Results 61 to 70 of about 10,367 (104)

Isochores Merit the Prefix 'Iso'

, 2002
The isochore concept in human genome sequence was challenged in an analysis by the International Human Genome Sequencing Consortium (IHGSC). We argue here that a statement in IGHSC analysis concerning the existence of isochore is incorrect, because it ...
Beck, Bernaola-Galván, Bernardi, Bernardi, Bernardi, Bernardi, Bettecken, Clay, Cuny, Fukagawa, Fukagawa, Jose L Oliver, Lander, Li, Li, Li, Li, Oliver, Pedro Bernaola-Galván, Pedro Carpena, Stephens, Sueoka, Sueoka, Wentian Li   +23 more
core   +3 more sources

Extravasation of Borrelia burgdorferi Across the Blood–Brain Barrier is an Extremely Rare Event

Advanced Science, Volume 12, Issue 17, May 8, 2025.
Lyme disease is caused by vascular dissemination of the bacteria Borrelia. In a 3D tissue‐engineered microvessel model, Borrelia extravasation across the blood–brain barrier is extremely rare, implying that neuroborreliosis is not caused via direct cytotoxicity.
Linus Wang, Zikai Xia, Anjan Singh, Bhavna Murarka, Nicole Baumgarth, John N. Aucott, Peter C. Searson   +6 more
wiley   +1 more source

Updates on Toll‐Like Receptor 10 Research

European Journal of Immunology, Volume 55, Issue 5, May 2025.
Toll‐like receptor 10 (TLR10 or CD290) shares the same structural organization as the other TLRs but shows a unique expression pattern and distinct functional activities yet to be fully elucidated. This review summarizes key steps and recent updates on TLR10 research including open questions and future perspectives.
Federica Riva, Marta Muzio
wiley   +1 more source

Clinical features, treatment options and outcomes in primary cutaneous B‐cell lymphomas: a real‐world, multicenter, retrospective study

International Journal of Dermatology, Volume 64, Issue 5, Page 882-889, May 2025.
Clinical features, treatment options and outcomes in PCBCL. Abstract Background Primary cutaneous B‐cell lymphomas (PCBCLs) are rare cutaneous neoplasms with limited literature regarding treatment options and associated treatment outcomes. This study aimed to investigate and present real‐world treatment outcomes in patients with PCBCLs.
Vasiliki Nikolaou, Ioannis‐Alexios Koumprentziotis, Evangelia Papadavid, Aikaterini Patsatsi, Stavrianna Diavati, Antonios Tsimpidakis, Sabine Kruger‐Krasagakis, Aikaterini Doxastaki, Leonidas Marinos, Stella Kaliampou, Maria Gerochristou, Marios Koumourtzis, Vasiliki Pappa, Efrosini Kypraiou, Vassilis Kouloulias, Konstantinos Angelopoulos, Alexandros Machairas, Theodoros Vassilakopoulos, Vasiliki Papadopoulou, Athanasios Tsamaldoupis, Elisavet Georgiou, Triantafyllia Koletsa, Alexander Stratigos, Marina Siakantaris, Maria Angelopoulou   +24 more
wiley   +1 more source

The genetic diversity of Borrelia afzelii is not maintained by the diversity of the rodent hosts. [PDF]

, 2018
Small mammals are essential in the enzootic cycle of many tick-borne pathogens (TBP). To understand their contribution to the genetic diversity of Borrelia afzelii, the most prevalent TBP in questing Ixodes ricinus, we compared the genetic variants of B.
Coipan, Claudia E, Hofmeester, Tim R, Sprong, Hein, Takumi, Katsuhisa, van Duijvendijk, Gilian L A   +4 more
core   +1 more source

Prognostic factors and long‐term outcome in dogs diagnosed with primary and secondary immune thrombocytopenia in Ireland

Journal of Small Animal Practice, Volume 66, Issue 5, Page 305-313, May 2025.
Objectives The objectives of this study were to describe the outcome and prognostic factors in dogs diagnosed with primary and secondary immune thrombocytopenia (ITP). Materials and Methods Medical records of dogs diagnosed with primary and secondary ITP in a referral hospital in Ireland were retrospectively evaluated.
E. López‐Bailén, A. Duclos, D. Mullany, K. Le Boedec, B. Cuq   +4 more
wiley   +1 more source

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis [PDF]

, 2015
Objectives: Prompt antibiotic treatment of early stage Lyme borreliosis (LB) prevents progression to severe multisystem disease. There is a clinical need to improve the diagnostic specificity of early stage Lyme assays in the period prior to the mounting
Alessandra Luchini, Benjamin H. Espina, Benjamin Lepene, Christine Mayuga, Donald M. Poretz, Emanuel F. III Petricoin, Gilbert R. Irwin, Ketul Shah, Lance A. Liotta, Mary Frekko Kilavos, Ross Dunlap, Ruben Magni, Sally Rucker, Samuel M. Shor, Temple A. Douglas, Virginia Espina   +15 more
core   +3 more sources

Results of Practical Evaluation of the Optimized Method for Multilocus Sequence Analysis of Pathogenic Borrelia burgdorferi sensu lato Group

Problems of Particularly Dangerous Infections
The aim of the study was to test the possibility of identifying isolates of pathogenic Borrelia burgdorferi sensu lato by the specificity of linked sequences of their recA and ospA gene loci, i.e. using the optimized multilocus sequence analysis (MLSA) method.Materials and methods.
E. S. Krupinskaya, E. I. Korenberg, K. A. Golidonova, N. B. Gorelova, V. A. Matrosova   +4 more
openaire   +2 more sources

Molecular analysis of decorin-binding protein A (DbpA) reveals five major groups among European Borrelia burgdorferi sensu lato strains with impact for the development of serological assays and indicates lateral gene transfer of the dbpA gene

International Journal of Medical Microbiology, 2006
The Borrelia (B.) burgdorferi adhesin DbpA (decorin-binding protein A) is a valuable antigen for serodiagnosis of Lyme borreliosis and a promising candidate for a vaccine. To investigate the heterogeneity of DbpA, we aligned DNA sequences of 83 different dbpA genes (37 from the database, where the majority of sequences belong to B.
Gereon Goettner, Volker Fingerle, Sandra Rogge, Ulrike Schulte-Spechtel, Bettina Wilske   +4 more
openaire   +2 more sources

Lyme Disease and the Workplace [PDF]

, 2019
{Excerpt] Lyme disease, an infection by the bacterium Borrelia burgdorferi, was named after a Connecticut town where a group of arthritis cases in children appeared in the early 1970s.
Brown, Nellie J
core   +1 more source