Results 31 to 40 of about 3,756,603 (159)

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT)

Pharmaceutics, 2023
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT).
Juulia Järvinen, Herkko Pulkkinen, Jarkko Rautio, Juri M. Timonen   +3 more
doaj   +1 more source

A Review of Boron Neutron Capture Therapy: Its History and Current Challenges

, 2022
MECHANISM OF ACTION: External beam, whether with photons or particles, remains as the most common type of radiation therapy. The main drawback is that radiation deposits dose in healthy tissue before reaching its target.
Seldon, Crystal, Butkus, Michael, Sauerwein, Wolfgang, Giap, Huan B., Jin, Will H.   +4 more
core   +1 more source

Potential of a compact low energy proton accelertor for medical applications [PDF]

This thesis explores the potential of a compact low energy (
Ratcliffe, Naomi
core   +3 more sources

Feasibility of Prompt Gamma-Ray Imaging in BNCT: SPECT-Based MCNP Simulations of Boron and Hydrogen Capture Events [PDF]

Journal of Radiation Protection and Research
Background Boron neutron capture therapy (BNCT) is a targeted radiotherapy that selectively destroys cancer cells by delivering compounds enriched in boron-10 (10B) that preferentially accumulate in tumors.
Milad Mohammedali, Wonho Lee
doaj   +1 more source

Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA

Frontiers in Nuclear Engineering, 2023
The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s ...
Marina Bikchurina, Timofey Bykov, Ibrahim Ibrahim, Ibrahim Ibrahim, Ibrahim Ibrahim, Anna Kasatova, Dmitrii Kasatov, Iaroslav Kolesnikov, Victoria Konovalova, Victoria Konovalova, Timur Kormushakov, Timur Kormushakov, Alexey Koshkarev, Alexey Koshkarev, Anton Kuznetsov, Anton Kuznetsov, Vyacheslav Porosev, Sergey Savinov, Ivan Shchudlo, Nataliia Singatulina, Nataliia Singatulina, Evgeniia Sokolova, Tatiana Sycheva, Iuliia Taskaeva, Gleb Verkhovod, Sergey Taskaev, Sergey Taskaev   +26 more
doaj   +1 more source

Assesment of Boron Neutron Capture Therapy (BNCT): Compact Neutron Generators [PDF]

, 2018
Boron  Neutron Capture Therapy (BNCT)  is an effective and promising treatment          of tumour types which are resistant to conventional therapies.
Sardjono, Yohannes, Wahyuni, Nur Setyo
core   +1 more source

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Journal of Pharmacological Sciences, 2019
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by ...
Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai   +12 more
doaj   +1 more source

Targeted delivery of advanced functionality by nanomaterials : focus on nucleic acids delivery by novel block copolymers [PDF]

, 2014
: Smart drug delivery systems are versatile examples of successful nanomedicine with potential in diagnostics and medical therapy. The thesis presents selected approaches in current drug delivery systems in the (pre-)clinical trials, and deals with ...
Lehner, Roman
core   +1 more source

PK Modeling of L-4-Boronophenylalanine and Development of Bayesian Predictive Platform for L-4-Boronophenylalanine PKs for Boron Neutron Capture Therapy

Pharmaceuticals
L-4-[(10B)]Boronophenylalanine (BPA) is an amino acid analogue with a boron-10 moiety. It is most widely used as a boron carrier in boron neutron capture therapy.
Woohyoung Kim, Ji Yeong Won, Jungyu Yi, Seung Chan Choi, Sang Min Lee, Kyungran Mun, Hyeong-Seok Lim   +6 more
doaj   +1 more source

7. Neutron Capture Therapy [PDF]

, 2023
In case that corrections are made, overwrite the modified version in the following web page: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2022/ProgRep2022.htmlCO7-1 Development of Alubmin Binding Gadolinium Complexes for MRI-Guided BNCT/ S.

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