Results 61 to 70 of about 3,740,560 (195)

A coarse‐to‐fine framework combining deep learning and Monte Carlo for BNCT patient position optimization toward inverse planning

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Boron Neutron Capture Therapy (BNCT) utilizes high linear energy transfer (LET) charged particles from the 10B(n,α)7Li reaction to selectively destroy tumor cells. Unlike conventional radiation therapy, BNCT facilities rely on fixed beam ports, making patient positioning critical in treatment planning.
Yoonho Na, Chang‐min Lee, Kyuri Kim, Hyungjoo Cho, Jimin Lee, Sung‐Joon Ye   +5 more
wiley   +1 more source

CYTOPATHIC EFFECTS OF ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY ON HUMAN GLIOBLASTOMA CELLS

Сибирский онкологический журнал, 2019
Boron neutron capture therapy (BNCT) is a targeted therapy based on a selective damage to cancer cells due to the interaction between boron-10 isotope and neutron.
V. A. Byvaltsev, E. L. Zavjalov, V. V. Kanygin, A. I. Kasatova, A. I. Kichigin, I. A. Razumov, T. V. Sycheva, S. Yu. Taskaev   +7 more
doaj   +1 more source

Multi‐fidelity Monte Carlo fusion for BNCT dose calculation using a dual‐branch network

Medical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Boron neutron capture therapy (BNCT) is a binary radiotherapy that selectively kills tumor cells. Its clinical implementation relies on Monte Carlo (MC)‐based treatment planning systems, which are time‐consuming and limit clinical workflow efficiency.
Leiming Li, Xin Hong, Yongquan Wang, Gan Huang, Zhiqiang Wu, Yingjie Xiao, Hiroki Tanaka, Hiroshi Watabe   +7 more
wiley   +1 more source

Development of thermal neutron moderator for testing boron agents for Boron Neutron Capture Therapy (BNCT)

, 2019
We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan ...
999429, Ichikawa, G., Ogawara, Ryo, 999427, 999428, Suda, Mitsuru, Ishikawa, A., Tsuyoshi, Hamano, Ryo, Ogawara, 999430, 999431, Watanabe, K., Kiyanagi, Y., 999418, 999419, 999417, Tsuchida, K., Yoshihashi, S., Igawa, K., Hamano, Tsuyoshi, 999421, 999422, Mitsuru, Suda, 999420, 999425, 999426, 999423, Uritani, A., Hirata, Y., 999424   +29 more
core   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

Small, Volume 22, Issue 46, 18 August 2026.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem, Hadi Shayesteh, Simindokht Zarei‐Shokat, Rokhsareh Bakhtiari, Sheyda Abedi‐Banaei, Zahra Sheikhlouiharzand, Parnia Mohebimanesh, Seyed Mohammad Amin Ojagh, Bahareh Bakhtiari, Ali Maleki, Theo G. M. van de Ven, Sohrab Zendehboudi, Ali Elkamel   +12 more
wiley   +1 more source

Core clinical procedures and efficacy-enhancing strategies in boron neutron capture therapy

Discover Oncology
Boron Neutron Capture Therapy (BNCT) is a binary targeted radiotherapy modality based on nuclear capture reactions. This technique exploits the tumor-targeting capability of boron compounds and their high thermal neutron capture cross-section, inducing ...
Qinqin Ma, Pengcheng Zhang, Huanyu Zhang, Hongxin Su, Tanglong Zhang, Zhuoya Zhang, Yuan Pan, Ruiming Chen, Juntao Ran   +8 more
doaj   +1 more source

Compton imaging for dosimetry and real time monitoring in boron neutron capture therapy [PDF]

EPJ Web of Conferences
Boron Neutron Capture Therapy (BNCT) is an emerging radiotherapy technique that exploits the high neutron capture cross-section of 10B to deliver targeted high-LET radiation to tumor cells while sparing surrounding healthy tissue.
Torres-Sánchez Pablo, Valladares Sebastián, Balibrea-Correa Javier, Lerendegui-Marco Jorge, Babiano-Suarez Víctor, Gameiro Bernardo, Ladarescu Ion, Michelagnoli Caterina, Daugas Jean-Michel, Koester Ulli, Álvarez-Rodríguez Patricia, Méndez-Malagón Cristina, Porras-Quesada Maribel, Pedrosa-Rivera María, Ruiz-Magaña M. José, Ruiz-Ruiz Carmen, Porras Ignacio, Pardo César Domingo   +17 more
doaj   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

Immunology &Cell Biology, Volume 104, Issue 7, Page 711-728, August 2026.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari, Farah Ahmady‐Nield, Amit Sharma, Ingo G. H. Schmidt‐Wolf, Jarek Maciaczyk, Rodney B. Luwor, Adrian A. Achuthan   +6 more
wiley   +1 more source

Exploring BNCT as a Novel Approach for Metastatic Spinal Tumor Management

Proceedings
[Background] Boron neutron capture therapy (BNCT) is a particle beam therapy that enables the precise targeting of tumors at the cellular level [...]
Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Ryo Kayama, Hideki Kashiwagi, Yusuke Fukuo, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Toshihiro Takami, Masahiko Wanibuchi   +13 more
doaj   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, Volume 13, Issue 39, 13 July 2026.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source