Results 41 to 50 of about 3,705 (207)

Research on the Design of the BNCT Neutron Beam Device Based on the New Pool-Type Research Reactor

Journal of Isotopes
Based on the design scheme of a new-type swimming pool research reactor，this paper conducts preliminary design for a variable-energy neutron beam facility for boron neutron capture therapy (BNCT).
Song LIANG, Xiaoliang CHEN, Yajie ZUO, Jianping XU   +3 more
doaj   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

7. Neutron Capture Therapy [PDF]

, 2023
In case that corrections are made, overwrite the modified version in the following web page: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2022/ProgRep2022.htmlCO7-1 Development of Alubmin Binding Gadolinium Complexes for MRI-Guided BNCT/ S.

core  

Boron Neutron Capture Therapy - A Literature Review [PDF]

Journal of Clinical and Diagnostic Research, 2016
Boron Neutron Capture Therapy (BNCT) is a radiation science which is emerging as a hopeful tool in treating cancer, by selectively concentrating boron compounds in tumour cells and then subjecting the tumour cells to epithermal neutron beam radiation ...
Kavitaa Nedunchezhian, Nalini Aswath, Manigandan Thiruppathy, Sarumathi Thirugnanamurthy   +3 more
doaj   +1 more source

Synthesis and Functional Properties of Fluorinated Phosphonate‐Substituted Porphyrins: Excellent Photosensitizers and Robust Precursors for Photoactive Langmuir–Schaefer Films

Chemistry – A European Journal, EarlyView.
This is a comprehensive study of new family of high functionalized meso‐tetraarylporphyrins. A synthetic approach to phosphonate‐substituted fluorinated porphyrins was developed. These compounds were investigated with respect to singlet oxygen generation and photostability.
Azhar Kechiche, Cyrille Monnereau, Chantal Andraud, Alla Bessmertnykh‐Lemeune, Yoann Rousselin, Andrey V. Cheprakov, Elizaveta V. Ermakova, Alexandra I. Zvyagina, Habib Nasri   +8 more
wiley   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

Dose prescription in boron neutron capture therapy

, 1994
Purpose: The purpose of this paper is to address some aspects of the many considerations that need to go into a dose prescription in boron neutron capture therapy (BNCT) for brain tumors; and to describe some methods to incorporate knowledge from animal ...
Blue, Thomas E., Wambersie, André, Gahbauer, Reinhard A., Gupta, Nilendu, 5th International Symposium on Neutron Capture Therapy   +4 more
core   +1 more source

Current development status of accelerator-based neutron source for boron neutron capture therapy

EPJ Techniques and Instrumentation, 2023
Recently, progress in technology for accelerator-based neutron sources has increased attention regarding boron neutron capture therapy (BNCT). BNCT is a type of radiotherapy that combines neutrons and boron drugs and is expected to be used in the ...
Hiroaki Kumada, Takeji Sakae, Hideyuki Sakurai   +2 more
doaj   +1 more source

Possibilities of boron neutron capture therapy in the treatment of malignant brain tumors

Вестник рентгенологии и радиологии, 2016
Boron neutron capture therapy (BNCT) that is of the highest attractiveness due to its selective action directly on malignant tumor cells is a promising approach to treating cancers.
V. V. Kanygin, A. I. Kichigin, N. V. Gubanova, S. Yu Taskaev   +3 more
doaj   +1 more source

Reference based simulation study of detector comparison for BNCT-SPECT imaging

Nuclear Engineering and Technology, 2020
To investigate the optimal detector material for prompt gamma imaging during boron neutron capture therapy, in this study, we evaluated the characteristic regarding radiation reaction of available detector materials using a Monte Carlo simulation ...
Moo-Sub Kim, Han-Back Shin, Min-Geon Choi, Hajime Monzen, Jae Goo Shim, Tae Suk Suh, Do-Kun Yoon   +6 more
doaj   +1 more source