First insights in the variability of Borrelia recurrentis genomes [PDF]
PLoS Neglected Tropical Diseases, 2017 BackgroundBorrelia recurrentis is the causative agent of louse-borne relapsing fever, endemic to the Horn of Africa. New attention was raised in Europe, with the highest number of cases (n = 45) reported among migrants in 2015 in Germany and sporadically
Durdica Marosevic +2 more
exaly +9 more sources
The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii [PDF]
PLoS Genetics, 2008 In an effort to understand how a tick-borne pathogen adapts to the body louse, we sequenced and compared the genomes of the recurrent fever agents Borrelia recurrentis and B. duttonii. The 1,242,163-1,574,910-bp fragmented genomes of B. recurrentis and B.
Stéphane Audic +2 more
exaly +9 more sources
A Novel Animal Model of Borrelia recurrentis Louse-Borne Relapsing Fever Borreliosis Using Immunodeficient Mice [PDF]
PLoS Neglected Tropical Diseases, 2009 Louse-borne relapsing fever (LBRF) borreliosis is caused by Borrelia recurrentis, and it is a deadly although treatable disease that is endemic in the Horn of Africa but has epidemic potential.
Sven Bergstrom
exaly +11 more sources
Borrelia recurrentis in Head Lice, Ethiopia [PDF]
Emerging Infectious Diseases, 2013 Since the 1800s, the only known vector of Borrelia recurrentis has been the body louse. In 2011, we found B. recurrentis DNA in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia.
Amina Boutellis +6 more
doaj +10 more sources
Borrelia recurrentis Employs a Novel Multifunctional Surface Protein with Anti-Complement, Anti-Opsonic and Invasive Potential to Escape Innate Immunity [PDF]
PLoS ONE, 2009 Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
Sally J Cutler +2 more
exaly +6 more sources
Human Complement Regulators C4b-Binding Protein and C1 Esterase Inhibitor Interact with a Novel Outer Surface Protein of Borrelia recurrentis [PDF]
PLoS Neglected Tropical Diseases, 2010 The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B.
Sally J Cutler +2 more
exaly +6 more sources
Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis [PDF]
Nature CommunicationsBorrelia recurrentis, the agent of louse-borne relapsing fever, causes a poverty-associated, infectious disease of high mortality. Here, we identified and characterized five Complement targeting and Host Interacting proteins, ChiA to ChiE displaying ...
Florian Röttgerding +13 more
doaj +3 more sources
The First Immunocompetent Mouse Model of Strictly Human Pathogen, Borrelia recurrentis [PDF]
Infection and Immunity, 2021 The spirochetal bacterium Borrelia recurrentis causes louse-borne relapsing fever (LBRF). Borrelia recurrentis is unique because, as opposed to other Borrelia spirochetes, this strictly human pathogen is transmitted by lice.
Artem S Rogovskyy +2 more
exaly +5 more sources
Hemorrhagic Diathesis in Borrelia recurrentis Infection Imported to Germany [PDF]
Emerging Infectious Diseases, 2016 To the Editor: Relapsing fevers are paroxysmal bloodstream infections caused by spirochetes of the genus Borrelia. Louseborne relapsing fever (LBRF; i.e., epidemic relapsing fever) is caused by B. recurrentis and transmitted by the human body louse (Pediculus humanus).
Christian Keller +7 more
doaj +4 more sources
Louse-borne relapsing fever (Borrelia recurrentis infection). [PDF]
Epidemiol Infect, 2019 Louse-borne relapsing fever (LBRF) is an epidemic disease with a fascinating history from Hippocrates' times, through the 6th century 'Yellow Plague', to epidemics in Ireland, Scotland and England in the 19th century and two large Afro-Middle Eastern ...
Warrell DA.
europepmc +6 more sources