Results 51 to 60 of about 6,494 (198)

A Boronated Derivative of Temozolomide Showing Enhanced Efficacy in Boron Neutron Capture Therapy of Glioblastoma

open access: yesCells, 2022
There is an incontestable need for improved treatment modality for glioblastoma due to its extraordinary resistance to traditional chemoradiation therapy. Boron neutron capture therapy (BNCT) may play a role in the future.
Jing Xiang   +9 more
doaj   +1 more source

Genetics and genomics of BNCT among basics and perspectives [PDF]

open access: yes, 2017
The Boron neutron capture therapy (BNCT) bases its therapeutic action on the selective ability to induce DNA damage of tumor cells with the aim to cause their death by apoptosis or necrosis, preserving as much as possible the normal cells.
CARADONNA, Fabio
core  

BNCT dosimetry: peculiarities and methods [PDF]

open access: yes, 2019
Dosimetry in tissue exposed to the epithermal neutron beams utilized for BNCT is complex, due to the multiplicity of the possible neutron reactions and consequently of the secondary radiation that contains photons, charged particles and recoil nuclei ...
D Bettega   +7 more
core   +1 more source

CYTOPATHIC EFFECTS OF ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY ON HUMAN GLIOBLASTOMA CELLS

open access: yesСибирский онкологический журнал, 2019
Boron neutron capture therapy (BNCT) is a targeted therapy based on a selective damage to cancer cells due to the interaction between boron-10 isotope and neutron.
V. A. Byvaltsev   +7 more
doaj   +1 more source

Synthesis and Functional Properties of Fluorinated Phosphonate‐Substituted Porphyrins: Excellent Photosensitizers and Robust Precursors for Photoactive Langmuir–Schaefer Films

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
This is a comprehensive study of new family of high functionalized meso‐tetraarylporphyrins. A synthetic approach to phosphonate‐substituted fluorinated porphyrins was developed. These compounds were investigated with respect to singlet oxygen generation and photostability.
Azhar Kechiche   +8 more
wiley   +1 more source

Parameters of the BNCT and BNCT+IMRT plans, applied to nine patients.

open access: yes, 2019
Parameters of the BNCT and BNCT+IMRT plans, applied to nine patients.
Yi-Chiao Teng (6555656)   +5 more
core   +1 more source

Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses

open access: yesJournal of Hepatocellular Carcinoma, 2022
Chu-Yu Huang,1– 3 Zih-Yin Lai,1– 3 Tzu-Jung Hsu,1– 3 Fong-In Chou,3 Hong-Ming Liu,3 Yung-Jen Chuang1– 3 1School of Medicine, National Tsing Hua University, Hsinchu, Taiwan; 2Institute of Bioinformatics and Structural Biology, National Tsing Hua ...
Huang CY   +5 more
doaj  

Targeting M-MDSCs enhances the therapeutic effect of BNCT in the 4-NQO-induced murine head and neck squamous cell carcinoma model

open access: yesFrontiers in Oncology, 2023
PurposeMalignant head and neck squamous cell carcinoma (HNSCC) is characterized by a poor prognosis and resistance to conventional radiotherapy. Infiltrating myeloid-derived suppressive cells (MDSCs) is prominent in HNSCC and is linked to immune ...
Chun-Hsiang Chang   +7 more
doaj   +1 more source

BNCT-RTPE: BNCT radiation treatment planning environment

open access: yes, 1995
Several improvements have been developed for the BNCT radiation treatment planning environment (BNCT-Rtpe) during 1994. These improvements have been incorporated into Version 1.0 of BNCT-Rtpe which is currently installed at the INEL, BNL, Japanese Research Center (JRC), and Finland`s Technical Research Center.
D E Wessol, F J Wheeler, R S Babcock
openaire   +2 more sources

Drug Delivery With Metal–Organic Frameworks

open access: yesAngewandte Chemie Novit, Volume 2, Issue 3, September 2026.
Metal–organic frameworks (MOFs) have recently entered human clinical trials for cancer radiotherapy, highlighting both the maturity and potential of MOFs as platforms for drug delivery. This minireview introduces the principles of MOF‐based drug delivery and discusses key opportunities and design challenges that will shape the next generation of these ...
Nathalie W. Tarabay   +6 more
wiley   +1 more source

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