Results 21 to 30 of about 14,053 (266)

MRI and ¹⁸F-BPA PET-guided targeting in boron neutron capture therapy. [PDF]

Sci Rep
Hu CR, Lai YQ, Cao Y, Pan JJ, Liu YH, Teng YC, Xia XB.   +6 more
europepmc   +3 more sources

Boron encapsulated in a liposome can be used for combinational neutron capture therapy

Nature Communications, 2022
Boron neutron capture therapy is a type of cancer therapy but is associated with insufficient boron delivery and with poor biocompatibility. Here, the authors constructed boronated lipids to generate - boronsome - and show the system can reduce tumour ...
Jiyuan Li, Qi Sun, Chuanjie Lu, Han Xiao, Zhibin Guo, Dongban Duan, Zizhu Zhang, Tong Liu, Zhibo Liu   +8 more
doaj   +1 more source

Radiobiological response of U251MG, CHO-K1 and V79 cell lines to accelerator-based boron neutron capture therapy [PDF]

, 2017
In the current article, we provide in vitro efficacy evaluation of a unique accelerator-based neutron source, constructed at the Budker Institute of Nuclear Physics (Novosibirsk, Russian Federation), for boron neutron capture therapy (BNCT), which is ...
Isobe Tomonori, Kanygin Vladimir, Mathis Bryan J, Matsumura Akira, Mechetina Ludmila, Nakai Kei, Sato Eisuke, Taranin Alexander, Taskaev Sergey, Volkova Olga, Yamamoto Tetsuya, Zaboronok Alexander, ザボロノク アレクサンドル, マティス ブライアン　 ジェームズ, 松村 明, 磯辺 智範   +15 more
core   +2 more sources

The basis and advances in clinical application of boron neutron capture therapy

Radiation Oncology, 2021
Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He, Jiyuan Li, Ping Jiang, Suqing Tian, Hao Wang, Ruitai Fan, Junqi Liu, Yuyan Yang, Zhibo Liu, Junjie Wang   +9 more
doaj   +1 more source

Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment

Cells, 2022
Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission process that occurs upon thermal neutron irradiation of 10B-containing compounds; this process causes the release of alpha particles that selectively damage ...
Giorgia Ailuno, Alice Balboni, Gabriele Caviglioli, Francesco Lai, Federica Barbieri, Irene Dellacasagrande, Tullio Florio, Sara Baldassari   +7 more
doaj   +1 more source

Site‐Selective B─H Activation via HAT Toward Xanthyl‐closo‐Carboranes as Bench‐Stable Precursors of Organosulfur Boron Clusters

Angewandte Chemie, EarlyView.
A light mediated direct regioselective B─H functionalization, via hydrogen atom transfer (HAT), is described. Unexplored xanthyl‐closo‐carboranes as novel bench‐stable and versatile platforms to access sulfur‐containing boron clusters are reported for the first time.
Marco Rusconi, Eugenia Magi, Polyssena Renzi, Emanuele Azzi, Valeria Lagostina, Enrico Salvadori, Mario Chiesa, Birgit Hischa, Giovanni Ghigo, Annamaria Deagostino   +9 more
wiley   +2 more sources

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine

Biology, 2021
Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment exploiting a nuclear reaction occurring in tumor cells [...]
Silva Bortolussi, Yuan-Hao Liu, Ignacio Porras   +2 more
doaj   +1 more source

The Birmingham Boron Neutron Capture Therapy (BNCT) project : developments towards selective internal particle therapy [PDF]

, 2011
This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compound ...
Boddy, A., Charles, M. W., Croswell, G., Cruickshank, G. S., Detta, A., Doran, J., Elliott, M., Ford, S., Ghani, Z., Graham, N., Green, S., Halbert, G., Hill, M., James, N. D., Jones, B., King, A., Lockyer, N., Mill, A. J., Ngoga, D., Phoenix, B., Sheehan, T. M. T., Thompson, J., Vickerman, J., Wojnecki, C.   +23 more
core   +1 more source

Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA

Frontiers in Nuclear Engineering, 2023
The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s ...
Marina Bikchurina, Timofey Bykov, Ibrahim Ibrahim, Ibrahim Ibrahim, Ibrahim Ibrahim, Anna Kasatova, Dmitrii Kasatov, Iaroslav Kolesnikov, Victoria Konovalova, Victoria Konovalova, Timur Kormushakov, Timur Kormushakov, Alexey Koshkarev, Alexey Koshkarev, Anton Kuznetsov, Anton Kuznetsov, Vyacheslav Porosev, Sergey Savinov, Ivan Shchudlo, Nataliia Singatulina, Nataliia Singatulina, Evgeniia Sokolova, Tatiana Sycheva, Iuliia Taskaeva, Gleb Verkhovod, Sergey Taskaev, Sergey Taskaev   +26 more
doaj   +1 more source

Boron distribution in the normal rat brain after intravenous injection of boronophenylalanine-fructose [PDF]

, 2008
Boron neutron capture therapy (BNCT) is an experimental form of radiation therapy for malignant brain tumors and peripheral melanoma. The micro-distribution of the boron compound is critical to determine the radiation effects for both tumors and normal ...
Shibata Yasushi, 柴田 靖
core   +1 more source