Results 61 to 70 of about 3,705 (207)

Emerging agents for boron neutron capture therapy: Biomolecular carriers paving the way for precision radiotherapy

Precision Radiation Oncology, Volume 10, Issue 2, Page 254-264, June 2026.
Boron neutron capture therapy (BNCT) requires key non‐negotiable technical criteria: megadose administration, precise tumor‐specific targeting, favorable biocompatibility, and sustained tumor retention. Overcoming these interconnected challenges fundamentally depends on biomolecular carriers, which are critical for translating the therapeutic potential
Chang Chen, Maosong Yang, Jiheng Wang, Ling Zhang, Shaobo Huang, Xiao Xu, Yang Liu   +6 more
wiley   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Compton imaging for dosimetry and real time monitoring in boron neutron capture therapy [PDF]

EPJ Web of Conferences
Boron Neutron Capture Therapy (BNCT) is an emerging radiotherapy technique that exploits the high neutron capture cross-section of 10B to deliver targeted high-LET radiation to tumor cells while sparing surrounding healthy tissue.
Torres-Sánchez Pablo, Valladares Sebastián, Balibrea-Correa Javier, Lerendegui-Marco Jorge, Babiano-Suarez Víctor, Gameiro Bernardo, Ladarescu Ion, Michelagnoli Caterina, Daugas Jean-Michel, Koester Ulli, Álvarez-Rodríguez Patricia, Méndez-Malagón Cristina, Porras-Quesada Maribel, Pedrosa-Rivera María, Ruiz-Magaña M. José, Ruiz-Ruiz Carmen, Porras Ignacio, Pardo César Domingo   +17 more
doaj   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Exploring BNCT as a Novel Approach for Metastatic Spinal Tumor Management

Proceedings
[Background] Boron neutron capture therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Ryo Kayama, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Toshihiro Takami, Masahiko Wanibuchi   +13 more
doaj   +1 more source

7. Neutron Capture Therapy [PDF]

, 2022
In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2021/ProgRep2021.htmlCO7-1 Synthesis and evaluation of a novel boron neutron capture therapy agent/ H. Kimura and M.

core  

Advances in boron neutron capture therapy (BNCT) at kyoto university - From reactor-based BNCT to accelerator-based BNCT [PDF]

, 2015
First online: 28 July 2015At the Kyoto University Research Reactor Institute (KURRI), a clinical study of boron neutron capture therapy (BNCT) using a neutron irradiation facility installed at the research nuclear reactor has been regularly performed ...
Maruhashi, Akira, Kondo, Natsuko, Watanabe, Tsubasa, Masunaga, Shinichiro, Ono, Koji, Narabayashi, Masaru, Kinashi, Yuko, Suzuki, Minoru, Sakurai, Yoshinori, Fujimoto, Nozomi, Tanaka, Hiroki, Takata, Takushi, Nakagawa, Yosuke   +12 more
core   +1 more source

Microdosimetry in BNCT

Precision Radiation Oncology, EarlyView.
Gustavo A. Santa Cruz
wiley   +1 more source

Development of a practical and high‐speed deep learning‐based dose calculation model in boron neutron capture therapy for head and neck cancer

Medical Physics, Volume 53, Issue 5, May 2026.
Abstract Background In boron neutron capture therapy (BNCT), Monte Carlo (MC) dose calculations are commonly employed because of the complicated neutron reactions. However, MC dose calculations are generally time‐consuming. Recently, deep learning (DL)‐based dose prediction/calculation has attracted increasing attention; however, the applications of DL
Ryohei Kato, Noriyuki Kadoya, Takahiro Kato, Akihiko Takeuchi, Shinya Komori, Keiichi Jingu, Yoshihiro Takai   +6 more
wiley   +1 more source

MEASUREMENT OF NEUTRON SPATIAL DISTRIBUTION OF THE BNCT EPITHERMAL BEAM AT THE REACTOR LVR-15

Acta Polytechnica CTU Proceedings, 2016
In this study, a measurements of neutron field using a special positioning device with a 6Li + Si detector and image plate is described. The measurements were provided for Boron Neutron Capture Therapy (BNCT) channel of the LVR-15 reactor in the Research
Michaela Rabochová, Miroslav Vinš, Jaroslav Šoltés, Božena Michalcová   +3 more
doaj   +1 more source