Results 51 to 60 of about 5,770 (216)

Assesment of Boron Neutron Capture Therapy (BNCT): Compact Neutron Generators

, 2018
Boron  Neutron Capture Therapy (BNCT)  is an effective and promising treatment          of tumour types which are resistant to conventional therapies.
Sardjono, Yohannes, Wahyuni, Nur Setyo
core   +1 more source

Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation

Cells, 2021
Background: Boron neutron capture therapy (BNCT) is a nuclear reaction-based tumor cell-selective particle irradiation method. High-dose methotrexate and whole-brain radiation therapy (WBRT) are the recommended treatments for primary central nervous ...
Kohei Yoshimura, Shinji Kawabata, Hideki Kashiwagi, Yusuke Fukuo, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Tsubasa Watanabe, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Masahiko Wanibuchi   +13 more
doaj   +1 more source

o‐Carborane‐based multi‐resonance thermally activated delayed fluorescence emitter exhibits highly efficient and multifunctional electroluminescence

FlexMat, EarlyView.
By strategically incorporating boron/nitrogen multi‐resonance (B/N‐MR) core into the o‐carborane unit, perfect exciton utilization can be achieved as well as exhibiting stimuli‐responsive properties. The resulting DBN‐oCb‐based organic light‐emitting diode (OLED) demonstrated an impressive external quantum efficiency of 22.3%, the highest reported for ...
Jiasen Zhang, Denghui Liu, Mengke Li, Tong Wang, Yuanyuan Meng, Deli Li, Shi‐Jian Su, Wei Li, Ziyi Ge   +8 more
wiley   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

10B Concentration, Phantom Size and Tumor Location Dependent Dose Enhancement and Neutron Spectra in Boron Neutron Capture Therapy [PDF]

Journal of Biomedical Physics and Engineering, 2019
Background: The amount of average dose enhancement in tumor loaded with 10B may vary due to various factors in boron neutron capture therapy.Objective: This study aims to evaluate dose enhancement in tumor loaded with 10B under influence of various ...
Gh Izadi Vasafi, M M Firoozabadi
doaj   +1 more source

Acral cutaneous malignant melanoma treated with linear accelerator-based boron neutron capture therapy system: a case report of first patient

Frontiers in Oncology, 2023
This study reports the first patient treatment for cutaneous malignant melanoma using a linear accelerator-based boron neutron capture therapy (BNCT) system.
Hiroshi Igaki, Hiroshi Igaki, Satoshi Nakamura, Satoshi Nakamura, Satoshi Nakamura, Naoya Yamazaki, Tomoya Kaneda, Mihiro Takemori, Mihiro Takemori, Tairo Kashihara, Tairo Kashihara, Naoya Murakami, Naoya Murakami, Kenjiro Namikawa, Tetsu Nakaichi, Hiroyuki Okamoto, Kotaro Iijima, Kotaro Iijima, Takahito Chiba, Takahito Chiba, Hiroki Nakayama, Hiroki Nakayama, Ayaka Nagao, Madoka Sakuramachi, Kana Takahashi, Koji Inaba, Kae Okuma, Yuko Nakayama, Kazuaki Shimada, Hitoshi Nakagama, Jun Itami, Jun Itami   +31 more
doaj   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Liver metastases in "Neutron Capture Therapy: Principles and Appliations"

, 2012
Neutron capture therapy (NCT) is based on the ability of the non-radioactive isotope boron-10 to capture thermal neutrons with very high probability and immediately to release heavy particles with a path length of one cell diameter, which in principle ...
ALTIERI, SAVERIO, L. Roveda, ZONTA, ARIS
core   +1 more source

7. Neutron Capture Therapy [PDF]

, 2022
In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2021/ProgRep2021.htmlCO7-1 Synthesis and evaluation of a novel boron neutron capture therapy agent/ H. Kimura and M.

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