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Pharmacokinetic study of 11-Keto β-Boswellic Acid
Phytomedicine, 2004Boswellia serrata has been used in traditional medicine for treatment of inflammatory diseases since antiquity. However human kinetic studies are lacking for this. Hence to better elucidate its effects in humans and determine its optimal dosing, this study was planned.Twelve healthy adult men volunteers were given capsule Wok Vel containing 333 mg of ...
S, Sharma +5 more
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Synthesis and cytotoxic activity of boswellic acid analogues
Phytochemistry Letters, 2016Abstract Fifteen stereoisomers of boswellic acid analogues bearing 2-OH, 24-OH, 3-keto or 2-OH, 3-OH, 24-OH groups were synthesised and their structures were confirmed using 1 H NMR, 13 C NMR, 2D NMR and HRMS. The cytotoxic activities of these compounds toward three human tumor cell lines, K562, PC3 and A549, were evaluated.
Peihong Fan +5 more
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Crystallographic Analysis of Acetyl β -boswellic acid
Crystal Research and Technology, 2001The crystal structure of the title compound (3α-acetoxy-urs-12-en-24-oic acid, C 32 H 50 O 4 ) has been determined by X-ray crystallographic techniques. The compound crystallizes into orthorhombic space group P2 1 2 1 2 with unit cell parameters: a = 12.773(2), b=16.381(4), c=27.929(7)A. The structure has been solved by direct methods and refined to R =
V. Rajnikant +5 more
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Bioavailability of boswellic acids: in vitro/in vivo correlation
Pharmaceutical Chemistry Journal, 2007Extract of Boswellia sacra (incense tree), the main active components of which are boswellic acids, is used for the treatment of rheumatoid arthritis and gout. Boswellic acids suppress leukotriene biosynthesis in neutrophilic granulocytes by non-redox, noncompetitive inhibition of 5-lipoxygenase.
M. V. Karlina +3 more
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Determination of five boswellic acids in Boswellia serrata
China Journal of Chinese Materia Medica, 2011Objective To develop an HPLC method for determinating the contents of five boswellic acids in Boswellia serrata. Method Analysis was performed on a zorbax SB C18 column eluted with acetonitrile-0.1% phosphoric acid in water as mobile phases in gradient elution and the detection wavelengths were 210 nm and 250 nm.
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Modulation of the immune system by extracts and boswellic acids
Phytomedicine, 2010Hermann P T Ammon
exaly