Results 61 to 70 of about 8,497 (207)

Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series

open access: yesLife, 2022
Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem
Yi-Wei Chen   +31 more
doaj   +1 more source

A Study of the Production of Neutrons for Boron Neutron Capture Therapy using a Proton Accelerator [PDF]

open access: yes, 2014
Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy particularly well-suited to treating aggressive tumours that exhibit a high degree of infiltration of the surrounding healthy tissue. Such tumours, for example of the brain and lung, provide
Bennett, J.R.J.   +4 more
core  

Prognostic factors in glioblastoma multiforme patients receiving high-dose particle radiotherapy or conventional radiotherapy [PDF]

open access: yes, 2011
The aim of this study was to evaluate the influence of prognostic factors related to patient selection on survival outcomes. Survival outcomes were retrospectively analysed in a consecutive series of 67 newly diagnosed glioblastoma multiforme (GBM ...
Ishikawa E   +12 more
core   +1 more source

INEL BNCT Program [PDF]

open access: yes, 1991
This Bulletin presents a summary of accomplishments and highlights in the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Program for April 1991. This bulletin includes information on the brain tumor and melanoma research programs, Power Burst Facility (PBF) technical support and modifications, PBF operations, a ...
openaire   +2 more sources

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

open access: yesChemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses

open access: yesJournal of Hepatocellular Carcinoma, 2022
Chu-Yu Huang,1– 3 Zih-Yin Lai,1– 3 Tzu-Jung Hsu,1– 3 Fong-In Chou,3 Hong-Ming Liu,3 Yung-Jen Chuang1– 3 1School of Medicine, National Tsing Hua University, Hsinchu, Taiwan; 2Institute of Bioinformatics and Structural Biology, National Tsing Hua ...
Huang CY   +5 more
doaj  

Sviluppo e applicazioni della boron neutron capture therapy [PDF]

open access: yes, 2017
La Boron Neutron Capture Therapy è una tecnica terapeutica altamente selettiva, utilizzata in oncologia, che si basa sulla reazione di cattura neutronica 10B(n,α)7Li .
Guidi, Claretta
core  

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

open access: yesAdvanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova   +15 more
wiley   +1 more source

Improved Boron Neutron Capture Therapy Using Integrin αvβ3-Targeted Long-Retention-Type Boron Carrier in a F98 Rat Glioma Model

open access: yesBiology, 2023
Integrin αvβ3 is more highly expressed in high-grade glioma cells than in normal tissues. In this study, a novel boron-10 carrier containing maleimide-functionalized closo-dodecaborate (MID), serum albumin as a drug delivery system, and cyclic arginine ...
Kohei Tsujino   +18 more
doaj   +1 more source

Taming the Immiscibility of Gold, Iron, and Boron to Craft Chemodegradable Nanoparticles for Multimodal Imaging and Radiotherapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
Over half of cancer patients undergo radiotherapy. Laser ablation enabled the synthesis of immiscible Au‐Fe‐B nanoparticles designed as degradable bimodal radiosensitizers for X‐ray radiotherapy (XRT), boron neutron capture therapy (BNCT), and bimodal imaging for X‐ray computed tomography (CT) and magnetic resonance imaging (MRI). These nanosensitizers
Michael Bissoli   +15 more
wiley   +1 more source

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