Results 181 to 190 of about 15,146 (248)

Stereoselective Synthesis of β‐C‐glycosides From Exoglycals Through Radical C─C Bond Formation

open access: yesChemistry – A European Journal, EarlyView.
We describe herein a convenient strategy for the preparation of β‐C‐glycosides via the addition of radical species onto exoglycals. This method is efficient, general and achieved in mild conditions starting from xanthates derivatives and using triethylborane as initiator and 4‐tert‐butylcatechol as hydrogen atom source. This hydroalkylation reaction is
Noémie Murard   +2 more
wiley   +1 more source

Partially Biobased Polyurethanes With Reversibly Crosslinkable Furan Units Toward Recyclable Thermosetting Textile Fibres

open access: yesChemistry – A European Journal, EarlyView.
A molecular design strategy combines lignin‐derived aromatic units, sugar‐derived furan groups, and flexible glycol segments to create wet‐spinnable polyurethanes. Thermally reversible Diels–Alder crosslinking chemistry enables formation of crosslinked thermosetting fibers, repeated de‐crosslinking/re‐crosslinking cycles, and tunable fiber properties ...
Rafael N. L. Menezes   +7 more
wiley   +1 more source

Illuminating Olympicenes: Insights Into Anti‐Kasha Photophysics in Polycyclic Aromatic Hydrocarbons

open access: yesChemistry – A European Journal, EarlyView.
Compact olympicene‐based chromophores reveal unexpectedly rich excited‐state behavior, including dual fluorescence, excitation‐dependent emission, and anti‐Kasha‐type emission. Tunable locally excited and intramolecular charge‐transfer states emerge from subtle structural changes, expanding the design rules for polycyclic aromatic chromophores and ...
Wenlong Li   +5 more
wiley   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

How to Optimize Healthy Volunteer Screening and Enrolment in Clinical Trials: A Qualitative and Quantitative Approach to Evaluate Processes and Healthy Volunteers' Perceptions

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer   +10 more
wiley   +1 more source

Engineering Cobalt Bis(dicarbollide)-Loaded Polymeric Nanocarriers: From Controlled Fabrication to Drug Delivery for BNCT. [PDF]

open access: yesJ Funct Biomater
Klimenko MA   +15 more
europepmc   +1 more source

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