Results 21 to 30 of about 3,740,560 (195)

Optimising neutron production from compact low energy accelerators [PDF]

, 2012
There is currently much development in accelerator based methods to provide flexible and reliable neutron generators, in response to a decline in the availability of nuclear reactors.
Cywinski, Robert, Bungau, Adriana, Edgecock, R., Ratcliffe, N, Barlow, Roger   +4 more
core   +3 more sources

The basis and advances in clinical application of boron neutron capture therapy

Radiation Oncology, 2021
Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selectively damages cancer cells while sparing ...
Huifang He, Jiyuan Li, Ping Jiang, Suqing Tian, Hao Wang, Ruitai Fan, Junqi Liu, Yuyan Yang, Zhibo Liu, Junjie Wang   +9 more
doaj   +1 more source

Experimental study on Compton camera for boron neutron capture therapy applications

Scientific Reports, 2023
Boron neutron capture therapy (BNCT) is a high-dose-intensive radiation therapy that has gained popularity due to advancements in accelerator neutron sources.
M. Sakai, S. Tamaki, I. Murata, R. K. Parajuli, A. Matsumura, N. Kubo, M. Tashiro   +6 more
doaj   +1 more source

Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation

Cells, 2021
Background: Boron neutron capture therapy (BNCT) is a nuclear reaction-based tumor cell-selective particle irradiation method. High-dose methotrexate and whole-brain radiation therapy (WBRT) are the recommended treatments for primary central nervous ...
Kohei Yoshimura, Shinji Kawabata, Hideki Kashiwagi, Yusuke Fukuo, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Tsubasa Watanabe, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Masahiko Wanibuchi   +13 more
doaj   +1 more source

Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy

Nature Communications, 2023
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that may selectively deposit two deadly high-energy particles (4He and 7Li ...
Yaxin Shi, Zhibin Guo, Qiang Fu, Xinyuan Shen, Zhongming Zhang, Wenjia Sun, Jinqiang Wang, Junliang Sun, Zizhu Zhang, Tong Liu, Zhen Gu, Zhibo Liu   +11 more
doaj   +1 more source

Apoptosis through Bcl-2/Bax and cleaved caspase up-regulation in melanoma treated by boron neutron capture therapy. [PDF]

PLoS ONE, 2013
Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam.
Fernanda Faião-Flores, Paulo Rogério Pinto Coelho, João Dias Toledo Arruda-Neto, Silvya Stuchi Maria-Engler, Manoela Tiago, Vera Luiza Capelozzi, Ricardo Rodrigues Giorgi, Durvanei Augusto Maria   +7 more
doaj   +1 more source

ASSESSMENT OF THE EFFECT OF BORON NEUTRON CAPTURE THERAPY ON TUMOR CELL LINES AND PRIMARY EMBRYONIC CELL CULTURE

Сибирский онкологический журнал, 2021
Introduction. Boron neutron capture therapy (bnct) is a promising method for treating tumors, in particular, infiltrative malignant tumors, due to the selective destruction of tumor cells without damaging the surrounding normal tissues.
V. V. Kanygin, A. I. Kasatova, I. A. Razumov, E. L. Zavyalov, A. I. Kichigin, R. A. Mukhamadiyarov, S. Yu. Taskaev   +6 more
doaj   +1 more source

Design of a scintillator-based prompt gamma camera for boron-neutron capture therapy: Comparison of SrI2 and GAGG using Monte-Carlo simulation

Nuclear Engineering and Technology, 2021
Boron–neutron capture therapy (BNCT) is a cancer treatment method that exploits the high neutron reactivity of boron. Monitoring the prompt gamma rays (PGs) produced during neutron irradiation is essential for ensuring the accuracy and safety of BNCT. We
Minho Kim, Bong Hwan Hong, Ilsung Cho, Chawon Park, Sun-Hong Min, Won Taek Hwang, Wonho Lee, Kyeong Min Kim   +7 more
doaj   +1 more source

Biological Distribution in Patients of Boron Agent 4-Borono-L-Phenylalanine for Boron Neutron Capture Therapy

He huaxue yu fangshe huaxue, 2023
Boron neutron capture therapy(BNCT) is a binary targeted radiation therapy in which neutron does not directly provide tumor dose. The dose produced by the 10B(n, α)7Li capture reaction will be deposited in tumor cells by using targeted 10B agents ...
ZHU Xia-yang, LIU Kai, SHAO Yu-jun, JIN Cong-jun, ZHAO Chun-yuan, CHONG Yi-zheng, GUO Zhi-bin, SUN Qi, LIU Zhi-bo, LIU Tong, ZHANG Zi-zhu   +10 more
doaj   +1 more source

Principles and Clinical Applications of Boron Neutron Capture Therapy

Xiehe Yixue Zazhi, 2023
Boron neutron capture therapy (BNCT) is an advanced radiation therapy technique that is rapidly developing in the field of cancer treatment. This technique, an atomic-level binary targeted therapy, kills cancer cells by causing a 10B(n, α)7Li nuclear ...
LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li   +13 more
doaj   +1 more source