Results 71 to 80 of about 1,785 (202)

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

Pharmacological and partial biochemical characterization of Bmaj-9 isolated from Bothrops marajoensis snake venom [PDF]

, 2020
Bmaj-9, a basic PLA2 (13679.33 Da), was isolated from Bothrops marajoensis snake venom through only one chromatographic step in reversed phase HPLC on ¼-Bondapak C-18 column.
Cruz-Höfling, M. A., Galbiatti, C., Marangoni, S., Ponce-Soto, L. A., Randazzo-Moura, P., Rocha, T., Rodrigues-Simioni, L.   +6 more
core   +1 more source

Interactions of small molecule inhibitors with secreted phospholipase A2: A review of the structural data

Chemical Biology &Drug Design, Volume 103, Issue 2, February 2024.
Due to their roles in inflammation, the sPLA2 enzymes are of much medicinal interest. sPLA2 inhibitors have been developed for the treatment of inflammatory and other conditions such as cardiovascular disease, arteriosclerosis and rheumatoid arthritis.
Chantalle Crous, Anél Petzer, Jacobus P. Petzer   +2 more
wiley   +1 more source

Haemotixic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise [PDF]

, 2017
Snake venoms are mixtures of numerous proteinacious components that exert diverse functional activities on a variety of physiological targets. Because the toxic constituents found in venom vary from species to species, snakebite victims can present with ...
Abubakar, Alirol, Alirol, Amiconi, Andrião-Escarso, Antonypillai, Arlinghaus, Arnold, Berling, Calvete, Calvete, Camargo, Casewell, Casewell, Casewell, Casewell, Casewell, Chakrabarty, Chippaux, Chippaux, Chippaux, Cousin, Deshpande, Durban, Earl, Escalante, Ferreira, Flight, Flight, Fox, Fry, Fry, Funk, Greene, Gutiérrez, Gutiérrez, Habib, Han, Harrison, Harrison, Harrison, Hutton, Illig, Isbister, Isbister, Isbister, Kasturiratne, Katkar, Kerkkamp, King, Kini, Lu, Lynch, Maduwage, Markland, Marrakchi, Marsh, Massey, McCleary, Modesto, Moll, Mosquera, Moura-da-Silva, Nowak, Oyama, Peerlinck, Phillips, Pirkle, Pla, Reza, Reza, Rivel, Rosing, Rucavado, Scarborough, Segura, Shimokawa, Siigur, Silva, Smith, Stocker, Stocker, Tan, Tan, Tan, Teixeira, Triplett, Vidal, Visser, Vonk, Vonk, Warrell, Warrell, Williams, Williams, Xu, Xu, Zhang   +97 more
core   +4 more sources

Protistas "incerta sedis" de ofídios do Brasil: Toddia França, 1912 e Pirhemocyton Chatton & Blanc, 1914: estudo comparativo "Incerta sedis" Portists from Brazilian snakes: Toddia França, 1912 and Pirhemocyton Chatton & Blanc, 1914: comparative study

Memorias do Instituto Oswaldo Cruz, 1973
Dentre 683 serpentes procedentes de diferentes pontos do Brasil, 16 (2,4%) apresentaram em seu sangue (em glóbulos vermelhos maturos e imaturos) Toddia ou Pirhemocyton.
Maria Auxiliadora de Sousa, Pérsio De Biasi, Samuel B. Pessoa   +2 more
doaj   +1 more source