Results 51 to 60 of about 5,439 (211)

The Anti-Tumor Effect of Boron Neutron Capture Therapy in Glioblastoma Subcutaneous Xenograft Model Using the Proton Linear Accelerator-Based BNCT System in Korea

Life, 2022
Boron neutron capture therapy (BNCT) is a radiation therapy that selectively kills cancer cells and is being actively researched and developed around the world.
Il Hyeok Seo, Jeongwoo Lee, Dasom Na, Hyunhye Kyung, Jieun Yang, Sangbong Lee, Sang June Jeon, Jae Won Choi, Kyu Young Lee, Jungyu Yi, Jaehwan Han, Mooyoung Yoo, Se Hyun Kim   +12 more
doaj   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Boron neutron capture therapy for melanoma: recent advances and future prospects

Frontiers in Oncology
Boron neutron capture therapy (BNCT) is a unique radiotherapy modality that targets and destroys selectively tumor cells that have absorbed boron, while leaving surrounding healthy cells unharmed.
Yuanyang Sun, Yun Wang, Shukun Mu, Xiaofeng Wu, Suchun Yu, Zhongming Wang   +5 more
doaj   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Optimization of Beam Shaping Assembly design for Boron Neutron Capture Therapy based on a transportable proton accelerator

Alexandria Engineering Journal, 2018
The optimization of a Beam Shaping Assembly design for Boron Neutron Capture Therapy (BNCT), based on a commercial available proton accelerator, has been simulated.
Jacob G. Fantidis, G. Nicolaou
doaj   +1 more source

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli, Clara M.G. de Faria, Veronica Torresan, Maria Assunta Lacavalla, Mattia Cattelan, Denis Badocco, Paolo Pastore, Pasquina Marzola, Laura Cansolino, Cinzia Ferrari, Ian Postuma, Riccardo Vago, Silva Bortolussi, Antonello E. Spinelli, Daniel Forrer, Vincenzo Amendola   +15 more
wiley   +1 more source

Sviluppo e applicazioni della boron neutron capture therapy [PDF]

, 2017
La Boron Neutron Capture Therapy è una tecnica terapeutica altamente selettiva, utilizzata in oncologia, che si basa sulla reazione di cattura neutronica 10B(n,α)7Li .
Guidi, Claretta
core  

The prospects of using IRT-T reactor experimantal facilities for boron neutron capture therapy research [PDF]

, 2012
Investigation on the use of IRT-T research reactor experimental facilities for Boron Neutron Capture Therapy (BNCT) applications was performed by calculating beam parameters at the horizontal channels' exits.
Молодов, П. А., Аникин, Михаил Николаевич, Наймушин, Артем Георгиевич   +2 more
core   +1 more source

Engineering Hybrid Polymeric Gd2O3 Nanoparticles for Tumor‐Targeted Neutron Capture Therapy

ChemNanoMat, Volume 12, Issue 4, April 2026.
Neutron capture therapy (NCT) stands as a transformative approach for precision oncology. The principle relies on tumor‐targeted isotopes, such as boron‐10 (10B) and gadolinium‐157 (157Gd), for generating cytotoxic high energy particles upon thermal neutron irradiation.
Xiwen Chen, Pengwen Chen, Yoshihiro Tachihara, Changyuan Qin, Xuan Hou, Thahomina Khan, Nobuhiro Nitta, Masashi Yanagawa, Yuriko Sakurai, Minoru Suzuki, Shin‐Ichiro Masunaga, Hiroki Tanaka, Yoshinori Sakurai, Hiroyuki Takahashi, Ichio Aoki, Hironobu Yanagie, Horacio Cabral   +16 more
wiley   +1 more source

Finnish Dosimetric Practice for Epithermal Neutron Beam Dosimetry in Boron Neutron Capture Therapy [PDF]

, 2009
Boron neutron capture therapy (BNCT) is a form of chemically targeted radiotherapy that utilises the high neutron capture cross-section of boron-10 isotope to achieve a preferential dose increase in the tumour.
Uusi-Simola, Jouni
core