Results 111 to 120 of about 8,768 (188)

Absorption, excretion, and metabolism of the endothelin receptor antagonist bosentan in healthy male subjects

, 1999
The absorption, excretion, and metabolism of the endothelin receptor antagonist bosentan was investigated in healthy male subjects by administration of 14C-labeled compound.
Weber, Cornelia, Hopfgartner, Gerard, Gasser, R.   +2 more
core  

Activin A-Endothelin-1 Axis Governs Pulmonary Vascular Remodeling: Mechanistic Basis for Emerging Therapies in PAH. [PDF]

Arterioscler Thromb Vasc Biol
Faizah NN, Ryanto GRT, Kencana SMS, Suzuki Y, Hara T, Otake H, Emoto N.   +6 more
europepmc   +1 more source

Heterogeneity in the efficacy of bosentan for hypertensive nephropathy: a study on individualized benefit prediction models based on pathological subtyping and dynamic trajectories. [PDF]

Ann Med
Yu X, Gong X, Wang B, Ji Y, Wu R, Wang W, Huang M, Nie S, Cai G, Chen X, Feng Z.   +10 more
europepmc   +1 more source

Disproportionality analysis of adverse events associated with endothelin receptor antagonists based on the FDA adverse event reporting system (FAERS). [PDF]

Front Cardiovasc Med
Han L, Li S, Liao J, Yin Q, He C, Wang Y, Li G, Bian Y.   +7 more
europepmc   +1 more source

Selection of Endothelin Receptor Antagonists in the Treatment of Pulmonary Arterial Hypertension: A Comprehensive Narrative Review. [PDF]

Adv Ther
Habib NG, Adhia A, Lopez D, Sandros M, Guichard P.   +4 more
europepmc   +1 more source

Successful treatment of refractory chilblain lupus erythematosus with bosentan. [PDF]

Rheumatology (Oxford)
Gunawardana S, Clarke AJ, Lloyd-Lavery A, Dubey S.   +3 more
europepmc   +1 more source

A K_Ca 2.2/2.3 Opener Reverses ET-1-Induced NLRP3 Activation in Hypertensive Mice Corpora Cavernosa. [PDF]

Biomolecules
Sobrano Fais R, Comerma-Steffensen SG, Pinilla E, Matchkov VV, Tostes R, Silva Carneiro F, Simonsen U.   +6 more
europepmc   +1 more source

Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes

Experimental evidence suggests that endothelin 1 (ET-1) is involved in the development of retinal microvascular abnormalities induced by diabetes. The effects of ET-1 are mediated by endothelin A- and B-receptors (ETA and ETB).
Hernández Pascual, Cristina, Arias, Luis, Sampedro, Joel, Ticó, Josep Ramon, Solà-Adell, Cristina, Guerrero, Marta, Ramos, Hugo, Durán, Vicente, Simó, Rafael, Bogdanov, Patricia, Simó-Servat, Olga, Garcia-Ramírez, Marta, Montoro, Bruno, Suñé-Negre, Josep Maria   +13 more
core  

Systematic Review of the Application of Pulmonary Hypertension Treatments in Ventricular Septal Defect, Pulmonary Atresia, and Major Aortopulmonary Collateral Arteries. [PDF]

J Clin Med
Hirono K, Uchida K, Ishii T, Ishida H, Takatsuki S, Fukushima H, Inai K, Hosokawa S, Ishizaki R, Sawada H, Sumitomo NF, Chida-Nagai A, Ishikawa Y, Motoki H, Yao A, Kogaki S, Yamagishi H, Doi S.   +17 more
europepmc   +1 more source

Silver nanoparticles-based green fluorescent probe for determination of Bosentan in pharmaceutical formulation and spiked plasma samples. [PDF]

BMC Chem
Trabik YA, Ismail RA, Ayad MF, Hussein LA.   +3 more
europepmc   +1 more source