First insights in the variability of Borrelia recurrentis genomes [PDF]
BackgroundBorrelia recurrentis is the causative agent of louse-borne relapsing fever, endemic to the Horn of Africa. New attention was raised in Europe, with the highest number of cases (n = 45) reported among migrants in 2015 in Germany and sporadically
Gabriele Margos +2 more
exaly +7 more sources
The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii [PDF]
In an effort to understand how a tick-borne pathogen adapts to the body louse, we sequenced and compared the genomes of the recurrent fever agents Borrelia recurrentis and B. duttonii. The 1,242,163-1,574,910-bp fragmented genomes of B. recurrentis and B.
Guillaume Blanc +2 more
exaly +6 more sources
A Novel Animal Model of Borrelia recurrentis Louse-Borne Relapsing Fever Borreliosis Using Immunodeficient Mice [PDF]
Louse-borne relapsing fever (LBRF) borreliosis is caused by Borrelia recurrentis, and it is a deadly although treatable disease that is endemic in the Horn of Africa but has epidemic potential.
Christer Larsson +3 more
exaly +9 more sources
Borrelia recurrentis in Head Lice, Ethiopia [PDF]
Since the 1800s, the only known vector of Borrelia recurrentis has been the body louse. In 2011, we found B. recurrentis DNA in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia.
Amina Boutellis +6 more
doaj +8 more sources
Human Complement Regulators C4b-Binding Protein and C1 Esterase Inhibitor Interact with a Novel Outer Surface Protein of Borrelia recurrentis [PDF]
The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B.
Sally Cutler +2 more
exaly +3 more sources
Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis [PDF]
Borrelia recurrentis, the agent of louse-borne relapsing fever, causes a poverty-associated, infectious disease of high mortality. Here, we identified and characterized five Complement targeting and Host Interacting proteins, ChiA to ChiE displaying ...
Florian Röttgerding +13 more
doaj +4 more sources
Borrelia recurrentis Employs a Novel Multifunctional Surface Protein with Anti-Complement, Anti-Opsonic and Invasive Potential to Escape Innate Immunity [PDF]
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
Peter Zipfel +2 more
exaly +3 more sources
Commentary on Seersholm Et al.: Yersinia pestis Infection Is Not Synonymous With Deadly Plague in Neolithic Scandinavia. [PDF]
ABSTRACT Objectives Emerging genomic evidence has identified ancestral strains of Yersinia pestis in ancient human populations, which has sparked debates about its pathogenic role in later Neolithic societies. Here, we review published evidence linking anthropological and biological data reflecting the past natural history of Y.
Oumarou Hama H +3 more
europepmc +2 more sources
Ancient dental pulp: Masterpiece tissue for paleomicrobiology
Introduction Dental pulp with special structure has become a good reference sample in paleomicrobiology‐related blood‐borne diseases, many pathogens were detected by different methods based on the diagnosis of nucleic acids and proteins.
Ba Hoang Anh Mai +2 more
doaj +2 more sources
Head lice as vectors of pathogenic microorganisms [PDF]
Body lice and head lice are the most common ectoparasites of humans. Head lice (Pediculus humanus capitis) occur worldwide in children and their caretakers, irrespective of their social status.
Hermann Feldmeier
doaj +2 more sources

