Results 31 to 40 of about 3,705 (207)

A Review of Boron Neutron Capture Therapy: Its History and Current Challenges

, 2022
MECHANISM OF ACTION: External beam, whether with photons or particles, remains as the most common type of radiation therapy. The main drawback is that radiation deposits dose in healthy tissue before reaching its target.
Seldon, Crystal, Butkus, Michael, Sauerwein, Wolfgang, Giap, Huan B., Jin, Will H.   +4 more
core   +1 more source

Clinical trials for treating recurrent head and neck cancer with boron neutron capture therapy using the Tsing-Hua Open Pool Reactor

Cancer Communications, 2018
Head and neck (HN) cancer is an endemic disease in Taiwan, China. Locally recurrent HN cancer after full-dose irradiation poses a therapeutic challenge, and boron neutron capture therapy (BNCT) may be a solution that could provide durable local control ...
Ling-Wei Wang, Yen-Wan Hsueh Liu, Fong-In Chou, Shiang-Huei Jiang   +3 more
doaj   +1 more source

First Attempt of Boron Neutron Capture Therapy (BNCT) for Hepatocellular Carcinoma [PDF]

Japanese Journal of Clinical Oncology, 2007
A 60-year-old man with multiple hepatocellular carcinomas (HCCs) was enrolled as the first patient in a pilot study for treating multiple liver tumors with boron neutron capture therapy (BNCT). Because of compromised liver function, the multiple tumors in the right liver lobe were treated with BNCT and those in the left lobe with hepatic arterial ...
Minoru, Suzuki, Yoshinori, Sakurai, Satoru, Hagiwara, Shinichiro, Masunaga, Yuko, Kinashi, Kenji, Nagata, Akira, Maruhashi, Masatoshi, Kudo, Koji, Ono   +8 more
openaire   +2 more sources

Site‐Selective B─H Activation via HAT Toward Xanthyl‐closo‐Carboranes as Bench‐Stable Precursors of Organosulfur Boron Clusters

Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.
A light mediated direct regioselective B─H functionalization, via hydrogen atom transfer (HAT), is described. Unexplored xanthyl‐closo‐carboranes as novel bench‐stable and versatile platforms to access sulfur‐containing boron clusters are reported for the first time.
Marco Rusconi, Eugenia Magi, Polyssena Renzi, Emanuele Azzi, Valeria Lagostina, Enrico Salvadori, Mario Chiesa, Birgit Hischa, Giovanni Ghigo, Annamaria Deagostino   +9 more
wiley   +2 more sources

7. Neutron Capture Therapy [PDF]

, 2021
In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2020/ProgRep2020.htmlCO7-1 Establichment of a novel mutation breeding using Boron Neutron Capture Reaction (BNCR ...

core  

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

Journal of Pharmacological Sciences, 2019
Boron neutron capture therapy (BNCT) is a radiotherapy utilizing the neutron capture and nuclear fission reaction of 10B taken up into tumor cells. The most commonly used boron agent in BNCT, p-borono-l-phenylalanine (BPA), is accumulated in tumors by ...
Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai   +12 more
doaj   +1 more source

Recent Advances in the Synthesis of High Boron-Loaded Nucleic Acids for BNCT

Frontiers in Chemistry, 2021
Boron clusters attract considerable attention as promising therapeutic tools for boron neutron capture therapy (BNCT). They combine high boron content with high chemical and biological stability, biorthogonality, and low toxicity.
Darya Sergeevna Novopashina, Mariya Alexandrovna Vorobyeva, Alya Venyaminova   +2 more
doaj   +1 more source

Assesment of Boron Neutron Capture Therapy (BNCT): Compact Neutron Generators

, 2018
Boron  Neutron Capture Therapy (BNCT)  is an effective and promising treatment          of tumour types which are resistant to conventional therapies.
Sardjono, Yohannes, Wahyuni, Nur Setyo
core   +1 more source

Multi-Functional Boron-Delivery Agents for Boron Neutron Capture Therapy of Cancers

, 2023
Boron neutron capture therapy (BNCT) is a binary cancer treatment that involves the irradiation of 10B-containing tumors with low-energy neutrons (thermal or epithermal).
Vicente, Maria da Graça H., Oloo, Sebastian O., Kevin M. Smith, Sebastian O. Oloo, Maria da Graça H. Vicente, Smith, Kevin M.   +5 more
core   +1 more source

Clinical application of boron neutron capture therapy for cancer treatment: A systematic review

Precision Radiation Oncology
Boron neutron capture therapy (BNCT) combines boron drug delivery and heavy‐ion therapy. The key factors in the application of BNCT are high‐quality neutron beams and boron‐containing compounds.
Ling Zhou, Yuming Chen, Meng Peng, Xiumao Yin, Huanqing Liang, Jieming Mo, Wan Zhang, Zhigang Liu   +7 more
doaj   +1 more source