Results 61 to 70 of about 11,751 (190)

The many dimeric faces of Lys49 PLA2‐like proteins: Conformational plasticity and membrane binding drive functional dimer states

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Lys49 secreted phospholipase A2‐like proteins (sPLA2s) are major myotoxins in viperid snake venoms, causing rapid muscle damage in envenomation. Beyond their clinical relevance, these small non‐catalytic proteins provide a model to study how quaternary structure and conformational dynamics enable catalysis‐independent membrane disruption ...
Diane C. A. Lima   +4 more
wiley   +1 more source

Abstracts

open access: yes, 2021
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue S2, October 2021.
wiley   +1 more source

PRELIMINARY PHYTOCHEMISTRY ASSESSMENT OF Heliconia rostrata AND THE POTENTIAL INHIBITORY ACTIVITY OF SOME EFFECTS OF THE Bothrops asper (mapanà X) VENOM

open access: yes, 2019
Algunas especies de la familia Heliconaceae han demostrado capacidad neutralizante parcial/total de las actividades letal, hemolítica indirecta, hemorrágica, proteolítica, coagulante, mionecrosante y edematizante del veneno de Bothrops asperjuan ...
Vargas, Leidy J   +5 more
core   +2 more sources

Reporte de Melanomys caliginosus (RODENTIA: CRICETIDAE) en la dieta de Bothrops asper (SQUAMATA: VIPERIDAE) en las estribaciones noroccidentales de los Andes, Chitoa, Santo Domingo de los Tsáchilas, Ecuador.

open access: yesACI Avances en Ciencias e Ingenierías, 2019
Se reporta por primera vez la presencia de Melanomys caliginosus Ratón arrocero moreno (Rodentia: Cricetidae) en la dieta de la serpiente Bothrops asper para el Ecuador.
Hernán Orellana-Vásquez, Leandro Díaz
doaj   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar   +2 more
wiley   +1 more source

Effects of Two Fractions of Swietenia macrophylla and Catechin on Muscle Damage Induced by BothropsVenom and PLA2

open access: yesToxins, 2019
Plant natural products can attenuate the myonecrosis caused by Bothrops snake venom and their phospholipases A2 (PLA2). In this study, we evaluated the effects of two fractions (F4 and F6) from Swietenia macrophylla and purified catechin on the muscle ...
Silvia Posada Arias   +5 more
doaj   +1 more source

Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops asper

open access: yesComparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1992
1. In order to investigate the distribution of myotoxin isoforms in the snake Bothrops asper, venoms from individual specimens were analyzed by a cathodic electrophoretic system for basic proteins under native conditions. 2. The electrophoretic system resolved at least five bands with slight differences in mobility, corresponding to the fastest ...
Carmona Morera, Elena, Lomonte, Bruno
openaire   +4 more sources

Unraveling Biogeographic Boundaries Within the Sierra Madre Oriental, México: An Endemicity Analysis Using a Taxonomically Diverse Dataset

open access: yesEcology and Evolution, Volume 15, Issue 1, January 2025.
We provide boundaries of the Sierra Madre Oriental in Mexico through a multi‐taxa endemicity analysis. ABSTRACT The Sierra Madre Oriental (SMO) is a significant mountain range and one of Mexico's 14 biogeographical provinces. Its delimitation has been debated.
Irene Goyenechea Mayer‐Goyenechea   +5 more
wiley   +1 more source

Inhibición de las actividades proteolítica, coagulante y hemolítica indirecta inducidas por el veneno de Bothrops asper por extractos etanólicos de tres especies de heliconias [PDF]

open access: yes, 2008
En Colombia, Bothrops asper (mapaná) es la especie causante del 70 al 90% de los cerca de 3.000 accidentes ofídicos informados cada año. Durante varios siglos, la medicina tradicional ha utilizado plantas para el tratamiento de la mordedura de ...
Yessica RESTREPO   +7 more
core  

Pharmacological study of edema induced by venom of the snake Bothrops asper (terciopelo) in mice

open access: yes, 1995
The effect of several drugs on the edema-forming activity of Bothrops asper venom was studied plethysmographically using the mouse foot pad assay.
Gutiérrez, José María   +2 more
core   +1 more source

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