Results 21 to 30 of about 3,705 (207)

Apoptosis through Bcl-2/Bax and cleaved caspase up-regulation in melanoma treated by boron neutron capture therapy. [PDF]

PLoS ONE, 2013
Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam.
Fernanda Faião-Flores, Paulo Rogério Pinto Coelho, João Dias Toledo Arruda-Neto, Silvya Stuchi Maria-Engler, Manoela Tiago, Vera Luiza Capelozzi, Ricardo Rodrigues Giorgi, Durvanei Augusto Maria   +7 more
doaj   +1 more source

Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy

Nature Communications, 2023
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li ...
Yaxin Shi, Zhibin Guo, Qiang Fu, Xinyuan Shen, Zhongming Zhang, Wenjia Sun, Jinqiang Wang, Junliang Sun, Zizhu Zhang, Tong Liu, Zhen Gu, Zhibo Liu   +11 more
doaj   +1 more source

ASSESSMENT OF THE EFFECT OF BORON NEUTRON CAPTURE THERAPY ON TUMOR CELL LINES AND PRIMARY EMBRYONIC CELL CULTURE

Сибирский онкологический журнал, 2021
Introduction. Boron neutron capture therapy (bnct) is a promising method for treating tumors, in particular, infiltrative malignant tumors, due to the selective destruction of tumor cells without damaging the surrounding normal tissues.
V. V. Kanygin, A. I. Kasatova, I. A. Razumov, E. L. Zavyalov, A. I. Kichigin, R. A. Mukhamadiyarov, S. Yu. Taskaev   +6 more
doaj   +1 more source

Design of a scintillator-based prompt gamma camera for boron-neutron capture therapy: Comparison of SrI2 and GAGG using Monte-Carlo simulation

Nuclear Engineering and Technology, 2021
Boron–neutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutron reactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation is essential for ensuring the accuracy and safety of BNCT. We
Minho Kim, Bong Hwan Hong, Ilsung Cho, Chawon Park, Sun-Hong Min, Won Taek Hwang, Wonho Lee, Kyeong Min Kim   +7 more
doaj   +1 more source

Dose computation for Boron Neutron Capture Therapy (BNCT)

The treatment planning system RayStation currently uses external dose engines for treatment planning of the radiation therapy Boron Neutron Capture Therapy (BNCT), which are relatively slow. The development of fast and accurate dose engines is essential for enabling more effective treatments in cancer care.
Rudengren, Isabella
core   +3 more sources

Biological Distribution in Patients of Boron Agent 4-Borono-L-Phenylalanine for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
Boron neutron capture therapy(BNCT) is a binary targeted radiation therapy in which neutron does not directly provide tumor dose. The dose produced by the 10B(n, α)7Li capture reaction will be deposited in tumor cells by using targeted 10B agents ...
ZHU Xia-yang, LIU Kai, SHAO Yu-jun, JIN Cong-jun, ZHAO Chun-yuan, CHONG Yi-zheng, GUO Zhi-bin, SUN Qi, LIU Zhi-bo, LIU Tong, ZHANG Zi-zhu   +10 more
doaj   +1 more source

“Sequential” Boron Neutron Capture Therapy (BNCT): A Novel Approach to BNCT for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model [PDF]

, 2011
In the present study the therapeutic effect and potential toxicity of the novel "“Sequential"†boron neutron capture therapy (Seq-BNCT) for the treatment of oral cancer was evaluated in the hamster cheek pouch model at the RA-3 Nuclear Reactor.
Itoiz, María Elina, Jorge Quintana, Heber, Elisa Mercedes, Emiliano C. C Pozzi, Ana J Molinari, Elisa M Heber, Marcelo Miller, Quintana, Jorge, Trivillin, Verónica Andrea, Molinari, Ana Julia, Thorp, Silvia Inés, Romina F Aromando, Verónica A Trivillin, Gustavo A Santa Cruz, Marcela A Garabalino, Andrea Monti Hughes, Miller, Marcelo, Amanda E Schwint, Nigg, David W., David W Nigg, Santa Cruz, Gustavo Alberto, Monti Hughes, Andrea, Garabalino, Marcela Alejandra, Pozzi, Emiliano César Cayetano, Schwint, Amanda Elena, Maria E Itoiz, Aromando, Romina F., Silvia I Thorp   +27 more
core   +1 more source

Synthesis of a Boronated Naphthalimide for Potential Use in Boron Neutron Capture Therapy (BNCT). [PDF]

Acta Chemica Scandinavica, 1999
Synthesis of a boronated naphthalimide for potential use in boron neutron capture therapy (BNCT)
Hadi Ghaneolhosseini, Stefan Sjöberg, Mona Kvivesen, Leif J. Sæthre, Markku Ahlgrén, Jouni Pursiainen, Hong-Gen Wang, Xin-Kan Yao, Hong-Gen Wang, J. -P. Tuchagues, Mattias Ögren   +10 more
openaire   +2 more sources

The Role of BNCT in Breast Cancer Treatment

Atom Indonesia, 2019
Boron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer ...
B. Poedjomartono, Y. Sardjono, E. Meiyanto, H. Winarno   +3 more
doaj   +1 more source

Principles and Clinical Applications of Boron Neutron Capture Therapy

Xiehe Yixue Zazhi, 2023
Boron neutron capture therapy (BNCT) is an advanced radiation therapy technique that is rapidly developing in the field of cancer treatment. This technique, an atomic-level binary targeted therapy, kills cancer cells by causing a 10B(n, α)7Li nuclear ...
LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li   +13 more
doaj   +1 more source