The complement system in Botryllus schlosseri [PDF]
Among the various effector mechanisms involved in immune responses, the complement system is one of the most ancient, deeply-rooted and important for its ability to orchestrate different cells and factors of both innate and adaptive immunity. The comprehension of the evolution of the main complement components can provide clues to understand changes ...
FRANCHI NICOLA +2 more
core +4 more sources
Speed vs completeness: a comparative study of solitary and colonial tunicate embryogenesis [PDF]
Solitary ascidians, such as Ciona robusta, have been used for over a century as model systems for embryological studies. These species are oviparous, producing many relatively small and transparent eggs, which are released and fertilized outside the ...
Chiara Anselmi +7 more
doaj +2 more sources
Proteome-Wide 4-Hydroxy-2-Nonenal Signature of Oxidative Stress in the Marine Invasive Tunicate Botryllus schlosseri. [PDF]
ABSTRACT The ascidian Boytryllus schlosseri is a marine chordate that thrives under conditions of anthropogenic climate change. The B. schlosseri expressed proteome contains unusually high levels of proteins adducted with 4‐hydroxy‐2‐nonenal (HNE). HNE represents a prominent posttranslational modification resulting from oxidative stress.
Kültz D +6 more
europepmc +2 more sources
Aging in the colonial chordate, Botryllus schlosseri. [PDF]
What mechanisms underlie aging? One theory, the wear-and-tear model, attributes aging to progressive deterioration in the molecular and cellular machinery which eventually lead to death through the disruption of physiological homeostasis. The second suggests that life span is genetically programmed, and aging may be derived from intrinsic processes ...
Munday R +7 more
europepmc +4 more sources
Histocompatibility in Botryllus schlosseri and the origins of adaptive immunity. [PDF]
Abstract The basal chordate, Botryllus schlosseri , undergoes a natural transplantation reaction that is controlled by a single, highly polymorphic locus called the fuhc .
De Tomaso AW, Rodriguez-Valbuena H.
europepmc +3 more sources
Mechanical resilience of the sessile tunicate Botryllus schlosseri.
ABSTRACT We demonstrate that the sessile tunicate Botryllus schlosseri is remarkably resilient to applied loads by attaching the animals to an extensile substrate subjected to quasistatic equiradial loads. Animals can withstand radial extension of the substrate to strain values as high as 20% before they spontaneously detach.
Kwon Y +6 more
europepmc +3 more sources
Extensive Fouling of Eelgrass (<i>Zostera marina</i> L.) Reproductive Shoots by Invasive Tunicates-A Potential Threat to Meadow Reproductive Output? [PDF]
Here, we document through field observations and photographs, the extensive fouling of seed‐bearing Z. marina reproductive shoots by invasive tunicates in a Cape Cod meadow during late spring/early summer 2025. Such fouling may block seed release and/or inhibit dispersal which may reduce meadow reproductive success.
Scavo Lord K, Bennett-Smith M, Novak AB.
europepmc +2 more sources
Urochordate histoincompatible interactions activate vertebrate-like coagulation system components. [PDF]
The colonial ascidian Botryllus schlosseri expresses a unique allorecognition system. When two histoincompatible Botryllus colonies come into direct contact, they develop an inflammatory-like rejection response.
Matan Oren +4 more
doaj +1 more source
Transcriptome dynamics in the asexual cycle of the chordate Botryllus schlosseri. [PDF]
We performed an analysis of the transcriptome during the blastogenesis of the chordate Botryllus schlosseri, focusing in particular on genes involved in cell death by apoptosis. The tunicate B. schlosseri is an ascidian forming colonies characterized by the coexistence of three blastogenetic generations: filter-feeding adults, buds on adults, and ...
Campagna D +7 more
europepmc +5 more sources
Whole-mount fluorescent in situ hybridization staining of the colonial tunicate Botryllus schlosseri. [PDF]
Botryllus schlosseri is a colonial ascidian with characteristics that make it an attractive model for studying immunology, stem cell biology, evolutionary biology, and regeneration.
Langenbacher AD +3 more
europepmc +2 more sources

