Results 61 to 70 of about 11,918 (210)
Engineering Antivenom: Research Progress and Future Directions in Snakebite Envenoming Therapy
Snakebite envenoming therapy is evolving from plasma‐derived antivenoms toward rationally engineered therapeutics. Advances in toxicovenomics, structural biology, antibody engineering, computational protein design, recombinant expression, small‐molecule inhibitors, and diagnostics are enabling toxin‐centric development of safer, more effective, and ...
Andreas H. Laustsen
wiley +1 more source
Modelagem de nicho ecológico de bothrops atrox e bothrops marajoensis
The evolution of climatic niches happens more slowly than speciation processes, meaning that closely related species may end up sharing the same ecological parameters.
Costa, Laisla Cagliari
core
We investigated how seasonal shifts in precipitation and prey availability affect the distribution of arboreal pit vipers (Trimeresurus spp.) in northern Thailand. Trimeresurus were confined to streamside habitats during the dry season but expanded into hillsides during the wet season, mirroring amphibian movements.
Alexander H. Murray +5 more
wiley +1 more source
variant data for Bothrops moojeni, including variant and invariant sites; filtered for coverage >=10x and quality >=20 and phased using read-backed ...
Singhal, Sonal +7 more
core +1 more source
Allopurinol attenuates acute kidney injury following Bothrops jararaca envenomation. [PDF]
Snakebites have been recognized as a neglected public health problem in several tropical and subtropical countries. Bothrops snakebites frequently complicate with acute kidney injury (AKI) with relevant morbidity and mortality.
Pedro Henrique França Gois +9 more
doaj +1 more source
Ontogenetic variability of Bothrops atrox and Bothrops asper snake venoms from Colombia
The lancehead snakes Bothrops asper and Bothrops atrox inflict 70-90% of the 3000 bites reported every year in Colombia. In this work, the venoms of B. atrox from Meta (Villavicencio, 33 specimens) and B. asper from Antioquia (San Carlos, 45 specimens), all of them born in captivity, were obtained at different ages (0-6 months; 1, 2 and 3-years old ...
Saldarriaga Córdoba, Mónica María +5 more
openaire +4 more sources
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Introduction: Renal complications following snakebites remain poorly understood due to insufficient evidence. Observational studies have limitations in determining precise frequency.
Castaño Hernández, Ingrid Tatiana +3 more
doaj +1 more source
Este trabalho tem como objetivo relatar um caso de acidente vascular cerebral hemorrágico, associado à acidente ofídico por serpente do gênero bothrops e hipertensão arterial sistêmica grave.
Amanda Silva Machado +3 more
doaj +1 more source

