Results 21 to 30 of about 5,439 (211)

Design of a scintillator-based prompt gamma camera for boron-neutron capture therapy: Comparison of SrI2 and GAGG using Monte-Carlo simulation

Nuclear Engineering and Technology, 2021
Boron–neutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutron reactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation is essential for ensuring the accuracy and safety of BNCT. We
Minho Kim, Bong Hwan Hong, Ilsung Cho, Chawon Park, Sun-Hong Min, Won Taek Hwang, Wonho Lee, Kyeong Min Kim   +7 more
doaj   +1 more source

Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine

Biology, 2021
Boron Neutron Capture Therapy (BNCT) is a binary radiation treatment exploiting a nuclear reaction occurring in tumor cells [...]
Silva Bortolussi, Yuan-Hao Liu, Ignacio Porras   +2 more
doaj   +1 more source

Biological Distribution in Patients of Boron Agent 4-Borono-L-Phenylalanine for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
Boron neutron capture therapy(BNCT) is a binary targeted radiation therapy in which neutron does not directly provide tumor dose. The dose produced by the 10B(n, α)7Li capture reaction will be deposited in tumor cells by using targeted 10B agents ...
ZHU Xia-yang, LIU Kai, SHAO Yu-jun, JIN Cong-jun, ZHAO Chun-yuan, CHONG Yi-zheng, GUO Zhi-bin, SUN Qi, LIU Zhi-bo, LIU Tong, ZHANG Zi-zhu   +10 more
doaj   +1 more source

Radiobiological response of U251MG, CHO-K1 and V79 cell lines to accelerator-based boron neutron capture therapy [PDF]

, 2017
In the current article, we provide in vitro efficacy evaluation of a unique accelerator-based neutron source, constructed at the Budker Institute of Nuclear Physics (Novosibirsk, Russian Federation), for boron neutron capture therapy (BNCT), which is ...
Isobe Tomonori, Kanygin Vladimir, Mathis Bryan J, Matsumura Akira, Mechetina Ludmila, Nakai Kei, Sato Eisuke, Taranin Alexander, Taskaev Sergey, Volkova Olga, Yamamoto Tetsuya, Zaboronok Alexander, ザボロノク アレクサンドル, マティス ブライアン　 ジェームズ, 松村 明, 磯辺 智範   +15 more
core   +2 more sources

Development and dosimetric evaluation of a freely deformable ⁶Li-based neutron shield for boron neutron capture therapy. [PDF]

Med Phys
Abstract Background Boron neutron capture therapy (BNCT) enables selective tumor irradiation by exploiting the high‐linear energy transfer particles generated from neutron interactions with 10B atoms. BNCT has been approved as an insurance‐covered medical treatment for recurrent head and neck cancer in Japan.
Hu N, Kakino R, Sasaki A, Nojiri M, Akita K, Yoshikawa S, Kohigashi Y, Yoshino Y, Takeno S, Aihara T, Takata T, Tanaka H, Nihei K, Ono K.   +13 more
europepmc   +2 more sources

The Role of BNCT in Breast Cancer Treatment

Atom Indonesia, 2019
Boron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer ...
B. Poedjomartono, Y. Sardjono, E. Meiyanto, H. Winarno   +3 more
doaj   +1 more source

Site‐Selective B─H Activation via HAT Toward Xanthyl‐closo‐Carboranes as Bench‐Stable Precursors of Organosulfur Boron Clusters

Angewandte Chemie, EarlyView.
A light mediated direct regioselective B─H functionalization, via hydrogen atom transfer (HAT), is described. Unexplored xanthyl‐closo‐carboranes as novel bench‐stable and versatile platforms to access sulfur‐containing boron clusters are reported for the first time.
Marco Rusconi, Eugenia Magi, Polyssena Renzi, Emanuele Azzi, Valeria Lagostina, Enrico Salvadori, Mario Chiesa, Birgit Hischa, Giovanni Ghigo, Annamaria Deagostino   +9 more
wiley   +2 more sources

Boron Neutron Capture Therapy (BNCT) using Compact Neutron generator

Indonesian Journal of Physics and Nuclear Applications, 2016
<span>Boron Neutron Capture Therapy (BNCT) must be appropriate with five criteria from IAEA. These criteria in order to prevent neutron beam output harm the patient. It can be by using Collimator of neutron source Compact Neutron Generator (CNG) and Monte Carlo simulation method with N particles 5 .CNG is developed by deuteriumtritium reaction (DT)
Anggraeni Dwi Susilowati, Kusminarto Kusminarto, Yohannes Sardjono   +2 more
openaire   +2 more sources

Principles and Clinical Applications of Boron Neutron Capture Therapy

Xiehe Yixue Zazhi, 2023
Boron neutron capture therapy (BNCT) is an advanced radiation therapy technique that is rapidly developing in the field of cancer treatment. This technique, an atomic-level binary targeted therapy, kills cancer cells by causing a 10B(n, α)7Li nuclear ...
LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li   +13 more
doaj   +1 more source

Boron neutron capture therapy induces cell cycle arrest and cell apoptosis of glioma stem/progenitor cells in vitro [PDF]

, 2013
BACKGROUND: Glioma stem cells in the quiescent state are resistant to clinical radiation therapy. An almost inevitable glioma recurrence is due to the persistence of these cells.
Bin Li, Guilin Chen, Jie Wu, Ting Sun, Xueshun Xie, Yongxin Wei, Youxin Zhou, Ziwei Du, Zizhu Zhang   +8 more
core   +1 more source