Results 71 to 80 of about 12,086 (209)

Engineering Antivenom: Research Progress and Future Directions in Snakebite Envenoming Therapy

Annals of the New York Academy of Sciences, Volume 1562, Issue 1, August 2026.
Snakebite envenoming therapy is evolving from plasma‐derived antivenoms toward rationally engineered therapeutics. Advances in toxicovenomics, structural biology, antibody engineering, computational protein design, recombinant expression, small‐molecule inhibitors, and diagnostics are enabling toxin‐centric development of safer, more effective, and ...
Andreas H. Laustsen
wiley   +1 more source

Caracterización de la enzima similar a trombina del veneno de Bothrops pictus "jergón de costa

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Realizar una caracterización bioquímica y molecular del principio coagulante del veneno de Bothrops pictus. Materiales y métodos. Se realizó la amplificación del gen a partir de cDNA, se analizó la homología de la secuencia nucleotídica y de ...
Dan Vivas-Ruiz, Gustavo A. Sandoval, Fanny Lazo, Edith Rodríguez, Armando Yarlequé, Eladio Flores-Sánchez   +5 more
doaj   +2 more sources

Thrombotic microangiopathy due to Bothrops erythromelas: a case report in Northeast Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2020
Bothrops erythromelas are serpents that belong to the Viperidae family, which are the main species responsible for human snakebites in Ceara State, Northeast Brazil.
Sandra Mara Brasileiro Mota, Polianna Lemos Moura Moreira Albuquerque, Geraldo Bezerra da Silva Júnior, Elizabeth De Francesco Daher   +3 more
doaj   +1 more source

Exploring the Role of Prey Availability as a Driver of Seasonal Shifts in Local Distribution of Vipers (Trimeresurus spp)

Ecology and Evolution, Volume 16, Issue 7, July 2026.
We investigated how seasonal shifts in precipitation and prey availability affect the distribution of arboreal pit vipers (Trimeresurus spp.) in northern Thailand. Trimeresurus were confined to streamside habitats during the dry season but expanded into hillsides during the wet season, mirroring amphibian movements.
Alexander H. Murray, Gregory G. Pandelis, Morgan A. Page, Tanagrit Sumpanpa, Panupong Thammachoti Charunrochana, Jesse M. Meik   +5 more
wiley   +1 more source

Bothrops jararaca

Bothrops jararaca (Wied, 1824)Type locality. Lagoa d’Arara, Mucuri, state of Bahia, Brazil.Distribution. Endemic to Brazil (Plt. 63A). Widespread in Atlantic Forest and Araucaria Forest (Plt. 63A) from low to high elevations (Plt. 63B). Previous maps and taxonomy in Campbell and Lamar (2004). Observed in the field in primary and disturbed forest (
Nogueira, Cristiano C., Argôlo, Antonio J. S., Arzamendia, Vanesa, Azevedo, Josué A., Barbo, Fausto E., Bérnils, Renato S., Bolochio, Bruna E., Borges-Martins, Marcio, Brasil-Godinho, Marcela, Braz, Henrique, Buononato, Marcus A., Cisneros-Heredia, Diego F., Colli, Guarino R., Costa, Henrique C., Franco, Francisco L., Giraudo, Alejandro, Gonzalez, Rodrigo C., Guedes, Thaís, Hoogmoed, Marinus S., Marques, Otavio A. V., Montingelli, Giovanna G., Passos, Paulo, Prudente, Ana L. C., Rivas, Gilson A., Sanchez, Paola M., Serrano, Filipe C., Silva Jr., Nelson J., Strüssmann, Christine, Vieira-Alencar, João Paulo S., Zaher, Hussam, Sawaya, Ricardo J., Martins, Marcio   +31 more
openaire   +4 more sources

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 7, Page 1403-1426, July 2026.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Development of a sensitive enzyme immunoassay (ELISA) for specific identification of Lachesis acrochorda venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
The snake genus Lachesis provokes 2 to 3% of snakebites in Colombia every year. Two Lachesis species, L. acrochorda and L. muta, share habitats with snakes from another genus, namely Bothrops asper and B. atrox.
V Núñez Rangel, M Fernández Culma, P Rey-Suárez, JA Pereañez   +3 more
doaj   +1 more source

A sensory ecology approach to understanding snakebites: Influence of sensory cues on the strike of the lancehead pitviper

Journal of Zoology, Volume 329, Issue 3, Page 237-246, July 2026.
Snakes are notable for having a broad range of predators and one of the most diverse repertoires of defensive behaviors. During heightened responses to aversive stimuli, one of the behaviors displayed is the venomous bite, particularly relevant because it triggers snakebite incidents in humans.
J. M. Alves‐Nunes, A. Fellone, R. H. Willemart, O. A. V. Marques   +3 more
wiley   +1 more source

Complete Mitochondrial Genome of Ovophis makazayazaya (Viperidae, Crotalinae) and Phylogenetic Analysis

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study sequenced and annotated the complete 17,230 bp mitochondrial genome of Ovophis makazayazaya, which contains 13 protein‐coding genes (PCGs), 2 rRNAs, 22 tRNAs, and a D‐loop region, with a significant AT bias (57.2%). Phylogenetic analyses confirmed its placement within Crotalinae, and all PCGs showed evidence of purifying selection (Ka/Ks < 1)
Yuheng Jiang, Yuhao Nie, Zhiqiang Ge
wiley   +1 more source