Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Introduction Ticks (Acari: Ixodida) are vectors and/or reservoirs of many pathogens, i.e. Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti .
Marek Asman +4 more
doaj +1 more source
Identification of Borrelia species after creation of an in-house MALDI-TOF MS database.
Lyme borreliosis (LB) is a multisystemic disease caused by Borrelia burgdorferi sensu lato (sl) complex transmitted to humans by Ixodes ticks. B. burgdorferi sl complex, currently comprising at least 19 genospecies, includes the main pathogenic species ...
Adriana Calderaro +10 more
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Bacteria of the Borrelia burgdorferi sensu lato complex are the causative agents of Lyme borreliosis (LB). Even if the conventional diagnosis of LB does not rely on the species itself, an accurate species identification within the complex will provide a ...
Giulia Chiappa +11 more
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Since its recent discovery in the late 1970s, Lyme Disease (LD) has been a growing public health concern, especially in the United States where it accounts for the majority of vector-borne infections each year. The causative agent, Borrelia burgdorferi, is transmitted to humans through the bite of an infected Ixodes tick. This pathogen uses many unique
Andrew Gaetano, Elizabeth Danka
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Genotypic variation and mixtures of Lyme Borrelia in Ixodes ticks from North America and Europe. [PDF]
Lyme disease, caused by various species of Borrelia, is transmitted by Ixodes ticks in North America and Europe. Studies have shown the genotype of Borrelia burgdorferi sensu stricto (s.s.) or the species of B.
Chris D Crowder +11 more
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Modeling the effects of variable feeding patterns of larval ticks on the transmission of Borrelia lusitaniae and Borrelia afzelii [PDF]
Spirochetes belonging to the Borrelia burgdoferi sensu lato (sl) group cause Lyme Borreliosis (LB), which is the most commonly reported vector-borne zoonosis in Europe. B. burgdorferi sl is maintained in nature in a complex cycle involving Ixodes ricinus
Bertolotti, Luigi +5 more
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The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer +76 more
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Lyme Disease—An Unusual Cause of a Mitral Valve Endocarditis
Lyme disease is a tick-borne infection caused by Borrelia burgdorferi. Cardiac manifestations are rare, occurring in 0.5% to 10% of patients. Lyme carditis and atrioventricular block are established manifestations of Lyme disease.
Benish Fatima, MD +2 more
doaj +1 more source
Diagnostic value of PCR analysis of synovial fluid for the diagnosis of Lyme borreliosis in dogs [PDF]
Lyme borreliosis, also known as Lyme disease, is a chronic multiorgan disease of humans and animals transmitted by ticks of the Ixodidae family and caused by a group of spirochetes Borrelia burgdorferi sensu lato.
Panteleienko O., Tsarenko T.
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