Results 51 to 60 of about 3,705 (207)

The Anti-Tumor Effect of Boron Neutron Capture Therapy in Glioblastoma Subcutaneous Xenograft Model Using the Proton Linear Accelerator-Based BNCT System in Korea

Life, 2022
Boron neutron capture therapy (BNCT) is a radiation therapy that selectively kills cancer cells and is being actively researched and developed around the world.
Il Hyeok Seo, Jeongwoo Lee, Dasom Na, Hyunhye Kyung, Jieun Yang, Sangbong Lee, Sang June Jeon, Jae Won Choi, Kyu Young Lee, Jungyu Yi, Jaehwan Han, Mooyoung Yoo, Se Hyun Kim   +12 more
doaj   +1 more source

Development of thermal neutron moderator for testing boron agents for Boron Neutron Capture Therapy (BNCT)

, 2019
We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan ...
999429, Ichikawa, G., Ogawara, Ryo, 999427, 999428, Suda, Mitsuru, Ishikawa, A., Tsuyoshi, Hamano, Ryo, Ogawara, 999430, 999431, Watanabe, K., Kiyanagi, Y., 999418, 999419, 999417, Tsuchida, K., Yoshihashi, S., Igawa, K., Hamano, Tsuyoshi, 999421, 999422, Mitsuru, Suda, 999420, 999425, 999426, 999423, Uritani, A., Hirata, Y., 999424   +29 more
core   +1 more source

Transporter‐Associated Therapeutic Efficacy of an SMVT‐Targeted Boron Carrier in Boron Neutron Capture Therapy

Cancer Science, EarlyView.
The transporter‐associated BNCT strategy using BBCIP with or without BPA according to tumor transporter characteristics. BPA showed greater efficacy in LAT1‐dominant F98 glioma, whereas BBCIP was more effective in SMVT‐high CRL1666 tumors, suggesting the potential utility of transporter‐based boron carrier selection in BNCT.
Kenichiro Eza, Kohei Tsujino, Rina Shidoh‐Kazuki, Yoshiki Fujikawa, Hideki Kashiwagi, Gen Futamura, Ryo Hiramatsu, Toshihiro Takami, Masahiko Wanibuchi, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Kai Nishimura, Shota Tanaka, Hiroyuki Nakamura, Shinji Kawabata   +15 more
wiley   +1 more source

Boron neutron capture therapy for melanoma: recent advances and future prospects

Frontiers in Oncology
Boron neutron capture therapy (BNCT) is a unique radiotherapy modality that targets and destroys selectively tumor cells that have absorbed boron, while leaving surrounding healthy cells unharmed.
Yuanyang Sun, Yun Wang, Shukun Mu, Xiaofeng Wu, Suchun Yu, Zhongming Wang   +5 more
doaj   +1 more source

Optimization of Beam Shaping Assembly design for Boron Neutron Capture Therapy based on a transportable proton accelerator

Alexandria Engineering Journal, 2018
The optimization of a Beam Shaping Assembly design for Boron Neutron Capture Therapy (BNCT), based on a commercial available proton accelerator, has been simulated.
Jacob G. Fantidis, G. Nicolaou
doaj   +1 more source

Boron neutron capture therapy (BNCT) in Finland:Technological and physical prospects after 20 years of experiences

, 2013
Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy method developed to treat patients with certain malignant tumours. To date, over 300 treatments have been carried out at the Finnish BNCT facility in various on-going and past clinical trials.
Savolainen, Sauli, Koivunoro, Hanna, Timonen, Marjut, Kuusela, Linda, Auterinen, Iiro, Serén, Tom, Heikkinen, Sami, Lönnroth, Nadja, Kotiluoto, Petri; id_orcid, Salli, Eero, Välimäki, Petteri, Kosunen, Antti, Uusi-Simola, Jouni, Hyvönen, Heini, Seppälä, Tiina, Kortesniemi, Mika, Kuronen, Antti, Reijonen, Vappu   +17 more
core   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

CYTOPATHIC EFFECTS OF ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY ON HUMAN GLIOBLASTOMA CELLS

Сибирский онкологический журнал, 2019
Boron neutron capture therapy (BNCT) is a targeted therapy based on a selective damage to cancer cells due to the interaction between boron-10 isotope and neutron.
V. A. Byvaltsev, E. L. Zavjalov, V. V. Kanygin, A. I. Kasatova, A. I. Kichigin, I. A. Razumov, T. V. Sycheva, S. Yu. Taskaev   +7 more
doaj   +1 more source

Measurement of the applicability of various experimental materials in a medically relevant reactor neutron source part two: Study of H3BO3 and B-DTPA under neutron irradiation

Nuclear Engineering and Technology, 2023
Experiments related to Boron Neutron Capture Therapy (BNCT) accomplished at the Institute of Nuclear Techniques (INT), Budapest University of Technology and Economics (TUB) are presented.
Ezddin Hutli, Peter Zagyvai
doaj   +1 more source

A new perspective on radiotherapy in the comprehensive treatment of cancer

Precision Radiation Oncology, Volume 10, Issue 2, Page 165-183, June 2026.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma, Hongxuan Yu, Shijie Shang, Shixin Shan, Dawei Chen   +4 more
wiley   +1 more source