Results 51 to 60 of about 2,170 (170)

The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications

open access: yesAngewandte Chemie, Volume 138, Issue 20, 11 May 2026.
This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec   +10 more
wiley   +2 more sources

Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses

open access: yesJournal of Hepatocellular Carcinoma, 2022
Chu-Yu Huang,1– 3 Zih-Yin Lai,1– 3 Tzu-Jung Hsu,1– 3 Fong-In Chou,3 Hong-Ming Liu,3 Yung-Jen Chuang1– 3 1School of Medicine, National Tsing Hua University, Hsinchu, Taiwan; 2Institute of Bioinformatics and Structural Biology, National Tsing Hua ...
Huang CY   +5 more
doaj  

Development of Measuring 10B Concentrations in Boron Neutron Capture Therapy

open access: yesHe huaxue yu fangshe huaxue, 2023
Boron neutron capture therapy(BNCT), as a highly promising radiotherapy modality, has emerged as a significant treatment option for various malignant tumors, including high-grade gliomas, recurrent head and neck cancers, and melanoma.
LI Lin   +3 more
doaj   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

open access: yesSmall, EarlyView.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem   +12 more
wiley   +1 more source

Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series

open access: yesLife, 2022
Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem
Yi-Wei Chen   +31 more
doaj   +1 more source

BNCT-RTPE: BNCT radiation treatment planning environment

open access: yes, 1995
Several improvements have been developed for the BNCT radiation treatment planning environment (BNCT-Rtpe) during 1994. These improvements have been incorporated into Version 1.0 of BNCT-Rtpe which is currently installed at the INEL, BNL, Japanese Research Center (JRC), and Finland`s Technical Research Center.
D E Wessol, F J Wheeler, R S Babcock
openaire   +2 more sources

Transporter‐Associated Therapeutic Efficacy of an SMVT‐Targeted Boron Carrier in Boron Neutron Capture Therapy

open access: yesCancer Science, EarlyView.
The transporter‐associated BNCT strategy using BBCIP with or without BPA according to tumor transporter characteristics. BPA showed greater efficacy in LAT1‐dominant F98 glioma, whereas BBCIP was more effective in SMVT‐high CRL1666 tumors, suggesting the potential utility of transporter‐based boron carrier selection in BNCT.
Kenichiro Eza   +15 more
wiley   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

open access: yesImmunology &Cell Biology, EarlyView.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari   +6 more
wiley   +1 more source

Organocatalytic B–H Functionalization of Carboranes via Photo‐Induced Hydrogen Atom Transfer

open access: yesChemistryEurope, Volume 4, Issue 7, July 2026.
Visible‐light organocatalytic hydrogen atom transfer enables direct carborane B─H bond functionalization. A photocatalytically generated cationic aminium radical selectively abstracts hydrogen from hydridic boron sites, forming boron‐centered radicals that couple with activated olefins or imines to deliver B‐functionalized carboranes under mild ...
Takaya Sakaue   +6 more
wiley   +1 more source

Blue‐hazard‐free single‐emissive‐layer white organic LEDs based on an anti‐quenching narrowband blue emitter

open access: yesFlexMat, Volume 3, Issue 2, Page 219-227, June 2026.
A blue‐hazard‐free single‐emissive‐layer white OLED is realized using an anti‐quenching multiple‐resonance TADF emitter, BNCT. By integrating a sterically protected MR core with efficient energy transfer capability, BNCT enables warm‐white emission with high efficiency, negligible hazardous blue photons, and a simplified device architecture for next ...
Xiao‐Long Liu   +9 more
wiley   +1 more source

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