Results 91 to 100 of about 15,937 (243)

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, Volume 12, Issue 42, November 13, 2025.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source

Foreword: Seminars in Research 2014 Joint Experiences in Rheumatology and Dermatology [PDF]

, 2016
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Costanzo, Antonio, Spinelli, FRANCESCA ROMANA   +1 more
core   +1 more source

Vasoactive neuropeptide dysregulation: A novel mechanism of microvascular dysfunction in vascular cognitive impairment

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Neuropeptide dysregulation and microvascular injury are involved in pathogenesis of vascular cognitive impairment (VCI); however, the underlying etiology of this pathological axis remains unclear. METHODS We investigated pathological mediators across varying severities of VCI in a rat model of chronic cerebral hypoperfusion (CCH).
Willians Tambo, Keren Powell, Steven Wadolowski, Prashin Unadkat, Eric H. Chang, Christopher LeDoux, Daniel Sciubba, Ping Wang, Patricio Huerta, Chunyan Li   +9 more
wiley   +1 more source

Two-years therapy with bosentan of pulmonary arterial hypertension related to connective tissue diseases

Reumatismo, 2011
Objective: Pulmonary arterial hypertension (PAH) is a rare but severe complication of connective tissue diseases (CTD), with a negative impact on patients survival.
M. Rizzo, S. Pontarollo, F. Tiso, R. Montisci, H. Marotta, F. Tona, S. Iliceto, F. Cozzi   +7 more
doaj   +1 more source

Echocardiographic Changes and Long-Term Clinical Outcomes in Pediatric Patients With Pulmonary Arterial Hypertension Treated With Bosentan for 72 Weeks: A Post-hoc Analysis From the FUTURE 3 Study [PDF]

, 2021
Maurice Beghetti, Rolf M.F. Berger, Damien Bonnet, Simon Grill, Catherine Lesage, Jean‐Christophe Lemarié, D. Dunbar Ivy   +6 more
openalex   +1 more source

Effect of Bosentan on Exercise Capacity and Clinical Worsening in Patients with Dual down and Eisenmenger Syndrome

Clinical Medicine Insights: Cardiology, 2013
This single-center, retrospective analysis evaluated long-term bosentan treatment in adult patients (n = 7) with both Down and Eisenmenger syndromes (DS-ES).
Giorgio Serino, Marco Guazzi, Angelo Micheletti, Carlo Lombardi, Rossella Danesi, Diana Negura, Mario Carminati, Massimo Chessa   +7 more
doaj   +1 more source

Capillaroscopy in 2016 : new perspectives in systemic sclerosis [PDF]

, 2016
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by early impairment of the microvascular system. Nailfold microangiopathy and decreased peripheral blood perfusion are typical clinical aspects of SSc.
Cutolo, M, Llado, A, Paolino, S, Pizzorni, C, Ruaro, B, Smith, Vanessa, Sulli, A   +6 more
core   +1 more source

Combined aerobic and resistance exercise training decreases peripheral but not central artery wall thickness in subjects with type 2 diabetes [PDF]

, 2015
Objective Little is known about the impact of exercise training on conduit artery wall thickness in type 2 diabetes. We examined the local and systemic impact of exercise training on superficial femoral (SFA), brachial (BA), and carotid artery (CA) wall
A Maiorana, A Maiorana, A Suessenbacher, AJ Maiorana, BL Langille, BL Langille, DH O’Leary, DH Thijssen, DH Thijssen, DH Thijssen, DH Thijssen, DH Thijssen, DH Thijssen, Dick H. J. Thijssen, DJ Green, DJ Green, DJ Green, DR Matthews, E Groot de, Fleur Poelkens, GD Xiang, GJ Balady, GK Birk, Inge Van Den Munckhof, J Quilley, K Potter, K Potter, K Watts, KE Sorensen, KJ Rothman, KL Moreau, LE Wagenknecht, LE Wagenknecht, LH Naylor, M Wei, MA Awolesi, Maria T. E. Hopman, MJ Joyner, MW Lorenz, NJ Rowley, NJ Rowley, NP Kadoglou, O Monfredi, PA Metcalf, SC Newcomer, SH Kim, SY Jae, T Watarai, TH Marwick, Tim H. A. Schreuder, TK Paul, TM Tinken, TS Church, TV Perneger   +53 more
core   +1 more source

Review of bosentan in the management of pulmonary arterial hypertension

Vascular Health and Risk Management, 2008
Eli Gabbay1, John Fraser2, Keith McNeil31Western Australian Lung Transplant Unit and Pulmonary Hypertension Service, Royal Perth Hospital, Western Australia, Australia; 2Critical Care Research Group, The Prince Charles Hospital, Rode Road, Chermside ...
Eli Gabbay, John Fraser, Keith McNeil
doaj  

Effect of bosentan on intimal hyperplasia of carotid artery anastomoses in rabbits

Türk Kardiyoloji Derneği Arşivi, 2014
Objectives: We investigated the effect of bosentan on intimal hyperplasia of carotid artery anastomoses in rabbits. Study design: Eighteen New Zealand male rabbits were randomized into two groups, as drug (Group B) and non-drug (Group A).
Artan Jahollari, Anar Emrahov, Murat Tavlaşoğlu, Mustafa Kürklüoğlu, Mehmet Ali Şahin, Adem Güler, Ertuğrul Özal, Mehmet Arslan   +7 more
doaj   +1 more source