The urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferi. [PDF]
The causative agent of Lyme borreliosis, the spirochete Borrelia burgdorferi, has been shown to induce expression of the urokinase receptor (uPAR); however, the role of uPAR in the immune response against Borrelia has never been investigated.
Joppe W R Hovius+15 more
doaj +1 more source
Statistical analysis of the distribution of amino acids in Borrelia burgdorferi genome under different genetic codes [PDF]
The genetic code is considered to be universal. In order to test if some statistical properties of the coding bacterial genome were due to inherent properties of the genetic code, we compared the autocorrelation function, the scaling properties and the maximum entropy of the distribution of distances of amino acids in sequences obtained by translating ...
arxiv +1 more source
The role of Borrelia burgdorferi infection in scleroderma
Borrelia burgdorferi , a Gram-negative, spiral-shaped bacterium transmitted to humans via tick bites, is the etiologic agent of borreliosis (Lyme disease) with diverse clinical manifestations. There are several types of pathological lesions in the course
Żaneta Smoleńska+3 more
doaj +1 more source
A Large Scale Spatio-temporal Binomial Regression Model for Estimating Seroprevalence Trends [PDF]
This paper develops a large-scale Bayesian spatio-temporal binomial regression model for the purpose of investigating regional trends in antibody prevalence to Borrelia burgdorferi, the causative agent of Lyme disease. The proposed model uses Gaussian predictive processes to estimate the spatially varying trends and a conditional autoregressive model ...
arxiv +1 more source
Borrelia burgdorferi is the causative agent of Lyme disease in the U.S., with at least 25,000 cases reported to the CDC each year. B. burgdorferi is thought to enter and exit the bloodstream to achieve rapid dissemination to distal tissue sites during ...
Jennifer A Caine, J. Coburn
semanticscholar +1 more source
Lyme borreliosis: Epidemiology, clinical manifestations and treatment [PDF]
Lyme borreliosis is a multisystem disorder characterized by a wide spectrum of clinical manifestations. In Europe, the main aetiological agents are Borrelia afzelii, Borrelia garinii and B.
Veinović Gorana+2 more
doaj +1 more source
Detecting Lyme Disease Using Antibody-Functionalized Single-Walled Carbon Nanotube Transistors [PDF]
We examined the potential of antibody-functionalized single-walled carbon nanotube (SWNT) field-effect transistors (FETs) for use as a fast and accurate sensor for a Lyme disease antigen. Biosensors were fabricated on oxidized silicon wafers using chemical vapor deposition grown carbon nanotubes that were functionalized using diazonium salts ...
arxiv +1 more source
Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells
Borrelia burgdorferi is the causative agent of Lyme disease, which affects an estimated 300,000 people annually in the United States. When treated early, the disease usually resolves, but when left untreated, it can result in symptoms such as arthritis ...
Bijaya Sharma+4 more
semanticscholar +1 more source
A case of ocular lesions in a patient with both tick borne borreliosis and toxoplasmosis
Background: The prevalence of tick borne borreliosis has increased significantly in recent years. There have been reports on conjunctivitis, anterior uveitis, optic neuritis and other inflammatory eye diseases caused by Borrelia species.
V. M. Sakovych+3 more
doaj +1 more source
Morphological and biochemical features of Borrelia burgdorferi pleomorphic forms
The spirochaete bacterium Borrelia burgdorferi sensu lato is the causative agent of Lyme disease, the most common tick-borne infection in the northern hemisphere.
Leena Meriläinen+3 more
semanticscholar +1 more source