Results 1 to 10 of about 5,439 (211)

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT). [PDF]

Pharmaceutics, 2023
Interest in the design of boronated amino acids has emerged, partly due to the utilization of boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron Capture Therapy (BNCT). The boronated amino acids synthesized thus far for BNCT investigations can be classified into two categories based on the source of boron: boronic acids
Järvinen J, Pulkkinen H, Rautio J, Timonen JM.   +3 more
europepmc   +6 more sources

Advances in Boron Neutron Capture Therapy (BNCT) for Recurrent Intracranial Meningioma. [PDF]

Int J Mol Sci, 2023
Meningiomas are the most frequently diagnosed primary intracranial tumors in adults. Surgical resection is preferred if the meningioma is accessible; for those that are not suitable for surgical resection, radiotherapy should be considered to improve local tumor control.
Lan TL, Lin CF, Lee YY, Lin KH, Chang FC, Lin SC, Lee JC, Chou FI, Peir JJ, Liu HM, Mu PF, Chen YW.   +11 more
europepmc   +5 more sources

The Birmingham Boron Neutron Capture Therapy (BNCT) Project: [PDF]

Clinical Oncology, 2011
This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compound ...
S. Green, B. Phoenix, A.J. Mill, M. Hill, M.W. Charles, J. Thompson, B. Jones, D. Ngoga, A. Detta, N.D. James, J. Doran, N. Graham, Z. Ghani, C. Wojnecki, G. Halbert, M. Elliott, S. Ford, T.M.T. Sheehan, J. Vickerman, N. Lockyer, G. Croswell, A. Boddy, A. King, G.S. Cruickshank   +23 more
openaire   +2 more sources

Core clinical procedures and efficacy-enhancing strategies in boron neutron capture therapy [PDF]

Discover Oncology
Boron Neutron Capture Therapy (BNCT) is a binary targeted radiotherapy modality based on nuclear capture reactions. This technique exploits the tumor-targeting capability of boron compounds and their high thermal neutron capture cross-section, inducing ...
Qinqin Ma, Pengcheng Zhang, Huanyu Zhang, Hongxin Su, Tanglong Zhang, Zhuoya Zhang, Yuan Pan, Ruiming Chen, Juntao Ran   +8 more
doaj   +2 more sources

Systemic Immunity Triggered by Boron Neutron Capture Therapy via Manganese-Borate Complex [PDF]

Materials Today Bio
Conventional radiotherapy compromises antitumor immunity through collateral damage to immune cells. While boron neutron capture therapy (BNCT) enables tumor-selective 10B (n, α) 7Li reactions, clinical agents like boronophenylalanine (BPA) suffer from ...
Chang Chen, Chao Wang, Lin Zhang, Yue Yu, Xu Li, Wenhao Pan, Yuanyu Liu, Jiheng Wang, Maosong Yang, Bing Hong, Xingguang Hu, Jichao Wang, Yuzhong Qian, Xiancai Meng, Yinghuai Zhu, Zhigang Liu, Shaobo Huang, Lizheng Liang, Jinhui Wu, Yang Liu   +19 more
doaj   +2 more sources

Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights

Proceedings
Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Hiroki Tanaka, Naonori Hu, Toshihiro Takami, Masahiko Wanibuchi   +9 more
doaj   +2 more sources

Development and evaluation of surface-guided patient position system for boron neutron capture therapy [PDF]

Scientific Reports
Boron Neutron Capture Therapy (BNCT) is an advanced form of radiotherapy that uses the neutron capture reaction of boron-10 to selectively destroy cancer cells.
Jiang Chen, Qiao-Lin Xie, Jing-Jing Ping, Ting-Ting Hou, Yuan-Hao Liu   +4 more
doaj   +2 more sources

Carborane Polypeptide Derivatives for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
The design and application of carborane polypeptide derivatives have attracted more and more attention, especially as boron carrier in the treatment of malignant tumors(BNCT).
HAN Yi, LI Feng-lin, LUO Zhi-fu
doaj   +1 more source

In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

Scientific Reports, 2022
While boron neutron capture therapy (BNCT) depends primarily on the short flight range of the alpha particles emitted by the boron neutron capture reaction, gadolinium neutron capture therapy (GdNCT) mainly relies on gamma rays and Auger electrons ...
Woonghee Lee, Kyung Won Kim, Jeong Eun Lim, Swarbhanu Sarkar, Jung Young Kim, Yongmin Chang, Jeongsoo Yoo   +6 more
doaj   +1 more source

Construction of targeted 10B delivery agents and their uptake in gastric and pancreatic cancer cells

Frontiers in Oncology, 2023
Boron Neutron Capture Therapy (BNCT) is a new binary radiation therapy for tumor tissue, which kills tumor cells with neutron capture reaction. Boron neutron capture therapy has become a technical means for glioma, melanoma, and other diseases has been ...
Song Wang, Song Wang, Zhengchao Zhang, Zhengchao Zhang, Lele Miao, Lele Miao, Jiaxing Zhang, Jiaxing Zhang, Futian Tang, Futian Tang, Muzhou Teng, Muzhou Teng, Yumin Li, Yumin Li   +13 more
doaj   +1 more source