Results 171 to 180 of about 2,756 (213)
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Anti-inflammatory actions of boswellic acids
Phytomedicine, 1996Boswellic acids (BA) demonstrated dose-related anti-inflammatory activity (AIA) in acute tests of carrageenan-, histamine- and dextran-induced edema in rats and mice. It elicited inhibitory action on vascular permeability in mice induced by acetic acid.
G B, Singh, S, Singh, S, Bani
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Toxicity and safety evaluation of boswellic acids
Phytomedicine, 1996The acute, sub-acute and chronic toxicity studies on boswellic acids (BAs) were carried out on mice, rats and monkeys. BAs did not cause any mortality in rats and mice when administered orally and intraperitoneally in doses up to 2 g/kg. Daily oral administration of BAs in three doses (low and very high) to rats and monkeys revealed no significant ...
G B, Singh, S, Bani, S, Singh
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Boswellic Acids: Biological Actions and Molecular Targets
Current Medicinal Chemistry, 2006Gum resin extracts of Boswellia species have been traditionally applied in folk medicine for centuries to treat various chronic inflammatory diseases, and experimental data from animal models and studies with human subjects confirmed the potential of B. spec extracts for the treatment of not only inflammation but also of cancer.
Daniel, Poeckel, Oliver, Werz
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Acta Physiologiae Plantarum, 2012
Boswellia serrata Roxb. is a source of several bioactive triterpenoids. Boswellic acid, obtained from oleo-gum resin of the tree, is a major potentially bioactive and medicinal compound. Unrestricted exploitation of its natural resource has led to its listing among the threatened and endangered species.
Ravi Ghorpade +2 more
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Boswellia serrata Roxb. is a source of several bioactive triterpenoids. Boswellic acid, obtained from oleo-gum resin of the tree, is a major potentially bioactive and medicinal compound. Unrestricted exploitation of its natural resource has led to its listing among the threatened and endangered species.
Ravi Ghorpade +2 more
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European Journal of Medicinal Chemistry, 2011
Semi-synthetic analogues of β-boswellic acid (BA) and 11-keto-β-boswellic acid (KBA) were comparatively evaluated for in vitro cytotoxicity against human myeloid leukaemia (HL-60) and human cervical carcinoma (HeLa) cells. 2-Cyano analogues of both the triterpenes were observed to have significant cytotoxicity against both the cells, displaying ...
Rajbir, Kaur +7 more
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Semi-synthetic analogues of β-boswellic acid (BA) and 11-keto-β-boswellic acid (KBA) were comparatively evaluated for in vitro cytotoxicity against human myeloid leukaemia (HL-60) and human cervical carcinoma (HeLa) cells. 2-Cyano analogues of both the triterpenes were observed to have significant cytotoxicity against both the cells, displaying ...
Rajbir, Kaur +7 more
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Modulation of Pgp Function by Boswellic Acids
Planta Medica, 2006Boswellic acids, the main active ingredients of Boswellia serrata, are gaining more and more importance in the treatment of peritumoural oedema and chronic inflammatory diseases. They may be even considered as alternative drugs to corticosteroids in reducing cerebral peritumoural oedema. An important focus for drugs acting in the central nervous system
Claudia-Carolin, Weber +4 more
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Inhibition by Boswellic Acids of Human Leukocyte Elastase
The Journal of Pharmacology and Experimental Therapeutics, 1997Frankincense extracts and boswellic acids, biologically active pentacyclic triterpenes of frankincense, block leukotriene biosynthesis and exert potent anti-inflammatory effects. Screening for additional effects of boswellic acids on further proinflammatory pathways, we observed that acetyl-11-keto-beta-boswellic acid, an established direct, nonredox ...
H, Safayhi +3 more
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Boswellic acids: a group of medicinally important compounds
Nat. Prod. Rep., 2009This review, containing over 276 references, covers the progress made in the chemistry and bioactivity of this important group of triterpenoids. Though initially known for their anti-inflammatory and anti-arthritic activities through a unique 5-LO inhibition mechanism, boswellic acids have recently attained significance due to their anti-cancer ...
Bhahwal Ali, Shah +2 more
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Topical Boswellic acids for treatment of photoaged skin
Dermatologic Therapy, 2010Boswellic acids (BAs) are pentacyclic triterpenes extracted from the gum resins of the tropical tree Boswellia serrata. They are orally administered in traditional Indian medicine for the treatment of several inflammatory disease and cancer because of their anti-inflammatory and immunomodulatory activities as well as stimulatory effects on fibroblasts.
CALZAVARA PINTON, Piergiacomo +4 more
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Pharmacokinetic study of 11-Keto β-Boswellic Acid
Phytomedicine, 2004Boswellia serrata has been used in traditional medicine for treatment of inflammatory diseases since antiquity. However human kinetic studies are lacking for this. Hence to better elucidate its effects in humans and determine its optimal dosing, this study was planned.Twelve healthy adult men volunteers were given capsule Wok Vel containing 333 mg of ...
S, Sharma +5 more
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