Results 1 to 10 of about 3,705 (207)

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT). [PDF]

Pharmaceutics, 2023
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT). The boronated amino acids synthesized thus far for BNCT investigations can be classified into two categories based on the source of boron: boronic acids
Järvinen J, Pulkkinen H, Rautio J, Timonen JM.   +3 more
europepmc   +6 more sources

Advances in Boron Neutron Capture Therapy (BNCT) for Recurrent Intracranial Meningioma. [PDF]

Int J Mol Sci, 2023
Meningiomas are the most frequently diagnosed primary intracranial tumors in adults. Surgical resection is preferred if the meningioma is accessible; for those that are not suitable for surgical resection, radiotherapy should be considered to improve local tumor control.
Lan TL, Lin CF, Lee YY, Lin KH, Chang FC, Lin SC, Lee JC, Chou FI, Peir JJ, Liu HM, Mu PF, Chen YW.   +11 more
europepmc   +5 more sources

Optimizing Boron Neutron Capture Therapy (BNCT) to Treat Cancer: An Updated Review on the Latest Developments on Boron Compounds and Strategies. [PDF]

Cancers (Basel), 2023
Optimizing Boron Neutron Capture Therapy (BNCT) to Treat Cancer: An Updated Review on the Latest Developments on Boron Compounds and StrategiesAndrea Monti Hughes 1 2, Naonori Hu 3 4Affiliations1Radiation Pathology Division, Department Radiobiology ...
Monti Hughes A, Hu N.
europepmc   +4 more sources

Integrating measurement and simulation for evaluation of patient-specific whole-body dosimetry in clinical BNCT. [PDF]

Med Phys
Abstract Background Boron neutron capture therapy (BNCT) is a treatment modality that utilises high intensity neutron beam in combination with a boron drug to target cancer cells at the cellular level. Despite decades of research in this field, there are very few reports on out‐of‐field patient dose of BNCT.
Kakino R, Hu N, Sasaki A, Nojiri M, Yoshino Y, Takeno S, Aihara T, Matsubayashi N, Takata T, Tanaka H, Nihei K, Ono K.   +11 more
europepmc   +2 more sources

Core clinical procedures and efficacy-enhancing strategies in boron neutron capture therapy [PDF]

Discover Oncology
Boron Neutron Capture Therapy (BNCT) is a binary targeted radiotherapy modality based on nuclear capture reactions. This technique exploits the tumor-targeting capability of boron compounds and their high thermal neutron capture cross-section, inducing ...
Qinqin Ma, Pengcheng Zhang, Huanyu Zhang, Hongxin Su, Tanglong Zhang, Zhuoya Zhang, Yuan Pan, Ruiming Chen, Juntao Ran   +8 more
doaj   +2 more sources

In Vivo Application of Carboranes for Boron Neutron Capture Therapy (BNCT): Structure, Formulation and Analytical Methods for Detection. [PDF]

Cancers (Basel), 2023
Marforio TD, Carboni A, Calvaresi M.
europepmc   +2 more sources

Exploring the Biological and Physical Basis of Boron Neutron Capture Therapy (BNCT) as a Promising Treatment Frontier in Breast Cancer. [PDF]

Cancers (Basel), 2022
Seneviratne D, Advani P, Trifiletti DM, Chumsri S, Beltran CJ, Bush AF, Vallow LA.   +6 more
europepmc   +2 more sources

Systemic Immunity Triggered by Boron Neutron Capture Therapy via Manganese-Borate Complex [PDF]

Materials Today Bio
Conventional radiotherapy compromises antitumor immunity through collateral damage to immune cells. While boron neutron capture therapy (BNCT) enables tumor-selective 10B (n, α) 7Li reactions, clinical agents like boronophenylalanine (BPA) suffer from ...
Chang Chen, Chao Wang, Lin Zhang, Yue Yu, Xu Li, Wenhao Pan, Yuanyu Liu, Jiheng Wang, Maosong Yang, Bing Hong, Xingguang Hu, Jichao Wang, Yuzhong Qian, Xiancai Meng, Yinghuai Zhu, Zhigang Liu, Shaobo Huang, Lizheng Liang, Jinhui Wu, Yang Liu   +19 more
doaj   +2 more sources

Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry. [PDF]

Int J Mol Sci, 2023
Flieger S, Takagaki M, Kondo N, Lutz MR, Gupta Y, Ueda H, Sakurai Y, Moran G, Kempaiah P, Hosmane N, Suzuki M, Becker DP.   +11 more
europepmc   +2 more sources

Carborane Polypeptide Derivatives for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
The design and application of carborane polypeptide derivatives have attracted more and more attention, especially as boron carrier in the treatment of malignant tumors(BNCT).
HAN Yi, LI Feng-lin, LUO Zhi-fu
doaj   +1 more source