Results 11 to 20 of about 588 (131)
Molecules, 2021 Boron neutron capture therapy is a unique form of adjuvant cancer therapy for various malignancies including malignant gliomas. The conjugation of boron compounds and human serum albumin (HSA)—a carrier protein with a long plasma half-life—is expected to
Tatyana Popova +9 more
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Cancer Medicine, 2023 Background The correlation between L‐type amino acid transporter 1 (LAT1) expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine (18F‐FBPA) accumulation in humans remains unclear.
Tairo Kashihara +9 more
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Experimental study on Compton camera for boron neutron capture therapy applications
Scientific Reports, 2023 Boron neutron capture therapy (BNCT) is a high-dose-intensive radiation therapy that has gained popularity due to advancements in accelerator neutron sources.
M. Sakai +6 more
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Nanostructured boron agents for boron neutron capture therapy: a review of recent patents
Medical Review, 2023 Boron neutron capture therapy (BNCT) is a potential radiation therapy modality for cancer, and tumor-targeted stable boron-10 (10B) delivery agents are an important component of BNCT. Currently, two low-molecular-weight boron-containing compounds, sodium
Zhang Xiyin +3 more
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Boron Neutron Capture Therapy: Microdosimetry at Different Boron Concentrations
Applied Sciences, 2023 This paper explores the role of microdosimetry in boron neutron capture therapy (BNCT), a cancer treatment involving the selective accumulation of boron-containing compounds in cancer cells, followed by neutron irradiation.
Valeria Conte, Anna Bianchi, Anna Selva
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Radiation Oncology, 2022 Background The 106-Ruthenium contact plaque applicator is utilized for the treatment of intraocular tumor within a thickness of less than 6 mm. If anything obstructs the placement of the plaque applicator, the treatment is generally difficult because the
Satoshi Nakamura +13 more
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Sensors, 2017 Novel boron-containing drugs have recently been suggested as a new class of pharmaceuticals. However, the majority of current boron-detection techniques require expensive facilities and/or tedious pretreatment methods.
Yoshihide Hattori +4 more
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Boron neutron capture therapy for urological cancers [PDF]
International Journal of Urology, 2022 AbstractBoron neutron capture therapy is based on a nuclear reaction between the nonradioactive isotope boron‐10 and either low‐energy thermal neutrons or high‐energy epithermal neutrons, which generate high linear energy transfer α particles and a recoiled lithium nucleus (7Li) that selectively destroys the DNA helix in tumor cells.
Kiyoshi Takahara +3 more
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Boron encapsulated in a liposome can be used for combinational neutron capture therapy
Nature Communications, 2022 Boron neutron capture therapy is a type of cancer therapy but is associated with insufficient boron delivery and with poor biocompatibility. Here, the authors constructed boronated lipids to generate - boronsome - and show the system can reduce tumour ...
Jiyuan Li +8 more
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The basis and advances in clinical application of boron neutron capture therapy
Radiation Oncology, 2021 Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He +9 more
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