Results 11 to 20 of about 14,053 (266)

Theranostics in Boron Neutron Capture Therapy [PDF]

open access: yesLife, 2021
Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied ...
Wolfgang A. G. Sauerwein   +12 more
doaj   +6 more sources

Boron Neutron Capture Therapy - A Literature Review [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Boron Neutron Capture Therapy (BNCT) is a radiation science which is emerging as a hopeful tool in treating cancer, by selectively concentrating boron compounds in tumour cells and then subjecting the tumour cells to epithermal neutron beam radiation ...
Kavitaa Nedunchezhian   +3 more
doaj   +3 more sources

In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

open access: yesScientific Reports, 2022
While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly relies on gamma rays and Auger electrons ...
Woonghee Lee   +6 more
doaj   +1 more source

Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy

open access: yesMolecules, 2021
Boron neutron capture therapy is a unique form of adjuvant cancer therapy for various malignancies including malignant gliomas. The conjugation of boron compounds and human serum albumin (HSA)—a carrier protein with a long plasma half-life—is expected to
Tatyana Popova   +9 more
doaj   +1 more source

Correlation between L‐amino acid transporter 1 expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine accumulation in humans

open access: yesCancer Medicine, 2023
Background The correlation between L‐type amino acid transporter 1 (LAT1) expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine (18F‐FBPA) accumulation in humans remains unclear.
Tairo Kashihara   +9 more
doaj   +1 more source

Boron Neutron Capture Therapy: Microdosimetry at Different Boron Concentrations

open access: yesApplied Sciences, 2023
This paper explores the role of microdosimetry in boron neutron capture therapy (BNCT), a cancer treatment involving the selective accumulation of boron-containing compounds in cancer cells, followed by neutron irradiation.
Valeria Conte, Anna Bianchi, Anna Selva
doaj   +1 more source

Nanostructured boron agents for boron neutron capture therapy: a review of recent patents

open access: yesMedical Review, 2023
Boron neutron capture therapy (BNCT) is a potential radiation therapy modality for cancer, and tumor-targeted stable boron-10 (10B) delivery agents are an important component of BNCT. Currently, two low-molecular-weight boron-containing compounds, sodium
Zhang Xiyin   +3 more
doaj   +1 more source

Boron neutron capture therapy for urological cancers [PDF]

open access: yesInternational Journal of Urology, 2022
AbstractBoron neutron capture therapy is based on a nuclear reaction between the nonradioactive isotope boron‐10 and either low‐energy thermal neutrons or high‐energy epithermal neutrons, which generate high linear energy transfer α particles and a recoiled lithium nucleus (7Li) that selectively destroys the DNA helix in tumor cells.
Kiyoshi Takahara   +3 more
openaire   +2 more sources

Monte Carlo simulation of tilted contact plaque brachytherapy placement for juxtapapillary retinoblastoma

open access: yesRadiation Oncology, 2022
Background The 106-Ruthenium contact plaque applicator is utilized for the treatment of intraocular tumor within a thickness of less than 6 mm. If anything obstructs the placement of the plaque applicator, the treatment is generally difficult because the
Satoshi Nakamura   +13 more
doaj   +1 more source

Development and Elucidation of a Novel Fluorescent Boron-Sensor for the Analysis of Boronic Acid-Containing Compounds

open access: yesSensors, 2017
Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods.
Yoshihide Hattori   +4 more
doaj   +1 more source

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