Results 51 to 60 of about 1,785 (202)
Unlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad [PDF]
, 2023 Funding Information: This work received financial support from PT national funds ( FCT/MCTES , Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the project CIRCNA/BRB/0281/2019 .
Aguiar, Luísa +13 more
core +1 more source
Toxins, 2013 A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass ...
Leonardo A. Calderon +9 more
doaj +1 more source
Jabuticaba (Plinia jaboticaba) skin extracts as inhibitors of phospholipases A2 and proteases
Anais da Academia Brasileira de Ciências: The phenolic extracts of jabuticaba skin flour (JSF) were characterized by HPLC, and evaluated for their modulating action upon phospholipases A2 and proteases of snake venom, aiming at their possible use in the treatment of the various diseases ...
TAMARA R. MARQUES +4 more
doaj +1 more source
Induction of mast cell accumulation, histamine release and skin edema by N49 phospholipase A [PDF]
, 2009 Background It has been recognized that phospholipase A2 (PLA2) is a crucial component of snake venom, which contributes greatly to snake venom induced inflammation in man. However, the mechanisms through which N49 PLA2 provoke inflammation remain unclear.
Ji-Fu Wei +3 more
core +2 more sources
Evidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017 Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects.
Juliana Félix-Silva +4 more
wiley +1 more source
Purification and biological effects of a C-type lectin isolated from Bothrops moojeni
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 Snake venom proteins from the C-type lectin family have very distinct biological activities despite their highly conserved primary structure, which is homologous to the carbohydrate recognition region of true C-type lectins.
PSF Barbosa +6 more
doaj +1 more source
Snake Venom PLA2, a Promising Target for Broad‐Spectrum Antivenom Drug Development
BioMed Research International, Volume 2017, Issue 1, 2017., 2017 Snakebite envenomation is a neglected global health problem, causing substantial mortality, disability, and psychological morbidity, especially in rural tropical and subtropical zones. Antivenin is currently the only specific medicine for envenomation. However, it is restricted by cold storage, snakebite diagnosis, and high price.
Huixiang Xiao +5 more
wiley +1 more source
BioMed Research International, Volume 2016, Issue 1, 2016., 2016 Snakebites are a serious worldwide public health problem. In Brazil, about 90% of accidents are attributed to snakes from the Bothrops genus. The specific treatment consists of antivenom serum therapy, which has some limitations such as inability to neutralize local effects, difficult access in some regions, risk of immunological reactions, and high ...
Jacyra Antunes dos Santos Gomes +9 more
wiley +1 more source
Clotting and fibrinogenolysis inhibition by essential oils from species of the Asteraceae family
Brazilian Archives of Biology and TechnologyEssential oils are pharmacologically active and unexplored compounds. The inhibitory properties of essential oils from Baccharis dracunculifolia, Conyza bonariensis, Tithonia diversifolia and Ambrosia polystachya were evaluated in the coagulation and ...
Cíntia Alvarenga Santos Fraga de Miranda +3 more
doaj +1 more source
Evidence-Based Complementary and Alternative Medicine, Volume 2015, Issue 1, 2015., 2015 We confirmed the ability of the triterpenoid betulin to protect against neurotoxicity caused by Bothrops jararacussu snake venom in vitro in mouse isolated phrenic nerve‐diaphragm (PND) preparations and examined its capability of in vivo protection using the rat external popliteal/sciatic nerve‐tibialis anterior (EPSTA) preparation.
Miriéle Cristina Ferraz +13 more
wiley +1 more source