Results 71 to 80 of about 2,170 (170)

Development of an integrated Monte Carlo model for glioblastoma multiforme treated with boron neutron capture therapy

Scientific Reports, 2017
Glioblastomas (GBM) are notorious for their high fatality rate. Boron Neutron Capture Therapy (BNCT) being a biochemically targeted type of radiotherapy is a potent modality for GBM.
Leyla Moghaddasi, Eva Bezak
doaj   +1 more source

Comparison of lifetime attributable risk of post-irradiation secondary cancer of boron neutron capture therapy, proton beam therapy, and X-ray therapy for pediatric and adolescent and young adult patients

Clinical and Translational Radiation Oncology
Background and purpose: This study aimed to compare the post-irradiation secondary cancer rates of boron neutron capture therapy (BNCT), proton beam therapy (PBT), and X-ray therapy (XT) in pediatric and Adolescent and Young Adult (AYA) patients with ...
Shunsuke Suzuki, Shintaro Shiba, Hiroki Tanaka, Masashi Yamanaka, Kazuki Matsumoto, Koichi Tokuuye, Motoko Omura   +6 more
doaj   +1 more source

Clinical requirements and accelerator concepts for BNCT

Proceedings of the 1997 Particle Accelerator Conference (Cat. No.97CH36167), 2002
Accelerator-based neutron sources are an attractive alternative to nuclear reactors for providing epithermal neutron beams for boron neutron capture therapy. Based on clinical requirements and neutronics modeling the use of proton and deuteron induced reactions in /sup 7/Li and /sup 9/Be targets has been compared. Excellent epithermal neutron beams can
openaire   +2 more sources

Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance

Oncogenesis
Squamous cell carcinoma (SCC) poses a significant global health challenge due to the lack of effective treatments. Boron neutron capture therapy (BNCT), a targeted particle therapy, has shown promising results in various cancers. SLC7A5, a transporter of
Yen-Ju Lin, Yu-Cheng Wu, Yu-Jui Liu, Wei-Chen Yeh, Yi-Chen Huang, Shen-Ao Zhang, Alvin Chen, Ming-Yi Zheng, Hong-Ming Liu, Fong-In Chou, Shien-Tung Pan, Min-Yuan Chou, Yu-Ting Chou   +12 more
doaj   +1 more source

Antibody-Based Receptor Targeting Using an Fc-Binding Peptide-Dodecaborate Conjugate and Macropinocytosis Induction for Boron Neutron Capture Therapy

ACS Omega, 2020
Ikuhiko Nakase, Ayako Aoki, Yuriko Sakai, Shiori Hirase, Miki Ishimura, Tomoka Takatani-Nakase, Yoshihide Hattori, Mitsunori Kirihata   +7 more
doaj   +1 more source

Microdosimetria in BNCT

La terapia per la cattura neutronica del boro (BNCT) è una forma avanzata di radioterapia sperimentale, per trattare tumori aggressivi e infiltranti quali il glioblastoma. La tecnica consiste nella somministrazione di un farmaco che veicola selettivamente all’interno delle cellule neoplastiche un isotopo del boro non radioattivo, il Boro-10, e il ...
openaire   +1 more source

Potential targets for boron transport in boron neutron capture therapy. [PDF]

Front Oncol
Wei Y, Zhu W, Chen Q, Alnufaei H, Li Y, Ricketts K.   +5 more
europepmc   +1 more source

Integrating measurement and simulation for evaluation of patient-specific whole-body dosimetry in clinical BNCT. [PDF]

Med Phys
Kakino R, Hu N, Sasaki A, Nojiri M, Yoshino Y, Takeno S, Aihara T, Matsubayashi N, Takata T, Tanaka H, Nihei K, Ono K.   +11 more
europepmc   +1 more source

The boron uptake via LAT1 and survival analysis after boron neutron capture therapy in canine hemangiosarcoma cell lines. [PDF]

Front Vet Sci
Iwasaki R, Uchida S, Yoshikawa R, Yoshihashi S, Suzuki M, Mori T.   +5 more
europepmc   +1 more source

An Outline of BNCT and Switchover to Accelerator Based BNCT System

RADIOISOTOPES, 2015
openaire   +2 more sources