Results 61 to 70 of about 5,770 (216)

Transporter‐Associated Therapeutic Efficacy of an SMVT‐Targeted Boron Carrier in Boron Neutron Capture Therapy

Cancer Science, EarlyView.
The transporter‐associated BNCT strategy using BBCIP with or without BPA according to tumor transporter characteristics. BPA showed greater efficacy in LAT1‐dominant F98 glioma, whereas BBCIP was more effective in SMVT‐high CRL1666 tumors, suggesting the potential utility of transporter‐based boron carrier selection in BNCT.
Kenichiro Eza, Kohei Tsujino, Rina Shidoh‐Kazuki, Yoshiki Fujikawa, Hideki Kashiwagi, Gen Futamura, Ryo Hiramatsu, Toshihiro Takami, Masahiko Wanibuchi, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Kai Nishimura, Shota Tanaka, Hiroyuki Nakamura, Shinji Kawabata   +15 more
wiley   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

Immunology &Cell Biology, EarlyView.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari, Farah Ahmady‐Nield, Amit Sharma, Ingo G. H. Schmidt‐Wolf, Jarek Maciaczyk, Rodney B. Luwor, Adrian A. Achuthan   +6 more
wiley   +1 more source

Research on the Design of the BNCT Neutron Beam Device Based on the New Pool-Type Research Reactor

Journal of Isotopes
Based on the design scheme of a new-type swimming pool research reactor，this paper conducts preliminary design for a variable-energy neutron beam facility for boron neutron capture therapy (BNCT).
Song LIANG, Xiaoliang CHEN, Yajie ZUO, Jianping XU   +3 more
doaj   +1 more source

Optimising neutron production from compact low energy accelerators

, 2012
There is currently much development in accelerator based methods to provide flexible and reliable neutron generators, in response to a decline in the availability of nuclear reactors.
Cywinski, Robert, Bungau, Adriana, Edgecock, R., Ratcliffe, N, Barlow, Roger, Bungau, A., Ratcliffe, N., Edgecock, T. R., Barlow, R.   +8 more
core  

A new perspective on radiotherapy in the comprehensive treatment of cancer

Precision Radiation Oncology, Volume 10, Issue 2, Page 165-183, June 2026.
Radiotherapy remains a key component in the comprehensive management of cancer. Its effectiveness is significantly improved through strategic combinations with chemotherapy, targeted therapy, and immunotherapy, providing a range of therapeutic outcomes from cure to palliative care.
Yingze Ma, Hongxuan Yu, Shijie Shang, Shixin Shan, Dawei Chen   +4 more
wiley   +1 more source

Project 1 The effect of boron neutron capture therapy on normal tissues (R3P1) [PDF]

, 2022
In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2021/ProgRep2021.htmlPR1-1 The effect of boron neutron capture therapy (BNCT) on normal lung in mice/ M. Suzuki and
Suzuki, M.
core  

Boron neutron capture therapy and environmental health

Почвознание, агрохимия и екология
Boron Neutron Capture Therapy (BNCT) is an innovative cancer treatment modality that exploits neutron beams to specifically destroy malignant cells.
Sachindra Lochana, Sachini Hettiara
doaj   +1 more source

The Role of BNCT in Breast Cancer Treatment

Atom Indonesia, 2019
Boron neutron capture therapy (BNCT) is a promising future technique of breast cancer therapy. BNCT is a cell-targetting therapy. In BNCT, the use of boron-10 combined with curcumin analog will provide selective radiation therapy only to breast cancer ...
B. Poedjomartono, Y. Sardjono, E. Meiyanto, H. Winarno   +3 more
doaj   +1 more source

Low energy fusion for a safe and compact neutron source

, 2013
Neutrons are primarily produced at large international facilities using either spallation reactions or nuclear fission. There is a demand for small scale neutron production for use at hospitals and borders for a variety of applications.
Seviour, Rebecca, Albright, S.
core  

Development of thermal neutron moderator for testing boron agents for Boron Neutron Capture Therapy (BNCT)

, 2019
We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan ...
999429, Ichikawa, G., Ogawara, Ryo, 999427, 999428, Suda, Mitsuru, Ishikawa, A., Tsuyoshi, Hamano, Ryo, Ogawara, 999430, 999431, Watanabe, K., Kiyanagi, Y., 999418, 999419, 999417, Tsuchida, K., Yoshihashi, S., Igawa, K., Hamano, Tsuyoshi, 999421, 999422, Mitsuru, Suda, 999420, 999425, 999426, 999423, Uritani, A., Hirata, Y., 999424   +29 more
core   +1 more source