Results 51 to 60 of about 2,179 (173)

CYTOPATHIC EFFECTS OF ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY ON HUMAN GLIOBLASTOMA CELLS

Сибирский онкологический журнал, 2019
Boron neutron capture therapy (BNCT) is a targeted therapy based on a selective damage to cancer cells due to the interaction between boron-10 isotope and neutron.
V. A. Byvaltsev, E. L. Zavjalov, V. V. Kanygin, A. I. Kasatova, A. I. Kichigin, I. A. Razumov, T. V. Sycheva, S. Yu. Taskaev   +7 more
doaj   +1 more source

Nanoparticle‐Mediated Therapy for Glioma: Advances and Prospects

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Various nanocarriers, including liposomes, dendrimers, exosomes and gold nanoparticles, are designed to penetrate the blood‐brain barrier and deliver chemotherapy, radiotherapy, immunotherapy, gene therapy, phototherapy, magnetic hyperthermia and sonodynamic therapy for glioma.
Wenqian Jiang, Jing Fei, Rangrang Fan, Haifeng Chen, Liangxue Zhou, Gang Guo   +5 more
wiley   +1 more source

BNCT-RTPE: BNCT radiation treatment planning environment

, 1995
Several improvements have been developed for the BNCT radiation treatment planning environment (BNCT-Rtpe) during 1994. These improvements have been incorporated into Version 1.0 of BNCT-Rtpe which is currently installed at the INEL, BNL, Japanese Research Center (JRC), and Finland`s Technical Research Center.
D E Wessol, F J Wheeler, R S Babcock
openaire   +2 more sources

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

Immunology &Cell Biology, Volume 104, Issue 7, Page 711-728, August 2026.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari, Farah Ahmady‐Nield, Amit Sharma, Ingo G. H. Schmidt‐Wolf, Jarek Maciaczyk, Rodney B. Luwor, Adrian A. Achuthan   +6 more
wiley   +1 more source

Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses

Journal of Hepatocellular Carcinoma, 2022
Chu-Yu Huang,1– 3 Zih-Yin Lai,1– 3 Tzu-Jung Hsu,1– 3 Fong-In Chou,3 Hong-Ming Liu,3 Yung-Jen Chuang1– 3 1School of Medicine, National Tsing Hua University, Hsinchu, Taiwan; 2Institute of Bioinformatics and Structural Biology, National Tsing Hua ...
Huang CY, Lai ZY, Hsu TJ, Chou FI, Liu HM, Chuang YJ   +5 more
doaj  

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, Volume 13, Issue 39, 13 July 2026.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Organocatalytic B–H Functionalization of Carboranes via Photo‐Induced Hydrogen Atom Transfer

ChemistryEurope, Volume 4, Issue 7, July 2026.
Visible‐light organocatalytic hydrogen atom transfer enables direct carborane B─H bond functionalization. A photocatalytically generated cationic aminium radical selectively abstracts hydrogen from hydridic boron sites, forming boron‐centered radicals that couple with activated olefins or imines to deliver B‐functionalized carboranes under mild ...
Takaya Sakaue, Kana Yasuda, Tsukasa Tawatari, Akira Matsumoto, Keiichi Hirano, Kiyosei Takasu, Hiroshi Takikawa   +6 more
wiley   +1 more source

Principles of Biocompatible Nanotube Design for High‐Performance Biomaterials

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 4, July/August 2026.
Schematic overview of nanotube‐based biomaterials for biomedical applications. ABSTRACT Nanotubes are one‐dimensional tubular structures characterized by nanoscale radial dimensions and micrometer‐scale axial lengths. Their hollow inner cavity confers a high specific surface area and distinctive physicochemical properties, enabling remarkable potential
Yue Zhong, José A. Lebrón, María L. Moyá, Manuel López‐López, Francisco J. Ostos, Pilar López‐Cornejo   +5 more
wiley   +1 more source

PRELIMINARY MATHEMATICAL MODEL FOR CANCER TREATMENT USING BORON NEUTRON CANCER THERAPY (BNCT)

Barekeng
This article outlines a revolutionary approach to immunotherapy and stem-cell cancer treatments that leverages Boron Neutron Cancer Therapy (BNCT). We formulated two models, one being the immunotherapy-BNCT model and the other featuring a stem-cell ...
Suryasatriya Trihandaru, Hanna Arini Parhusip, Yohannes Sardjono, Isman Mulyadi Triatmoko, Gede Sutresna Wijaya, Jane Labadin   +5 more
doaj   +1 more source

Boron neutron capture therapy for melanoma: recent advances and future prospects

Frontiers in Oncology
Boron neutron capture therapy (BNCT) is a unique radiotherapy modality that targets and destroys selectively tumor cells that have absorbed boron, while leaving surrounding healthy cells unharmed.
Yuanyang Sun, Yun Wang, Shukun Mu, Xiaofeng Wu, Suchun Yu, Zhongming Wang   +5 more
doaj   +1 more source