Results 121 to 130 of about 1,434 (169)
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Boswellic acids and protease activities
Phytomedicine, 1996The involvement of human leukocyte elastase (HLE) in several inflammatory processes and the reported inhibitory effect of ursolic acid on HLE has prompted the authors to start investigation on the effects of acetyl-11-keto-β-boswellic acid (AKBA) on serine proteinases including HLE.
B, Rall, H P, Ammon, H, Safayhi
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Metabolism of Boswellic Acids in Vitro and in Vivo
Drug Metabolism and Disposition, 2008Boswellia serrata resin dry extract is among the few herbal remedies designated with an orphan drug status for the treatment of peritumoral brain edema. In addition, boswellic acids (BAs), the main active ingredients of B. serrata extracts, have potent anti-inflammatory properties, and may represent promising agents for the treatment of inflammatory ...
Phillip, Krüger +9 more
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Mechanism of antiinflammatory actions of curcumine and boswellic acids
Journal of Ethnopharmacology, 1993Curcumine from Curcuma longa and the gum resin of Boswellia serrata, which were demonstrated to act as anti-inflammatories in in vivo animal models, were studied in a set of in vitro experiments in order to elucidate the mechanism of their beneficial effects.
Hermann P T Ammon +2 more
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Anti-inflammatory actions of boswellic acids
Phytomedicine, 1996Boswellic acids (BA) demonstrated dose-related anti-inflammatory activity (AIA) in acute tests of carrageenan-, histamine- and dextran-induced edema in rats and mice. It elicited inhibitory action on vascular permeability in mice induced by acetic acid.
G B, Singh, S, Singh, S, Bani
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The potential role of boswellic acids in cancer prevention and treatment
Cancer Letters, 2016Despite the extensive research carried out in the field of cancer therapeutics, cancer is one of the most dreadful diseases in the world with no definitive treatment to date. The key attributes responsible for this are the various limiting factors associated with conventional chemotherapeutics that primarily include adverse side-effects and development
Nand Roy +2 more
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Toxicity and safety evaluation of boswellic acids
Phytomedicine, 1996The acute, sub-acute and chronic toxicity studies on boswellic acids (BAs) were carried out on mice, rats and monkeys. BAs did not cause any mortality in rats and mice when administered orally and intraperitoneally in doses up to 2 g/kg. Daily oral administration of BAs in three doses (low and very high) to rats and monkeys revealed no significant ...
G B, Singh, S, Bani, S, Singh
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Inhibition by Boswellic Acids of Human Leukocyte Elastase
Journal of Pharmacology and Experimental Therapeutics, 1997Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene biosynthesis and exert potent anti-inflammatory effects. Screening for additional effects of boswellic acids on further proinflammatory pathways, we observed that acetyl-11-keto-beta-boswellic acid, an established direct, nonredox ...
Hermann P T Ammon +2 more
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Modulation of Pgp Function by Boswellic Acids
Planta Medica, 2006Boswellic acids, the main active ingredients of Boswellia serrata, are gaining more and more importance in the treatment of peritumoural oedema and chronic inflammatory diseases. They may be even considered as alternative drugs to corticosteroids in reducing cerebral peritumoural oedema. An important focus for drugs acting in the central nervous system
Claudia-Carolin, Weber +4 more
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Boswellic Acids: Biological Actions and Molecular Targets
Current Medicinal Chemistry, 2006Gum resin extracts of Boswellia species have been traditionally applied in folk medicine for centuries to treat various chronic inflammatory diseases, and experimental data from animal models and studies with human subjects confirmed the potential of B. spec extracts for the treatment of not only inflammation but also of cancer.
Daniel, Poeckel, Oliver, Werz
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Boswellic acids as promising agents for the management of brain diseases
Life Sciences, 2023Boswellic acid (BA)s are pentacyclic triterpenic acids present in gum resin of Boswellia species (such as B. serrata and B. carterii). They possess a variety of pharmacological effects such as anti-inflammatory, anti-oxidant, and anti-excitotoxic effects. These properties may have potential therapeutic implication in neurological disorders.
Arezoo Rajabian +4 more
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