Stereoselective Synthesis of β‐C‐glycosides From Exoglycals Through Radical C─C Bond Formation
We describe herein a convenient strategy for the preparation of β‐C‐glycosides via the addition of radical species onto exoglycals. This method is efficient, general and achieved in mild conditions starting from xanthates derivatives and using triethylborane as initiator and 4‐tert‐butylcatechol as hydrogen atom source. This hydroalkylation reaction is
Noémie Murard +2 more
wiley +1 more source
A Porphyrinic Covalent Organic Polymer Nanoplatform for Carborane Delivery and Multifunctional Imaging-Guided Boron Neutron Capture Therapy of Breast Cancer. [PDF]
Ren J, Wang T, Zuo C, Zhang R, Li L.
europepmc +1 more source
A molecular design strategy combines lignin‐derived aromatic units, sugar‐derived furan groups, and flexible glycol segments to create wet‐spinnable polyurethanes. Thermally reversible Diels–Alder crosslinking chemistry enables formation of crosslinked thermosetting fibers, repeated de‐crosslinking/re‐crosslinking cycles, and tunable fiber properties ...
Rafael N. L. Menezes +7 more
wiley +1 more source
Bystander and abscopal effects of boron neutron capture therapy: radiobiological mechanisms and immunotherapeutic strategies. [PDF]
Zhang Z +5 more
europepmc +1 more source
Illuminating Olympicenes: Insights Into Anti‐Kasha Photophysics in Polycyclic Aromatic Hydrocarbons
Compact olympicene‐based chromophores reveal unexpectedly rich excited‐state behavior, including dual fluorescence, excitation‐dependent emission, and anti‐Kasha‐type emission. Tunable locally excited and intramolecular charge‐transfer states emerge from subtle structural changes, expanding the design rules for polycyclic aromatic chromophores and ...
Wenlong Li +5 more
wiley +1 more source
Small-Molecule Boron-10-Enriched Carriers with Exceptional Aqueous Solubility for Enhanced Boron Neutron Capture Therapy of Malignant Tumors. [PDF]
Xiong T +8 more
europepmc +1 more source
C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens +3 more
wiley +1 more source
<i>Hj</i>-aggregates of quinoline-fused boron-dipyrromethene nanoparticles for near-infrared dualmodal photodynamic and photothermal therapy. [PDF]
Zhang B +6 more
europepmc +1 more source
Healthy volunteers (HVs) are essential for phase I trials, yet their recruitment and screening remain resource‐intensive and ethically complex. High screening failure (SF) rates highlight the need to evaluate and understand all aspects of the enrolment processes. We analyzed SF patterns in a large German HV cohort and explored participants' motivations,
Evelyn Krohmer +10 more
wiley +1 more source
Engineering Cobalt Bis(dicarbollide)-Loaded Polymeric Nanocarriers: From Controlled Fabrication to Drug Delivery for BNCT. [PDF]
Klimenko MA +15 more
europepmc +1 more source

