Results 11 to 20 of about 5,770 (216)

The three dimensional map of dose components in a head phantom for boron neutron capture therapy [PDF]

Nuclear Technology and Radiation Protection, 2013
The in-phantom measurement of physical dose distribution and construction of a convenient phantom is very important for boron neutron capture therapy planning validation.
Bavarnegin Elham, Sadremomtaz Alireza, Khalafi Hossein   +2 more
doaj   +2 more sources

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine

Biology, 2021
Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment exploiting a nuclear reaction occurring in tumor cells [...]
Silva Bortolussi, Yuan-Hao Liu, Ignacio Porras   +2 more
doaj   +2 more sources

Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment

Cells, 2022
Boron neutron capture therapy is a low-invasive cancer therapy based on the neutron fission process that occurs upon thermal neutron irradiation of 10B-containing compounds; this process causes the release of alpha particles that selectively damage ...
Giorgia Ailuno, Alice Balboni, Gabriele Caviglioli, Francesco Lai, Federica Barbieri, Irene Dellacasagrande, Tullio Florio, Sara Baldassari   +7 more
doaj   +2 more sources

Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights

Proceedings
Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Hiroki Tanaka, Naonori Hu, Toshihiro Takami, Masahiko Wanibuchi   +9 more
doaj   +2 more sources

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Journal of Pharmacological Sciences, 2019
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by ...
Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai   +12 more
doaj   +2 more sources

Neutron flux evaluation model provided in the accelerator-based boron neutron capture therapy system employing a solid-state lithium target

Scientific Reports, 2021
An accelerator-based boron neutron capture therapy (BNCT) system employing a solid-state Li target can achieve sufficient neutron flux for treatment although the neutron flux is reduced over the lifetime of its target.
Satoshi Nakamura, Hiroshi Igaki, Masashi Ito, Shoji Imamichi, Tairo Kashihara, Hiroyuki Okamoto, Shie Nishioka, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Mihiro Takemori, Yoshihisa Abe, Tomoya Kaneda, Kana Takahashi, Koji Inaba, Kae Okuma, Naoya Murakami, Yuko Nakayama, Mitsuko Masutani, Teiji Nishio, Jun Itami   +20 more
doaj   +1 more source

Carborane Polypeptide Derivatives for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
The design and application of carborane polypeptide derivatives have attracted more and more attention, especially as boron carrier in the treatment of malignant tumors(BNCT).
HAN Yi, LI Feng-lin, LUO Zhi-fu
doaj   +1 more source

In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

Scientific Reports, 2022
While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly relies on gamma rays and Auger electrons ...
Woonghee Lee, Kyung Won Kim, Jeong Eun Lim, Swarbhanu Sarkar, Jung Young Kim, Yongmin Chang, Jeongsoo Yoo   +6 more
doaj   +1 more source

Homocystamide Conjugates of Human Serum Albumin as a Platform to Prepare Bimodal Multidrug Delivery Systems for Boron Neutron Capture Therapy

Molecules, 2021
Boron neutron capture therapy is a unique form of adjuvant cancer therapy for various malignancies including malignant gliomas. The conjugation of boron compounds and human serum albumin (HSA)—a carrier protein with a long plasma half-life—is expected to
Tatyana Popova, Maya A. Dymova, Ludmila S. Koroleva, Olga D. Zakharova, Vladimir A. Lisitskiy, Valeria I. Raskolupova, Tatiana Sycheva, Sergei Taskaev, Vladimir N. Silnikov, Tatyana S. Godovikova   +9 more
doaj   +1 more source

Correlation between L‐amino acid transporter 1 expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine accumulation in humans

Cancer Medicine, 2023
Background The correlation between L‐type amino acid transporter 1 (LAT1) expression and 4‐borono‐2‐18F‐fluoro‐phenylalanine (18F‐FBPA) accumulation in humans remains unclear.
Tairo Kashihara, Taisuke Mori, Tetsu Nakaichi, Satoshi Nakamura, Kimiteru Ito, Hiroaki Kurihara, Masahiko Kusumoto, Jun Itami, Seiichi Yoshimoto, Hiroshi Igaki   +9 more
doaj   +1 more source