of about 5,770 (216)

Experimental study on Compton camera for boron neutron capture therapy applications

open access: yesScientific Reports, 2023
Boron neutron capture therapy (BNCT) is a high-dose-intensive radiation therapy that has gained popularity due to advancements in accelerator neutron sources.
M. Sakai   +6 more
doaj   +1 more source

Boron Neutron Capture Therapy: Microdosimetry at Different Boron Concentrations

open access: yesApplied Sciences, 2023
This paper explores the role of microdosimetry in boron neutron capture therapy (BNCT), a cancer treatment involving the selective accumulation of boron-containing compounds in cancer cells, followed by neutron irradiation.
Valeria Conte, Anna Bianchi, Anna Selva
doaj   +1 more source

Nanostructured boron agents for boron neutron capture therapy: a review of recent patents

open access: yesMedical Review, 2023
Boron neutron capture therapy (BNCT) is a potential radiation therapy modality for cancer, and tumor-targeted stable boron-10 (10B) delivery agents are an important component of BNCT. Currently, two low-molecular-weight boron-containing compounds, sodium
Zhang Xiyin   +3 more
doaj   +1 more source

Monte Carlo simulation of tilted contact plaque brachytherapy placement for juxtapapillary retinoblastoma

open access: yesRadiation Oncology, 2022
Background The 106-Ruthenium contact plaque applicator is utilized for the treatment of intraocular tumor within a thickness of less than 6 mm. If anything obstructs the placement of the plaque applicator, the treatment is generally difficult because the
Satoshi Nakamura   +13 more
doaj   +1 more source

Boron neutron capture therapy for urological cancers [PDF]

open access: yesInternational Journal of Urology, 2022
AbstractBoron neutron capture therapy is based on a nuclear reaction between the nonradioactive isotope boron‐10 and either low‐energy thermal neutrons or high‐energy epithermal neutrons, which generate high linear energy transfer α particles and a recoiled lithium nucleus (7Li) that selectively destroys the DNA helix in tumor cells.
Kiyoshi Takahara   +3 more
openaire   +2 more sources

Development and Elucidation of a Novel Fluorescent Boron-Sensor for the Analysis of Boronic Acid-Containing Compounds

open access: yesSensors, 2017
Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods.
Yoshihide Hattori   +4 more
doaj   +1 more source

Boron encapsulated in a liposome can be used for combinational neutron capture therapy

open access: yesNature Communications, 2022
Boron neutron capture therapy is a type of cancer therapy but is associated with insufficient boron delivery and with poor biocompatibility. Here, the authors constructed boronated lipids to generate - boronsome - and show the system can reduce tumour ...
Jiyuan Li   +8 more
doaj   +1 more source

The basis and advances in clinical application of boron neutron capture therapy

open access: yesRadiation Oncology, 2021
Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He   +9 more
doaj   +1 more source

A Review of Boron Neutron Capture Therapy: Its History and Current Challenges

open access: yes, 2022
MECHANISM OF ACTION: External beam, whether with photons or particles, remains as the most common type of radiation therapy. The main drawback is that radiation deposits dose in healthy tissue before reaching its target.
Seldon, Crystal   +4 more
core   +1 more source

BeNEdiCTE (Boron NEutron CapTurE): a Versatile Gamma-Ray Detection Module for Boron Neutron Capture Therapy

open access: yes, 2022
We present a gamma-ray detection module for quantifying the boron neutron capture events that occur in Boron Neutron Capture Therapy (BNCT) and Neutron Capture Enhanced Particle Therapy (NCEPT).
Safavi-Naeini, Mitra   +8 more
core   +2 more sources

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