Results 1 to 10 of about 1,846 (126)

Emerging agents for boron neutron capture therapy: Biomolecular carriers paving the way for precision radiotherapy. [PDF]

Precis Radiat Oncol
Boron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chen C, Yang M, Wang J, Zhang L, Huang S, Xu X, Liu Y.   +6 more
europepmc   +2 more sources

Advances in Boron Neutron Capture Therapy (BNCT) for Recurrent Intracranial Meningioma [PDF]

International Journal of Molecular Sciences, 2023
Peir Jinn-Jer, Yi Yen Lee, Tien-Li Lan
exaly   +2 more sources

Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT) [PDF]

Pharmaceutics, 2023
Juri Timonen, Jarkko Rautio, Júulia Jarvinen   +2 more
exaly   +2 more sources

Core clinical procedures and efficacy-enhancing strategies in boron neutron capture therapy [PDF]

Discover Oncology
Boron Neutron Capture Therapy (BNCT) is a binary targeted radiotherapy modality based on nuclear capture reactions. This technique exploits the tumor-targeting capability of boron compounds and their high thermal neutron capture cross-section, inducing ...
Qinqin Ma, Pengcheng Zhang, Huanyu Zhang, Hongxin Su, Tanglong Zhang, Zhuoya Zhang, Yuan Pan, Ruiming Chen, Juntao Ran   +8 more
doaj   +2 more sources

Optimizing Boron Neutron Capture Therapy (BNCT) to Treat Cancer: An Updated Review on the Latest Developments on Boron Compounds and Strategies [PDF]

Cancers, 2023
Andrea Monti Hughes, Naonori Hu, Monti Hughes Andrea   +2 more
exaly   +2 more sources

Boron-10 carriers and their applications in boron neutron capture therapy. [PDF]

Precis Radiat Oncol
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Tang D, Shi M, Mao Z, Chen W, Li X, Zhao XY, Liu Z, Xu X.   +7 more
europepmc   +2 more sources

Exploring the Biological and Physical Basis of Boron Neutron Capture Therapy (BNCT) as a Promising Treatment Frontier in Breast Cancer [PDF]

Cancers, 2022
Saranya Chumsri, Danushka Seneviratne, Daniel Trifiletti   +2 more
exaly   +2 more sources

In Vivo Application of Carboranes for Boron Neutron Capture Therapy (BNCT): Structure, Formulation and Analytical Methods for Detection [PDF]

Cancers, 2023
Matteo Calvaresi, Tainah Dorina Marforio, Andrea Carboni   +2 more
exaly   +2 more sources

Chordoma Treatment with Boron Neutron Capture Therapy (BNCT): Experimental Insights

Proceedings
Boron Neutron Capture Therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Hiroki Tanaka, Naonori Hu, Toshihiro Takami, Masahiko Wanibuchi   +9 more
doaj   +3 more sources

Systemic Immunity Triggered by Boron Neutron Capture Therapy via Manganese-Borate Complex [PDF]

Materials Today Bio
Conventional radiotherapy compromises antitumor immunity through collateral damage to immune cells. While boron neutron capture therapy (BNCT) enables tumor-selective 10B (n, α) 7Li reactions, clinical agents like boronophenylalanine (BPA) suffer from ...
Chang Chen, Chao Wang, Lin Zhang, Yue Yu, Xu Li, Wenhao Pan, Yuanyu Liu, Jiheng Wang, Maosong Yang, Bing Hong, Xingguang Hu, Jichao Wang, Yuzhong Qian, Xiancai Meng, Yinghuai Zhu, Zhigang Liu, Shaobo Huang, Lizheng Liang, Jinhui Wu, Yang Liu   +19 more
doaj   +2 more sources