Bothrops venom variation drives niche-specific pharmacology through Ca2+ signalling and membrane damage [PDF]
Snake venom activity exhibits evolutionary patterns within genera and varies according to ecological niche. By examining venoms from species inhabiting distinct environments, niche-specific functional differences can be uncovered. Bothrops, a diverse and
Lachlan A. Bourke +10 more
doaj +2 more sources
Comparative Hemostatic Effects of Bothrops spp. and Daboia russelii Venoms [PDF]
Venoms from Bothrops species and Daboia russelii are among the leading causes of venom-induced coagulopathy and snakebite-related deaths. In this study, we comparatively evaluated the biochemical composition and hemostatic effects of venoms from seven ...
Geovanna M. Malchias-Pires +8 more
doaj +2 more sources
Brazilian Bothrops and Crotalus Snake Venoms as a Source of Antiprotozoal Agents: Unlocking Toxins for Therapeutic Development [PDF]
Leishmaniasis and Chagas disease are neglected tropical diseases that continue to pose significant public health challenges, highlighting the need for new therapeutic strategies.
Tulio Custódio Reis +8 more
doaj +2 more sources
Snakebites by Bothrops taeniatus: characteristics of snakebites involving a rare venomous snake in Brazil [PDF]
Snakebites from the genus Bothrops account for up to 90% of venomous snakebites in Brazil. Among these species, Bothrops taeniatus is considered rare in Brazil, with only one reported case in the literature.
Paula Cristina Yukari Suzaki Fujii +5 more
doaj +2 more sources
Bothrops snakebites usually present systemic bleeding, and the clinical–epidemiological and laboratorial factors associated with the development of this manifestation are not well established.
Jacqueline Sachett +2 more
exaly +3 more sources
Rapid, label-free surface plasmon resonance discrimination between Bothrops and Crotalus venoms using clinical antivenom as the capture reagent. [PDF]
Snake envenoming is recognized as a global health problem, affecting thousands of people every year. One of the main challenges in addressing this issue is the correct identification and treatment of these envenomations, particularly in locations where ...
Ely S F Borges +5 more
doaj +2 more sources
Antimicrobial peptidomes of Bothrops atrox and Bothrops jararacussu snake venoms [PDF]
The worrisome emergence of pathogens resistant to conventional drugs has stimulated the search for new classes of antimicrobial and antiparasitic agents from natural sources. Antimicrobial peptides (AMPs), acting through mechanisms that do not rely on the interaction with a specific receptor, provide new possibilities for the development of drugs ...
Cleópatra Alves da Silva Caldeira +10 more
openaire +4 more sources
Bothrops spp. envenomation and its relationship with ischemic stroke has complex pathogenesis. Local effects such as edema, pain, redness, necrosis, and systemic manifestations like coagulation disorders, thrombosis, renal failure, and hemorrhage have ...
Viviana Alexandra Martínez-Villota +2 more
doaj +1 more source
Lesión renal aguda secundaria a mordedura de serpiente del género bothrops: a propósito de un caso
Introducción: el accidente ofídico es una intoxicación ocasionada por la inoculación de venenoa través de la mordedura de una serpiente, la cual genera alteraciones locales y sistémicas.
Emilio Abuabara-Franco +7 more
doaj +1 more source
Introducción. El ofidismo en Colombia es un problema de salud pública, lo cual se hace evidente al examinar los datos epidemiológicos a nivel latinoamericano, pues el país ocupa el tercer lugar en número de accidentes ofídicos después de Brasil y México.
María José Sevilla-Sánchez +2 more
doaj +1 more source

