First insights in the variability of Borrelia recurrentis genomes [PDF]
PLoS Neglected Tropical Diseases, 2017 BackgroundBorrelia recurrentis is the causative agent of louse-borne relapsing fever, endemic to the Horn of Africa. New attention was raised in Europe, with the highest number of cases (n = 45) reported among migrants in 2015 in Germany and sporadically
Gabriele Margos +2 more
exaly +9 more sources
The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii [PDF]
PLoS Genetics, 2008 In an effort to understand how a tick-borne pathogen adapts to the body louse, we sequenced and compared the genomes of the recurrent fever agents Borrelia recurrentis and B. duttonii. The 1,242,163-1,574,910-bp fragmented genomes of B. recurrentis and B.
Guillaume Blanc +2 more
exaly +9 more sources
Borrelia recurrentis in Head Lice, Ethiopia [PDF]
Emerging Infectious Diseases, 2013 Since the 1800s, the only known vector of Borrelia recurrentis has been the body louse. In 2011, we found B. recurrentis DNA in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia.
Amina Boutellis +6 more
doaj +10 more sources
A Novel Animal Model of Borrelia recurrentis Louse-Borne Relapsing Fever Borreliosis Using Immunodeficient Mice [PDF]
PLoS Neglected Tropical Diseases, 2009 Louse-borne relapsing fever (LBRF) borreliosis is caused by Borrelia recurrentis, and it is a deadly although treatable disease that is endemic in the Horn of Africa but has epidemic potential.
Christer Larsson
exaly +12 more sources
Borrelia recurrentis Employs a Novel Multifunctional Surface Protein with Anti-Complement, Anti-Opsonic and Invasive Potential to Escape Innate Immunity [PDF]
PLoS ONE, 2009 Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
Peter F Zipfel +2 more
exaly +11 more sources
Human Complement Regulators C4b-Binding Protein and C1 Esterase Inhibitor Interact with a Novel Outer Surface Protein of Borrelia recurrentis [PDF]
PLoS Neglected Tropical Diseases, 2010 The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B.
Sally J Cutler +2 more
exaly +10 more sources
Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis [PDF]
Nature CommunicationsBorrelia recurrentis, the agent of louse-borne relapsing fever, causes a poverty-associated, infectious disease of high mortality. Here, we identified and characterized five Complement targeting and Host Interacting proteins, ChiA to ChiE displaying ...
Florian Röttgerding +13 more
doaj +5 more sources
The First Immunocompetent Mouse Model of Strictly Human Pathogen, Borrelia recurrentis. [PDF]
Infection and Immunity, 2021 The spirochetal bacterium Borrelia recurrentis causes louse-borne relapsing fever (LBRF). Borrelia recurrentis is unique because, as opposed to other Borrelia spirochetes, this strictly human pathogen is transmitted by lice.
Artem S Rogovskyy +2 more
exaly +5 more sources
Relapsing fever revisited: New insights into neglected borrelial infections. [PDF]
PLoS Neglected Tropical DiseasesWhy revisit our understanding of relapsing fever and their causative spirochaetes? We have seen many existing paradigms of relapsing fever borreliosis challenged over recent years, largely facilitated through technological molecular biological ...
Sally J Cutler
doaj +2 more sources
Head lice as vectors of pathogenic microorganisms [PDF]
Tropical Medicine and Health, 2023 Body lice and head lice are the most common ectoparasites of humans. Head lice (Pediculus humanus capitis) occur worldwide in children and their caretakers, irrespective of their social status.
Hermann Feldmeier
doaj +2 more sources